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AUTONOMY PHARMCOLOGY > DRUGS NAME > Flashcards

DRUGS NAME Flashcards

1
Q

LIST TYPICAL DRUGS OF SCHIZOPHENIA

A

HALOPERIDOL
ZUCLOPENTHIXOL
SULPIRIDE
PROCHLOROPERAZINE
CHLOROPROMAZINE

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2
Q

WHAT IS MOA OF PROCHLOROPERAZINE

A

-BLOCK DOPAMINE REUPTAKE
- EFFECTIVE TOWARDS POSITIVE SYMPTOMS

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3
Q

WHY ZUCLOPENTHIXOL DIDNT RECOMMEND AS A FIRST LINE TREATMENT IN SCHIZOPHENIA

A

GIVING EXTRAPRAMYDAL SIDE EFFECT

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4
Q

WHY QUETIAPINE WAS RECOMMENDED AS FIRST LINE TREATMENT IN SCHIZOPHENIA

A

ITS GIVING METABOLIC CHANGES SUCH AS HYPERGLYCEMIA , HYPERLIPIDEA AND EXCESSIVE WEIGHT GAIN

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5
Q

WHAT IS MOA OF OLAZAPINE

A

-BLOCK DOPAMINE AND SEROTONIN IN SOME EXTENT
- EFFECTIVE TOWARDS POSITIVE AND NEGATIVE SYMPTOMS IN SOME EXTENT

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6
Q

NAME DRUG THAT WAS GIVING AFTER 2 ANTIPSYCHOTICS DRUGS FAILED TO RESPOND IN PATIENT AND WHY

A
  • CLOZAPINE
  • AS A ;LAST RESORT OF TREATMENT
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7
Q

LIST ATYPICAL ANTIPSYCHOTICS DRUGS

A
  • OLAZAPINE
    -CLOZAPINE
  • AMISULPRIDE
  • ARIPIPRAZOLE
  • QUETIAPINE
    -RISPERIDONE
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8
Q

LIST NAME ANTI DEPRESSANT DRUGS IN TRYCLIC ANTI DEPRESSANT (TCA)

A
  • NORTRIPTYLINE
  • AMITRIPTYLINE
    -CLOMIPRAMINE
    -DOTHIEPIN HCL
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9
Q

WHAT IS MOA OF AMITRIPTYLINE

A

BLOCK SEROTONIN AND NORADRENALINE REUPTAKE TRANSPORTER

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10
Q

WHAT IS PHARMACOLOGICAL CLASS OF PHENELZINE

A

MONOAMINE OXIDASE INHIBITOR ANTI DEPRESSANT

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11
Q

EXPLAIN WHAT SHOULD PATIENT BE AWARE WHEN PRESCRIBED WITH PHENELZINE

A

-HIGH TYRAMINE FOOD
-SINCE THERE IS NOT MONOAMINE OXIDASE ENZYME MORE TYRAMINE AVAILABLE IN OUR BODY
- HENCE IT CAN LEAD TO HYPERTENSION

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12
Q

EXPLAIN MOA OF PHENELZINE

A
  • INHIBIT MONOAMINE OXIDASE ENZYME THAT DEGRADE SEROTONIN AND NORADRENALINE
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13
Q

WHAT IS PHARMACOLOGICAL CLASSIFICATION OF ESCITALOPRAM

A

SELECTIVE SEROTONIN REUPTAKE INHIBTOR ANTI DEPRESSANT

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14
Q

WHAT IS MOA OF CITALOPRAM

A

-SELECTIVELY INHIBIT SEROTONIN REUPTAKE
-HENCE MORE SEROTONIN AVAILABLE

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15
Q

WHY DID PATIENT CONDITION STILL NO PROGRESSION AFTER 1-2 WEEKS OF PRESCRIBED DRUG

A
  • WHEN TAKING ANTI DEPRESSANT DRUG IN EARLY TREATENT, IT ACTIVATED THE AUTO RECEPTOR OF SEROTONIN.
    -IT GIVING NEGATIVE FEEDBACK
  • HENCE MORE SEROTONIN AVAILABLE
  • HOWEVER AFTER 4- 6 WEEKS. AUTORECEPTOR WILL BE DECREASED
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16
Q

WHAT IS SEROTONIN SYNDROME

A
  • LIFE THREATENING CONDITION DUE OF EXCESSIVE LEVEL OF SEROTONIN
    -LEADS TO SYMPTOMS SUCH AS HIGH FEVER AND INDUCE SEIZURE
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17
Q

LIST SSRI DRUGS

A

-CITALOPRAM
-ESCITALOPRAM
-FLUOXETINE
-SETRALINE
-FLUROXAMINE
-PAROXETINE

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18
Q

WHAT IS PHARMACOLOGICAL CLASSIFICATION OF VENLAFAXINE

A

SEROTONIN NORADRENALINE REUPTAKE INHIBITOR

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19
Q

WHAT IS MOA OF DESVENLAFAXINE

A

BLOCK SEROTONIN AND NORADRENALINE REUPTAKE TRANSPORTER

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20
Q

LIST SNRI DRUGS

A

DULOXETINE
VENLAFAXINE
DESVENLAFAXINE

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21
Q

LIST ANTI EPILEPTIC DRUGS

A

PHENYTOIN
CARBAMAZEPINE
SODIUM VALPORATE
LAMOTRIGINE
LEVETIRACETAM

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22
Q

WHAT IS PHENYTOIN SIDE EFFECTS

A

HIRSUTISM
GINGIVAL HYPERPLASIA
CLEFT PALATE

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23
Q

WHAT IS CARBAMAZEPINE SIDE EFFECTS

A

DIPLOPIA
JAUNDICE
BRUISING

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24
Q

WHAT DRUGS IS TOXICITY TO PREGNANT WOMAN AND WHY

A

SODIUM VALPORATE
IT DISRUPT FOLATE METABOLISM LEAD TO NEURAL TUBE DEFECT

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25
Q

WHAT DRUGS IS SAFE FOR PREGNANCY AND ANY ADVICE TO PATIENT

A

CARBAMAZEPINE
LAMOTRIGINE

PATIENT SHOULD TAKE ACID FOLID SUPPLEMENT AND VITAMIN K INJECTION

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26
Q

WHAT IS PHARMACOLOGICAL CLASSIFICATION OF ALPRAZOLAM

A

BENZODIAPINE

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27
Q

WHAT IS MOA OF DIAZEPAM

A

ENHANCE GABA EFFECTS
HENCE REDUCE OVEREACT IN NERVOUS SYSTEM

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28
Q

WHAT IS POSSIBLE EFFECTS PATIENT WILL HAVE WHEN PRESCRIBES WITH LORAZEPAM

A

FALLS
SEDATION
DEPENDENCE

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29
Q

LIST BENZODIAPINES DRUGS

A

ALPRAZOLAM
LORAZEPAM
DIAZEPAM
MIDAZOLAM
CHLODIAZEPOXIDE

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29
Q

WHAT IS MIDAZOLAM INDICATION FOR

A

ANXIETY AND INSOMNIA

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30
Q

LIST DRUGS IN Z DRUGS PHARMACOLOGICAL CLASS

A

ZALEPION
ZOLPIDEM
ZOPICLONE

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31
Q

WHAT IS MOA OF ZALEPION

A

ENHANCE GABA EFFECTS BY BINDING TO ANOTHER SIDE OF RECEPTOR

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32
Q

WHAT INDICATION ARE WHEN PATIENT WAS PRESCRIBED WITH BUSPIRONE

A

ANXIETY

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33
Q

WHAT MOA OF BUSPIRONE

A

INCREASED SEROTONIN LEVEL

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34
Q

LIST GENERAL ANESTHETIC THAT WAS AVAILABLE AS IV DRIPS

A

PRPOFOL
THIOPENTAL SODIUM
ETOMIDATE
KETAMINE

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35
Q

WHAT IS GENERAL ANESTHETIC THAT AVAILABLE AS INHALED GAS

A

ISOFLURANE
SEROFLURANE
DESFLURANE
NITROUS OXIDE

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36
Q

LIST LOCAL ANESTHETIC

A

LIDOCAINE
NOVOCAINE
BENZOCAINE
TETRACAINE
BUPIVACAINE

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37
Q

WHAT IS PHARMACOLOGICAL CLASSIFICATION OF DONEPEZIL

A

ANTI CHOLINESTERASE IN ALZHEIMER’S

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38
Q

WHAT IS MOA OF GALANTAMINE

A

INHIBIT CHOLINESTERASE ENZYME
MORE ACETYLCHOLLINE AVAILABLE

39
Q

WHAT IS RIVASTAGMINE POSSIBLE SIDE EFFECTS

A

LOSS APETITE
NAUSEA
VOMITTING

40
Q

WHAT IS PHARMACOLOGICAL CLASSIFICATION OF MEMANTINE

A

NMDA RECEPTOR ANTAGONIST

41
Q

WHAT IS MOA OF MEMANTINE

A

INHIBIT NMDA RECEPTOR
DECREASED LECEL OF GLUTAMATE
HENCE REDUCE EXCITOTOXICITY AND NEURON DEATH

42
Q

WHAT IS MOA OF LEVODOPA

A

ENSURING DOPAMINE CAN PASS THORUGH BLOOD BRAIN BARRIER

43
Q

WHAT IS PHARMACOLOGICAL CLASS OF LEVODOPA

A

DOPAMINE PRECUSOR ANTI PARKINSON

44
Q

WHY DID LEVODOPA WAS USED AS LAST TREATMENT OF PARKINSON

A

IT GIVING DYSKINESIA,WEARING OFF AND ON-OFF SIDE EFFECTS

45
Q

WHAT DRUGS THAT WAS USED SYNERGERSTICALLY WITH LEVODOPA AND STATE THEIR PHARMACOLOGICAL CLASS

A

CARBIDOPA
BENSERAZIDE
-DECARBOXYLASE INHIBITOR

46
Q

WHAT IS MOA OF CARBIDOPA

A

REDUCE CONVERSION OF LEVODOPA INTO DOPAMINE
TO REDUCE LEVODOPA LONG TERM SIDE EFFECT

47
Q

WHAT DRUGS IS LISTED UNDER MAOB INHIBITOR IN ANTI PARKINSON

A

SELEGILINE
RASAGILINE

48
Q

WHAT IS MOA OF RASAGILINE

A

INHIBIT MAOB ENZYME THAT HELP IN DEGRADATION OF DOPAMINE
HENCE MORE DOPAMINE AVAILABLE INSIDE BRAIN

49
Q

WHAT IS ENTACAPONE MOA

A

INHIBIT COMT ENZYME THAT HELP IN DEGRADATION OF LEVODOPA
MORE LEVODOPA AVAILABLE OUTSIDE BRAIN

50
Q

WHAT IS PHARMACOLOGICAL CLASSIFICATION OF TOLCAPONE

A

COMT INHIBITOR ANTI PARKINSON

51
Q

WHAT IS AMANTADINE MOA

A

MIMICKING DOPAMINE EFFECTS IN OUR BRAIN

52
Q

WHAT IS PHARMACOLOGICAL CLASSIFICATION OF PIRIBEDIL

A

DOPAMINE AGONIST

53
Q

WHY IS PATIENT CANT CONTROL THEIR HABIT SUCH AS SHOPPING WHEN PRESCRIBED WITH PRAMIPEXOLE

A

GIVING SUDDEN IMPULSE CONTROL SIDE EFFECTS

54
Q

WHAT DRUG IN DOPAMINE AGONIST ANTI PARKINSON

A

BROMOCLIPTINE
AMANTADINE
PIRIBEDIL
PRAMIPEXOLE

55
Q

WHAT IS PROCYCLIDINE MOA

A

REDUCE ACETYLCHOLINE HENCE BALANCING DOPAMINE LEVEL

56
Q

WHAT IS PHARMACOLOGICAL CLASSIFICATION OF TRIHEXYLPHENIDYL

A

ANTI MUSCARINIC

57
Q

WHAT IS MOA OF METFORMIN

A

REDUCE GLUCOGENESIS
INCREASE INSULIN SENSITIVITY
REDUCE GLUCOSE ABSORPTION

58
Q

WHAT DRUGS IS IN SULPHONYLUREAS

A

GLICAZIDE
GLIMEPIRIDE

59
Q

WHAT IS MOA OF GLICAZIDE

A

INCREASE INSULIN PRODUCTION IN PANCREAS

60
Q

THE POSSIBLE SIDE EFFECTS OF GLIMEPIRIDE

A

HYPOGLYCEMIA AND WEIGHT GAIN

61
Q

WHAT IS MOA OF ACARBOSE

A

DELAY CARBOHYDRATES DIGESTION
SLOW DOWN GLUCOSE ABSORPTION

62
Q

WHAT IS ADVICE SHOULD BE GIVEN TO PATIENT WHEN TAKE ACARBOSE

A

USE SANITARY PAD ON MORNING
TAKE WITH MOUTHFUL OF LIQUID OR FOOD

63
Q

LIST DRUG UNDER DIPEPTIDYL-PEPTIDASE 4 INHIBITOR (DPP4i)

A

SITAGLIPTIN
VILDAGLIPTIN
LINAGLIPTIN

64
Q

VILDAGLIPTIN MOA

A

INHIBIT INCRETIN BREAKDOWN
HELPS IN INCREASING INSULIN SECRETION
SLOW DOWN GLUCOSE ABSORPTION

65
Q

LINAGLIPTIN SIDE EFFECTS

A

HYPOGLYCEMIA

66
Q

DRUGS UNDER GLUCAGON-LIKE PEPTIDE -1 RECEPTOR

A

LIRAGLUTIDE
DULAGLUTIDE
SEMAGLUTIDE
EXENATIDE
LIXISENATIDE

67
Q

LIXISENATIDE MOA

A

MIMICS INCRETIN FUNCTION
SLOW DOWN GLUCOSE ABSORPTION
INCREASE INSULIN SECRETION

68
Q

SEMAGLUTIDE SIDE EFFECTS

A

WEIGHT LOSS

69
Q

METFORMIN SIDE EFFECTS

A

WEIGHT LOSS
PERIPHERAL NEUROPAHTY

70
Q

WHAT IS PHARMACOLOGICAL CLASS OF EMPAGLIFLOZIN

A

SODIUM GLUCOSE 2 TRANSPORTER INHIBITOR

71
Q

WHAT CANAGLIFLOZIN MOA

A

SELECTIVE INHIBIT SODIUM GLUCOSE 2 TRANSPORTER IN KIDNEY
REDUCE GLUCOSE READSORPTION INTO BLOOD
INCREASE INSULIN EXCRETION IN URINE

72
Q

POSSIBLE EFFECT OF DAPAGLIFLOZIN

A

UTI
WEIGHT LOSS
DEHYDRATION

73
Q

BENEFIT OF CANAGLIFLOZIN

A

CARDIOPROTECTIVE
HEART FAILURE TREAMENT
RENOPROTECTIVE

74
Q

INSULIN MOA

A

FACILITATE GLUCOSE UPTAKE BY BODY CELL FROM BLOOD

75
Q

INSULIN SIDE EFFECT

A

HYPOGLYCEMIA
FAT ACCUMULATION
WEIGHT GAIN

76
Q

HYPOTHYROID DRUG

A

LEVOTHYROXINE
THYEOXINE SODIUM
LITHYROXINE SODIUM INJECTION

77
Q

LEVOTHYROXINE MOA

A

REPLACE NATURAL HORMON THYROID

78
Q

ADVICE WHEN TAKING LEVOTHYROXINE

A

ON MORNING ONCE DAILY
30 MINS BEFORE BREAKFAST OR CAFFIENE

79
Q

HYPERTHYROID DRUGS

A

CARBIMAZOLE
PROPYLTHIOURACIL

80
Q

PROPYLTHIOURACIL MOA

A

REDUCE THYROID HORMONE PRODUCATION

81
Q

WHY IS CARBIMAZOLE IS DANGER DRUG

A

CAUSE BIRTH DEFECT

82
Q

LIST COMBINED ORAL CONTRACEPTIVES

A

YASMIN
YAZ
QLAIRA
NORDETTE
MARVELON
MERECILON
COTTE
DIANE 35

83
Q

DIANE 35 MOA

A

PREVENT OVULATION
THICKEN CERVICAL MUCUS
PREVENT SPERM REACHS OVUM

84
Q

IS QLAIRA SAFE FOR PREGNANCY AND WHY

A

NO.
INCREASED BLOOD CLOT

85
Q

WHAT IS NORIDAY MOA

A

THICKEN CERVICAL MUCUS
THINNING UTERINE LINE

86
Q

IS CERAZETTE SAFE IN PREGNANCY

A

YES

87
Q

EXPLAIN EMERGENCY PILLS AND EXAMPLE

A

POSTINOR-2 AND ESCAPELLE WILL DELAYS OVULATION WITHIN 72 HOURS
ELLAONE BLOCK OVULATION WITHIN 120 HOURS

88
Q

LIST ACUTE MIGRAINE TREATMENT

A

SUMATRIPTAN
ALMOTRIPTAN
ZOLMITRIPTAN
RIZATRIPTAN
ERGOTAMINE CAFFIENE

89
Q

WHAT IS SUMATRIPTAN MOA

A

ACTIVATE SEROTONIN RECEPTOR HENCE LESS RELEASE NEUROPEPTIDE
LESS NOCICEPTOR ACTIVATION AND VASODILATION

90
Q

ZOMITRIPTAN SIDE EFFECTS

A

HOT FLUSHING
SENSATION
DROWSY

91
Q

EXPLAIN HOW SHOULD WE TAKE MIGRAINE TREATMENT

A

WHEN MIGRAINE SYPMTOPS OCCUR TAKING NSAID OR PAIN KILLER ASAP
WHEN MIGRRAINE START TO ATTACK TAKE TRIPTAN DRUGS

92
Q

WHAT IS MOA OF CORTICOSTEROID

A

REDUCE INFLAMMATION AND MODULATE IMMUNE SYSTEM

93
Q

WHAT IS BETHAMETHAOSONE SIDE EFFECTS IF USE LONG TERM

A

OSTEOPOROSIS
CUSHING SYNDROME
BETHAMETHASONE HIGH POTENCY TOPICAL CREAM.

94
Q

STEROID FUNCTION

A

ENHANCE RECOVERY AND REDUCE FATIGUE
MIMICS MALE SEX HORMONE AND PROMOTE TISSUE AND MUSCLE GROWTH.

95
Q

EXAMPLE OF STEROID

A

TESTERONE
NANDRONOLE
STANOZOL
METHENOLONE

96
Q

CORTICOSTEROID EXAMPLE

A

HYDROCORTISONE
PREDNISOLONE
DEXAMETHASONE
BUDESONIDE

AUTONOMY PHARMCOLOGY (2 decks)

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