Drugs In Parasympathetic Nervous System Flashcards
What is the primary neurotransmitter of the parasympathetic nervous system?
The primary neurotransmitter of the parasympathetic nervous system is acetylcholine.
What is the main therapeutic use of muscarinic agonists?
Muscarinic agonists are primarily used to stimulate smooth muscle contraction in the gastrointestinal tract and bladder, and to lower intraocular pressure in conditions like glaucoma.
Give an example of a muscarinic agonist.
Bethanechol is an example of a muscarinic agonist used to treat urinary retention and postoperative ileus.
What is the primary therapeutic use of muscarinic antagonists?
Muscarinic antagonists are commonly used to treat conditions involving excessive parasympathetic activity, such as overactive bladder, motion sickness, and certain gastrointestinal disorders.
Give an example of a muscarinic antagonist.
Scopolamine is an example of a muscarinic antagonist used to prevent motion sickness and nausea.
What is the mechanism of action of cholinesterase inhibitors?
Cholinesterase inhibitors inhibit the breakdown of acetylcholine, leading to increased cholinergic activity in the parasympathetic nervous system.
What is the main therapeutic use of cholinesterase inhibitors?
Cholinesterase inhibitors are commonly used in the treatment of Alzheimer’s disease to improve cognition and memory.
Give an example of a reversible cholinesterase inhibitor.
Donepezil is an example of a reversible cholinesterase inhibitor used in Alzheimer’s disease.
What is the main therapeutic use of anticholinergic agents?
Anticholinergic agents are used to treat various conditions, including overactive bladder, chronic obstructive pulmonary disease (COPD), and parkinsonism.
Give an example of an anticholinergic agent.
Tiotropium is an example of an anticholinergic agent used as a long-acting bronchodilator in COPD.
