DRUGS IN ADHD

Question 1

ATOMEXITINE;
what are important monitoring parameters for

Atomextine?

all ADHD medication?

Answer 1

appearance or worsening anxiety, depression or tics

Pulse, BP, psychiatric symptoms, appetite, weight and height should be recorded at intiatooon and following each dose adjustment then 6 monthly

Question 1

ATOMEXITINE;
What are doses?

Answer 1

Max 120mg both children and adults
based on weight

80mg maintenance

but doses above 100 in children is not licensed
doses of 120mg is not licensed

Question 2

ATOMEXITINE;
What are important risks?

Answer 2

Risk of suicidal ideal
Hepatic impiarment

Monitor for signs of both.

Question 3

LISDEXAMFETAMINE;
What are signs of overdose?

Answer 3

Amfetamines cause wakefulness, excessive activity, paranoia, hallacinations and hypertension followed by exhaustion, convulsions, hyperthermia and coma

Question 4

LISDEXAMFETAMINE;

What are important cautions?

Answer 4

Bipolar
history of CVD
Substance abuse
lower seizure threshold
psychotic disorders
susceptible to angle-close glaucoma .
tourettes

Only used in 6 yrs or older

Question 5

LISDEXAMFETAMINE;
What are monitoring requirements

Answer 5

Before initiation and after every dose change then 6monthly;
Pulse
BP
Psychiatric symtoms
weight

in children;
height

Question 6

METHYLPHENIDATE;
What is it unlicensed for?

Answer 6

Narcolepsy
ADHD in adults

Question 7

METHYLPHENIDATE;
What is the important MHRA warning?

Answer 7

Caution when switching between products due to differenced in formulations

All contain different amounts of MR and IR components, affecting frequency, amount and timing, clinical effect.

Question 8

METHYLPHENIDATE;
What are HCP to do when considering switching patients to other products?

Answer 8

Follow the specific dosage recommendations for each preparation;
discuss the reasons for switching and changes in symptoms and side-effects;
take patient preferences into account when considering a switch;
provide counselling on administration of the new preparation, especially with regards to food;
follow current clinical guidance on prescribing by brand name, or by manufacturer name if generic;
avoid frequent switching between different preparations.

Question 9

METHYLPHENIDATE:
What are cautions for ALL brands?

Answer 9

Agitation;
alcohol dependence;
anxiety;
drug dependence;
epilepsy (discontinue if increased seizure frequency);
family history of Tourette syndrome; susceptibility to angle-closure glaucoma;
tics

Question 10

METHYLPHENIDATE:
What is cautions for Concerta, Delmosart and Xaggatin?

Answer 10

Dysphagia
Restricted-intestinal lumen