Drugs of the Day 1 Flashcards
Acetylcysteine
B: Mucomyst
C: Mucolytic and Antidote
SE: Nephrotoxicity,
U: Tylenol Overdose, Atelectasis(lung collaps)
Acyclovir
B: Zovirax
C: Antiviral
U: Herpes Zoster, Varicellar Zoster
SE: Acute Kidney Injury
Adenosine
B: Adenocard
C: Class V antiarrhythmic
SE: Arrhythmias
U: PSVT,
Alteplase
B: Activase
C: Thrombolytic Agent
U: disintegrate blood clots,
restore central venous catheter function (IV Line)
SE: MI, Stroke, Pulmonary embolism
Amikacin
B: Amikin
C: Aminoglycoside Antibiotic
U: SERIOUS multi-drug resistant Gram
negative infections(Pseudomonas)
SE: Nephrotoxicity, Ototoxicity, Narrow therapeutic window, Draw peak and trough levels
Amiodarone
B: Cordarone
C: Class 3 antiarrhythmic
U: arrhythmia, atrial fibrillation
SE: Hypo/Hyperthyroidism, Pulmonary toxicity, increased
liver function tests
DI: Many!!!!! Including warfarin which could increase
the risk of bleeding.
Amphotericin B
B: Fungizone
C: Antifungal
U: Fungal Infections, Immunocompromised patients
SE: Nephrotoxicity, Infusion-related reactions if not premedicated with Ibuprofen,
hypokalemia(arrhythmias) , anemia
Ampicillin
B: N/A
C: Penicillin Antibiotic
U: Bacterial infections
SE: Hypersensitivity Reaction (cross-sensitivity with
cephalosporins and carbapenems.)
Cidal and DOC
Ampicillin / Sulbactam (B-Lactamase inhibitor)
B: Unasyn
C: Penicillin Antibiotic
U: Bacterial Infections, skin/soft tissue infections (Celulitis)
SE: Hypersensitivity Reaction (cross-sensitivity with
cephalosporins and carbapenems.)
Atropine
B: N/A
C: Anticholinergic / Antispasmodic
U: used before operation to decrease salivation and
secretions, also used to treat bradycardia
SE: Anticholinergic SE
Azithromycin
B: Zithromax
C: Macrolide Antibiotic
U: Community acquired pneumonia/upper respiratory tract infections, MAC in AIDS patient, immunocompromised patient
static
SE: QT prolongation
Aztreonam
B: Azactam
C: Monobactam Antibiotic
Cidal, NO cross sensitivity w/ other B-lactam
U: Gram-negative infections only (Pseudomonas)
Bumetanide
B: Bumex
C: Loop Diuretic
U: Edema associated with heart failure, renal, and/or liver disease
SE: Dehydration, Hypokalemia, Hyponatremia
Buprenorphine
B: Buprenex
C: Mixed opiate agonist/ antagonist
U: Heroin Withdrawal, Moderate to severe pain,
SE: Constipation, circulatory and respiratory depression
Caspofungin IV only
B: Cancidas
C: Antifungal
U: nvasive fungal infections (i.e. candida,
Aspergillus).
SE: Anemia, Immunocompromised patients
Cefazolin
B: Ancef
C: 1st generation Cephalosporin antibiotic
U: Skin and soft tissue infection (not MRSA), Surgical prophylaxis
SE: Hypersensitivity, Cross Sensitivity
Cidal
Cefepime
B: Maxipime
C: 4th generation Cephalosporin antibiotic
U: Hospital infection by Pseudomonas & Gram -ve rods, Immunosuppressed patient, fever
Cefotaxime
B: Claforan
C: 3rd generation Cephalosporin antibiotic
U: Lower respiratory tract infections, Some pediatric infections
NO Pseudomonas
Ceftazidime
B: Tazicef
C: 3rd generation Cephalosporin antibiotic
U: Nosocomial infections caused by Pseudomonas and other multidrug
resistant Gram negative rods
Ceftriaxone
B: Rocephin
C: 3rd generation Cephalosporin antibiotic
U:Community acquired pneumonia (in conjunction with a Macrolide)
IM for Gonorrhea
NOT Pseudomonas, & Neonates
SE: Biliary Sludging
Chlorpromazine
B: Thorazine
C: Typical Antipsychotic
U: Psychosis, Nausea/vomiting, DOC for intractable hiccups
SE: QT prolongation,
mask Parkinson’s, Extrapyramidal Effects (EPS), Tardive Dyskinesias, Sedating effects
Ciprofloxacin
B: Cipro
C: Fluoroquinolone Antibiotic
U: UTI, Hospital pneumonia W/ combination therapy.
SE: QT Prolongation, tendon rupture,
Not for HTN, PVD, history of aneurysm, not for <18YO, not for pregnant women.
Cidal
Cisplatin
B: Platinol
C: Antineoplastic
U: Bladder, testicular, and ovarian cancers.
SE: Ototoxicity, Nephrotoxicity, Neurotoxicity(seizures), GI toxicity
Clindamycin
B: Cleocin
C: Lincosamide Antibiotic
U:
Anaerobic Infections (some MRSA Strain), Prophylaxis for dental procedures
SE: N/V/D, Clostridium difficile
Static
Daptomycin
B: Cubicin
C: Lipopeptide Antibiotic
U: Skin and soft tissue infections caused by MRSA or other susceptible
Gram + bacteria
SE: Rhabdomyolysis,
Cidal
Darbepoetin Alfa
B: Aranesp
C: Colony Stimulating Factor
U: Anemia associated with chronic renal failure or chemotherapy
SE: Hypertension, infection
BBW: Increase due to clots, MI, Stroke, VTE
Dexamethasone
B: Decadron
C: Glucocorticosteroid
U: Pulmonary diseases, Septic shock, Cerebral edema, Preterm labor (to help with fetal lung maturation)
SE: Cushings syndrome, psychosis, osteoporosis
Lab Values: increase WBC, Glucose
Taper down if more than 7 days
Diazepam
B: Valium
C: LA Benzodiazepine
U: Status epilepticus, Anxiety, Adjunct to anesthesia
SE: Sedation, hypotension, bradycardia, and respiratory
depression, decrease HR, BP, RR
Digoxin
B: Lanoxin
C: Miscellaneous Antiarrhythmic
U: Heart failure, Atrial fibrillation
SE: Bradycardia
Drug TOX: GI, CNS(yellow halos), and arrhythmias
Must have levels
Diltiazem
B: Cardizem
C: Non-dihydropyridine Calcium Channel Blocker
U: Atrial fibrillation, Angina
SE: Bradycardia, hypotension
Diphenhydramine
B: Benadryl
C: H1 Histamine antagonist
U: Anaphylactoid reactions, Insomnia
U: Anticholinergic
Dobutamine
B: Dobutrex
C: Positive Inotrope
U: Cardiogenic shock
SE: Tachycardia, angina, increased
blood pressure
Not first line agent, mostly ICU
Dolasetron
B: Anzemet
C: Serotonin Receptor Antagonist
U: Prevention and treatment of nausea and
vomiting
SE: QT prolongation, increased serotonin syndrome,
Dopamine
B: Intropin
C: Vasopressor
U: Cardiogenic shock
SE: Tachycardia, angina
ICU only
Doripenem
B: Doribax
C: Carbapenem Antibiotic
U: Broad spectrum antibiotic used for multi-drug
resistant organisms including Pseudomonas
Warnings: Watch cross sensitivity with
penicillins/cephalosporins.
Cidal
QT Prolongation
Azithromycin, Ciprofloxacin, Dolasetron, Chlorpromazine
Cidal
Ampicillin, Aztreonam, Cefazolin, Ciprofloxacin, Daptomycin, Doripenem
Atrial fibrillation
Amiodarone, Digoxin, Diltiazem,
Nephrotoxicity
Amphotericin B, Acetylcysteine,
