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Microbiology Misc > Drugs of Choice > Flashcards

Drugs of Choice Flashcards

1
Q

Staphylococcus aureus

A

Penicillinase-resistant penicillins (nafcillin, oxacillin, dicloxacillin)

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2
Q

MRSA

A

Vancomycin

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3
Q

VRSA

A

Linezolid

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4
Q

Staphylococcus epidermidis

A

Vancomycin

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5
Q

Staphylococcus saprophyticus

A

TMP-SMX, quinolones

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6
Q

Streptococcus pyogenes

A

Penicillin G

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7
Q

Streptococcus agalactiae

A

Penicillin G

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8
Q

Streptococcus pneumoniae

A

Penicillin G

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9
Q

viridans Streptococci

A

Penicillin G ± aminoglycoside

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10
Q

Enterococci

A

Penicillin
Vancomycin for penicillin resistance
Linezolid for vancomycin resistance

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11
Q

Bacillus anthracis: cutaneous

A

Ciprofloxacin

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12
Q

Bacillus anthracis: inhalational

A

Ciprofloxacin OR doxycycline + 1-2 additional abx

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13
Q

Bacillus cereus: food poisoning

A

Symptomatic treatment only

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14
Q

Clostridium tetani

A

Penicillin (microbio-wise)

Metronidazole (HPIM)

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15
Q

Clostridium botulinum

A

Supportive tx + antitoxin

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16
Q

Clostridium perfringens

A

Penicillin G

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17
Q

Clostridium difficile

A

Metronidazole PO or Vancomycin PO

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18
Q

Corynebacterium diphtheriae

A

Penicillin G + antitoxin

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19
Q

Listeria monocytogenes

A

Ampicillin ± Gentamicin

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20
Q

Neisseria meningitidis

A

Penicillin G

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21
Q

Neisseria meningitidis prophylaxis

A

Rifampin OR Ciprofloxacin OR Ceftriaxone IM

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22
Q

Neisseria gonorrhoeae

A

Ceftriaxone + Doxycycline (due to frequent Chlamydia co-infection)
Spectinomycin for resistance

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23
Q

Haemophilus influenzae

A

Ceftriaxone

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24
Q

Bordetella pertussis

A

Erythromycin

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25
Q

Legionella pneumophila

A

Azithromycin OR Erythromycin

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26
Q

Escherichia coli

A

Ampicillin OR TMP-SMX

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27
Q

Escherichia coli: UTI

A

Quinolones

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28
Q

Escherichia coli: Meningitis, sepsis

A

3rd-gen cephalosporins

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29
Q

Salmonella typhi: Uncomplicated typhoid fever

A

Amoxicillin OR Chloramphenicol

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30
Q

Salmonella typhi: Severe typhoid fever

A

Ampicillin OR Ceftriaxone

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31
Q

Shigella spp.

A

Ciprofloxacin

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32
Q

Vibrio cholerae

A

Tetracycline OR Azithromycin

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33
Q

Campylobacter jejuni

A

Erythromycin (severe cases)

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34
Q

Helicobacter pylori

A

Triple therapy (OAC or OMC) OR Quad therapy (OBMT)

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35
Q

Klebsiella pneumoniae

A

3rd gen cephalosporin + aminoglycoside (empiric)

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36
Q

Proteus mirabilis

A

TMP-SMX OR Ampicillin

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37
Q

Bacteroides fragilis

A

Metronidazole, Clindamycin OR Cefoxitin

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38
Q

Brucella abortus

A

Doxycycline + Rifampin

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39
Q

Francisella tularensis

A

Streptomycin OR Gentamicin

40
Q

Yersinia pestis

A

Streptomycin + Tetracycline

41
Q

Pasteurella multocida

A

Penicillin G

42
Q

Mycobacterium avium intracellulare

A

Azithromycin

43
Q

Mycobacterium leprae

A

Rifampin, Dapsone, Clofazimine

44
Q

Actinomyces israelii

A

Penicillin G

45
Q

Nocardia asteroides

A

TMP-SMX

46
Q

Mycoplasma pneumoniae

A

Erythromycin OR Azithromycin

47
Q

Treponema pallidum

A

Penicillin G

48
Q

Borrelia burgdorferi

A

Doxycycline

49
Q

Borrelia recurrentis

A

Tetracycline OR Erythromycin

50
Q

Leptospira interrogans: Mild infection

A

Doxycycline OR Ampicillin/Amoxicillin

51
Q

Leptospira interrogans: Severe infection

A

Penicillin G, Ampicillin, Cefotaxime, Ceftriaxone

52
Q

Leptospira interrogans: Prophylaxis

A

Doxycycline

53
Q

Chlamydia: STD

A

Azithromycin

54
Q

Chlamydia: Conjunctivitis

A

Erythromycin

55
Q

Chlamydia: LGV

A

Doxycycline

56
Q

Chlamydia: Psittacosis

A

Azithromycin

57
Q

Rickettsiae

A

Doxycycline

58
Q

Klebsiella granulomatis

A

Azithromycin

59
Q

Sporothrix schenckii

A

Itraconazole OR Potassium iodide

60
Q

Coccidioides immitis

A

Itraconazole OR Amphotericin B

61
Q

Histoplasma capsulatum

A

Itraconazole OR Amphotericin B

62
Q

Blastomyces dermatitidis

A

Itraconazole OR Amphotericin B

63
Q

Paracoccidioides brasiliensis

A

Itraconazole OR Amphotericin B

64
Q

Cryptococcus neoformans

A

Flucytosine, Amphotericin B, Fluconazole

65
Q

Aspergillus fumigatus

A

Amphotericin B

66
Q

Pneumocystis jiroveci

A

TMP-SMX

67
Q

HSV

A

Acyclovir

68
Q

VZV

A

Acyclovir

69
Q

CMV

A

Ganciclovir

70
Q

Molluscum contagiosum virus

A

Cifodovir

71
Q

HBV

A

Lamivudin, IFN-ɑ

72
Q

HCV

A

Ribavirin

73
Q

Influenza virus

A

Oseltamivir OR Zanamivir

Inf A: Amantadine, Rimantadine

74
Q

HIV

A

HAART: Ziduvudine, Lamivudine, Indinavir

75
Q

Entamoeba histolytica: Cyst carrier state

A

Diloxanide furoate

76
Q

Entamoeba histolytica: Amebic colitis, amebic liver abscess

A

Metronidazole

77
Q

Giardia lamblia

A

Metronidazole

78
Q

Cryptosporidium parvum

A

Nitazoxanide

79
Q

Trichomonas vaginalis

A

Metronidazole

80
Q

Plasmodium spp: Standard therapy

A

Chloroquine

81
Q

Plasmodium spp: Hypnozoites

A

Primaquine

82
Q

Toxoplasma gondii

A

Sulfadiazine + Pyrimethamine

83
Q

Trypanosoma cruzi

A

Nifurtimox

84
Q

Trypanosoma brucei gambiense

A

Pentamidine + Eflornithine

85
Q

Trypanosoma brucei rhodiense

A

Suramin + Melarsoprol

86
Q

Leishmania spp.

A

Sodium stibogluconate

87
Q

Echinococcus granulosus

A

Albendazole

88
Q

Schistosoma, Paragonimus
Clonorchis sinensis, Opistorchis viverrini
D. latum, T. saginata, T. solium

A

Praziquantel

89
Q

Ascaris lumbricoides

A

Albendazole

90
Q

Necator, Ancylostoma

A

Albendazole

91
Q

Trichiuris trichiura

A

Mebendazole

92
Q

Enterobius vermicularis

A

Pyrantel pamoate

93
Q

Strongyloides stercoralis

A

Ivermectin

94
Q

Capillaria philippinensis

A

Albendazole

95
Q

Wuchereria, Brugia

A

Diethylcarbazepine (DEC)

96
Q

Trichinella spiralis

A

Thiabendazole

Microbiology Misc (3 decks)

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