drugs of misuse

Question 1

misuse of durgs act divides into what 3 categories?

Answer 1

A B C

Question 2

class A drug examples

Answer 2

cocaine
heroin
LSD

Question 3

class B examples

Answer 3

amfetamine
cannabis
ketamine
GHB

Question 4

class C examples

Answer 4

cathinone
testosterone

Question 5

stimulants: sympathomimetics physical signs of misuse?

Answer 5

dilated pupils
HTN
hyperreflexia
tachycardia
fine tremor
hypertonia
sweating

Question 6

serious med complications that cna occur with stimulants eg ecstasy?

Answer 6

convulsions
rhabdomyolysis
subarachnoid haemorrhage

Question 7

peripheral effects of cannabis?

Answer 7

tachycardia
vasodilation
reduction in intra ocular rpressure

Question 8

chronic cannabis use has been associated w increased risk of devleoping what?

Answer 8

schizophrenia

Question 9

opioid receptors mediate main pharmacological effects of opioids including….

Answer 9

analgesia
euphoria
pupil constriction
reduced GI motility
resp depression
sedation

Question 10

methadone given to treat opioid dependence as a heroin sub. it s a…

Answer 10

synthetic agonist w less sedative effects that morphine

Question 11

buprenorphine is a partial agonist so its maximal effect is more/less than morphine?

Answer 11

less

Question 12

naloxone = what type of drug?

Answer 12

opioid antagonist

Question 13

example of hallucinogen?

Answer 13

LSD- paper tabs
ketamine

Question 14

whats GHB (gamma hydroxybutyrate)?

Answer 14

an endogenous short chain fatty acid and struc analogue of the NT GABA

Question 15

acute tox of N2O (nitrous oxide) is caused by asphyxia, symptoms…?

Answer 15

headache
dizziness
confusion
syncope
seizures
cardiac arrythmias

Question 16

drugs used to suppress appetite (anoretics)

Answer 16

struc similar to amfetamine
laxative abuse
DNP
bumetanide (potent loop diuretic)
levothyrox
sibutramine
rimonabant

Question 17

OTC cough and cold remedies that may be abused?

Answer 17

codeine, dextromethorphan, pholcodine
diphenhydramine: sedating antihistamine
pseudoephedrine and ephedrine

Question 18

acute withdrawal alcohol: signs

Answer 18

tremor
sweating
tachycardia
dleirium

signs of wernickes encephalopathy
chronic liver disease
hepatic enceph

Question 19

3 drugs that may be used in long term management of alcohol dependence?

Answer 19

acamprosate
naltrexone
disulfiram

Question 20

acamprosate acts as what?

Answer 20

a functional glutamatergic NMDA antagonist

Question 21

what is naltrexone?

Answer 21

long acting opioid antagonist that reduces alcohols rewarding effects and craving

Question 22

what does disulfiram block?

Answer 22

aldehyde dehydrogenase activity –> acetylaldehyde is alcohol is consumed.

–> nausea and vomiting, flushing, palpitations

Question 23

most used meds for assissted withdrawal of alcohol?

Answer 23

chlordiazepoxide
diazepam
oxazepam

Question 24

signs and symptoms of benzodiazepine withdrawal?

Answer 24

agitation
ocnfusion
convulsions
hyperreflexia
irritability insomnia

Question 25

opioid withdrawal signs?

Answer 25

GI
CNS
others…yawning, goosebumps

Question 26

methadone can cause…2

Answer 26

resp depression and arrhythmias