Drugs In Sympathetic Nervous System Flashcards
What is the primary neurotransmitter of the sympathetic nervous system?
The primary neurotransmitter of the sympathetic nervous system is norepinephrine (noradrenaline).
What are the two main types of adrenergic receptors?
The two main types of adrenergic receptors are alpha-adrenergic receptors and beta-adrenergic receptors.
Which class of drugs acts by blocking the alpha-adrenergic receptors?
The class of drugs that acts by blocking the alpha-adrenergic receptors is known as alpha blockers (alpha-adrenergic antagonists)
Which class of drugs acts by stimulating the beta-adrenergic receptors?
The class of drugs that acts by stimulating the beta-adrenergic receptors is known as beta agonists (beta-adrenergic agonists).
What is the primary therapeutic use of alpha blockers?
Alpha blockers are primarily used for the management of hypertension (high blood pressure) and benign prostatic hyperplasia (enlarged prostate).
What are the common side effects of alpha blockers?
Common side effects of alpha blockers include orthostatic hypotension (low blood pressure upon standing), dizziness, and fatigue.
Give an example of a non-selective beta blocker.
Propranolol is an example of a non-selective beta blocker that blocks both beta-1 and beta-2 adrenergic receptors.
What is the main therapeutic use of beta blockers?
Beta blockers are commonly used for the management of hypertension, angina (chest pain), arrhythmias, and heart failure.
Which beta blocker is preferred in patients with asthma or chronic obstructive pulmonary disease (COPD)?
Selective beta-1 blockers, such as metoprolol and atenolol, are preferred in patients with asthma or COPD due to their lesser effect on beta-2 receptors in the lungs.
What is the mechanism of action of beta-2 agonists?
Beta-2 agonists stimulate the beta-2 adrenergic receptors, leading to bronchodilation and relaxation of the smooth muscles in the airways.