Drugs in kidney disease Flashcards

1
Q

Which drugs are excreted by kidneys and so accumulate in the body in renal failure?

A
Digoxin
Lithium
Morphine
Pethidine 
Penicillin, gentamicin, vancomycin, erythromycin, aciclovir
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2
Q

Which drug require HIGHER doses in renal failure?

A

Furosemide

uraemia makes kidneys less sensitive to furosemide so higher doses are needed

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3
Q

Spironolactone cause …

A

Hyperkalaemia

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4
Q

Corticosteroids cause …

A

Uraemia

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5
Q

Sodium chloride (NACL)/ sodium bicarb (NAHCO) cause …

A

Sodium and water retention

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6
Q

What drugs cause renal toxicity?

A

NSAIDS
Penicillin
Gold, penicillamine

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7
Q

Which drugs can lower renal function?

A

NSAIDs
ACEI
Ciclosporin, aciclovir
Cpntrast media

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