Drugs in kidney disease Flashcards
1
Q
Which drugs are excreted by kidneys and so accumulate in the body in renal failure?
A
Digoxin Lithium Morphine Pethidine Penicillin, gentamicin, vancomycin, erythromycin, aciclovir
2
Q
Which drug require HIGHER doses in renal failure?
A
Furosemide
uraemia makes kidneys less sensitive to furosemide so higher doses are needed
3
Q
Spironolactone cause …
A
Hyperkalaemia
4
Q
Corticosteroids cause …
A
Uraemia
5
Q
Sodium chloride (NACL)/ sodium bicarb (NAHCO) cause …
A
Sodium and water retention
6
Q
What drugs cause renal toxicity?
A
NSAIDS
Penicillin
Gold, penicillamine
7
Q
Which drugs can lower renal function?
A
NSAIDs
ACEI
Ciclosporin, aciclovir
Cpntrast media