dementia friendly prescribing Flashcards

1
Q

some meds can increase risk of delirium

examples of 2 drug classes that can precipitate acute confusion, or acute on chronic confusion?

A

benzos (diazepam)
anticholinergic agents (oxybutinin)

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2
Q

the 3 key mental functions impaired in dementia?

A

cognition: memory, speech, apraxia

neuropsychiatric: character and behavioural change

activities of daily living

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3
Q

diagnosing dementia in hospital, what does FAIR stand for?

A

Find ppl w dementia, and Family/Friends if any signs of memory loss

Assess for risk

Investigate

Refer

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4
Q

the ICD10 criteria for dleirium

A

impaired consc/attention
global cognitive impairment
psychomotor changes
disturbed sleep/wake cycle
emotional disturbance

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5
Q

how is delirium different/distinguishable from dementia?

A

its acute confusional state.
rapid onset fluctuating course and transcience

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6
Q

risk factors for delirium?

A

acute illness
old age
pre-existing dmenetia
sensory impairment

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7
Q

delirium preciptatnts? 5

A

meds: anticholinergics, benzos, anti-parkinsonnism agents

infection: resp/urinary tract

metabolism problems

substance musure

direct brain insult

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8
Q

somatic (biological) symptoms of mood disorders?

A

diurnal variation of mood
diff appetite
reduced conc
agitation
hypersomnia/ waking early
weight loss/gain

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9
Q

most common type of dementia?

A

alzheimers

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10
Q

prognosis of alcheimers is….

A

between 5-10yrs from diagnosis to death

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11
Q

whats vascular dementia?

A

VaD= dementia caused by cerebrovasc diseases

hard to distinguish form alzheimers

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12
Q

features that most rleiably distinguish VaD?

A

abrupt onset
HTN
history of stroke
CT/ MRI evidence

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13
Q

which med should be considered for therapeutic improvement of PDD? parkisons disease dementia?

A

donepazil, galantamine, rivastigmine = all acetylcholinesterase inhibitors but only RIVASTIGMINE = clinical efficacy in px w mild-mod PDD

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14
Q

name the 3 acetylcholinesterase inhibitors

A

donepazil
galantamine
rivastigmine

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15
Q

name the partial antagonist of NMDA receptors

A

memantine

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16
Q

licensed drugs for mild-mod alzheimers?

A

donepazil
galantamine
rivastigmine

17
Q

licensed drug for mod- severe alzheimers?

A

memantine

18
Q

licensed drug for mild-mod PDD?

A

rivastigmine

19
Q

meds affecting cognition?

A

antimuscarinics: oxybutinin, procyclidine, antideps

hypnotics and anxiolytics: sedatives(benzos)