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Drugs for hypertension & angina Flashcards

0
Q

Drug class of amlodipine

A

Calcium channel blocker (dihydropyridine)

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1
Q

Blood pressure goal in hypertensive patients with no comorbidities?

A

< 140/90

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2
Q

Toxicities of methyldopa

A

Hemolytic anemia, positive coombs test

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3
Q

Blood pressure goal in hypertensive patients with no comorbidities?

A

< 140/90

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4
Q

Drug class of amlodipine

A

Calcium channel blocker (dihydropyridine)

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5
Q

Drug class of nitroprusside

A

Vasodilator (parenteral)

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6
Q

Drug class of prazosin

A

Adrenergic blocker (alpha1 selective)

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7
Q

Toxicities of methyldopa

A

Hemolytic anemia, positive coombs test

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9
Q

Blood pressure goal in hypertensive patients with diabetes mellitus?

A

< 130/90

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10
Q

Drug class of losartan, valsartan, candesartan

A

Angiotensin receptor blocker (ARB)

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11
Q

Drug class of nicardipine

A

Calcium channel blocker (dihydropyridine)

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12
Q

Antihypertensive drug that can cause cyanide toxicity

A

Nitroprusside

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13
Q

Drug class of bumetanide

A

Loop diuretic

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14
Q

Drug class of methyldopa

A

CNS sympathetic outflow blocker

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16
Q

Drug class of nitroprusside

A

Vasodilator (parenteral)

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17
Q

Drug class of prazosin

A

Adrenergic blocker (alpha1 selective)

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19
Q

Drug class of fenoldopam

A

Parenteral vasodilator, dopamine agonist

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20
Q

Drug class of clonidine

A

CNS Sympathetic outflow blocker

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21
Q

Drug class of verapamil

A

Calcium channel blocker (non dihydropyridine)

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22
Q

Treatment for rebound hypertension caused by clonidine

A

Phentolamine

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23
Q

Drug class of hexamethonium

A

Sympathoplegic (ganglion blocker)

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24
Q

Drug class of hydrochlorothiazide

A

Thiazide Diuretics

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25
Q

Drug class of Reserpine

A

Sympathoplegic (nerve terminal blockers)

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27
Q

Effect of 1st dose prazosin, tamsulosin

A

Orthostatic hypotension

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28
Anti hypertensive use for pre eclampsia
Methyldopa, hydralazine
29
Drug class of propranolol
Adrenergic blocker (beta nonselective)
30
MOA of thiazide diuretic
Inhibit Na/Cl transporter in distal convoluted tubule
31
Drug class of amlodipine
Calcium channel blocker (dihydropyridine)
32
Drug class of hydralazine
Vasodilator
33
Antihypertensive drugs that are use for SVT
Verapamil
34
MOA of loop diuretic
Inhibit Na/K/2Cl transporter in thick ascending limb of loop of henle
35
Antihypertensive use for pulmonary edema
Loop diuretic (ex furosemide)
36
MOA of CNS sympathetic outflow blockers?
Activates alpha 2 adrenergic receptors
37
MOA of ganglion blockers?
Competitively blocks Nn nicotinic Ach receptors
38
MOA of nerve terminal blockers?
Irreversibly blocks the vesicular monoamine transporter (VMAT)
39
MOA of adrenergic blocker prazosin?
Selectively blocks alpha1 adrenergic receptors
40
Antihypertensive drugs that causes drug induced lupus
Oral Vasodilator (hydralazine)
41
Blood pressure goal in hypertensive patients with diabetes mellitus?
< 130/90
42
MOA of adrenergic blocker propranolol?
Blocks beta1 and beta2 receptors. Blocks sympathetic effect on heart and BP. Reduces renin release.
43
Drug class of losartan, valsartan, candesartan
Angiotensin receptor blocker (ARB)
44
MOA of non dihydropyridine CCB
Block voltage gated L type Ca+ channels (cardiac>vascular)
45
MOA of dihydropydrine CCB
Block voltage gated channel L type Ca+ channels (vascular>cardiac)
46
Drug class of minoxidil
Vasodilator
47
MOA of parenteral vasodilator
Relaxes venous arteriolar smooth muscle, activation of guanyly cyclase (release of NO)
48
Antihypertensive drugs: cough & angioedema as side effect
ACE inhibitor ("pril" family)
49
BP range of stage 1 HPN according to JNC7
140-159/90-99
50
Toxicities of nerve terminal blocker
Suicidal ideation, severe psyche depression
51
Antihypertensive contraindicated in asthmatics
Adrenergic antagonist (propranolol, timolol, carvedilol)
52
BP range of stage 2 HPN according to JNC7
>160/>100
53
Drug class of Aliskerin
Renin antagonist
54
Adrenergic blocker that is most selective for prostatic smooth muscle
Tamsulosin
55
Antihypertensive drugs that candelap progression of diabetic nephropathy
ACE inhibitor, ARB
56
Antihypertensive drugs that mask symptoms of hypoglycemia in diabetics
Adrenergic antagonist (ex. Propranolo, timolol, labetalol)
57
Antihypertensive drugs that are use for angina
dihydropyridine CCB (ex. nifedipine, nicardipine)
58
MOA of ARB
Blocks AT1 receptors in vascular smooth muscle and adrenal cortex
59
Treatment for malignat HPN
Vasodilators (nitroprusside, fenoldopam) with diuretics (furosemid) and beta blockers
60
Drug class of amyl nitrite
Ultra short acting nitrate
61
Drug class of nitroglycerin, ISDN, ISMN
Short acting nitrate
62
Drug class of captopril, enalapril
ACE inhibitor
63
Disease cause by occupational exposure to nitrates
Monday disease
64
Antihypertensive drug use for reynaud's phenomenon
Diltiazem
65
1st line drug for angina
Nitroglycerin
66
Antihypertensive drugs use for angina prophylaxis
Beta blockers
67
Treatment for cyanide poisoning
Inhaled amyl nitrite + IV sodium nitrite + IV sodium thiosulfate
68
Drug class of diltiazem
Calcium channel blocker (non dihydropyridine)
69
MOA of ACE inhibitors
Inhibits ACE to convert angiotensin I to angiotensin II. Decrease aldosterone secretion
70
Meds that causes drug induced lupus
Hydralazine, isoniazid, procainamide, penicillamine
71
Toxicities of non dihydropyridine CCB (verapamil, diltiazem)
Gingival hyperplasia, AV block
72
Drug class of nicardipine
Calcium channel blocker (dihydropyridine)
73
Antihypertensive drugs that causes hypertrichosis
Oral vasodilator (minoxidil)
74
Antihypertensive drug that can cause cyanide toxicity
Nitroprusside
75
MOA of renin antagonist
Inhibits renin to convrt angiotensinogen to angiotensin I
76
Drug class of bumetanide
Loop diuretic
77
1st line drugs for hypertension
Thiazide diuretic
78
Effects of loop diuretics
Dehydration, hypokalemia, ototoxicity, hyperuricemia
79
Drug class of methyldopa
CNS sympathetic outflow blocker
80
Effects of clonidine
Rebound hypertension, sedation
81
Blood pressure goal in hypertensive patients with chronic kidney disease?
< 130/80
86
Drug class of fenoldopam
Parenteral vasodilator, dopamine agonist
87
Drug class of clonidine
CNS Sympathetic outflow blocker
88
Drug class of verapamil
Calcium channel blocker (non dihydropyridine)
89
Treatment for rebound hypertension caused by clonidine
Phentolamine
90
Drug class of hexamethonium
Sympathoplegic (ganglion blocker)
91
Drug class of hydrochlorothiazide
Thiazide Diuretics
92
Drug class of Reserpine
Sympathoplegic (nerve terminal blockers)
94
Effect of 1st dose prazosin, tamsulosin
Orthostatic hypotension
95
Anti hypertensive use for pre eclampsia
Methyldopa, hydralazine
96
Drug class of propranolol
Adrenergic blocker (beta nonselective)
97
MOA of thiazide diuretic
Inhibit Na/Cl transporter in distal convoluted tubule
98
Drug class of amlodipine
Calcium channel blocker (dihydropyridine)
99
Drug class of hydralazine
Vasodilator
100
Antihypertensive drugs that are use for SVT
Verapamil
101
MOA of loop diuretic
Inhibit Na/K/2Cl transporter in thick ascending limb of loop of henle
102
Antihypertensive use for pulmonary edema
Loop diuretic (ex furosemide)
103
MOA of CNS sympathetic outflow blockers?
Activates alpha 2 adrenergic receptors
104
MOA of ganglion blockers?
Competitively blocks Nn nicotinic Ach receptors
105
MOA of nerve terminal blockers?
Irreversibly blocks the vesicular monoamine transporter (VMAT)
106
MOA of adrenergic blocker prazosin?
Selectively blocks alpha1 adrenergic receptors
107
Antihypertensive drugs that causes drug induced lupus
Oral Vasodilator (hydralazine)
109
MOA of adrenergic blocker propranolol?
Blocks beta1 and beta2 receptors. Blocks sympathetic effect on heart and BP. Reduces renin release.
111
MOA of non dihydropyridine CCB
Block voltage gated L type Ca+ channels (cardiac>vascular)
112
MOA of dihydropydrine CCB
Block voltage gated channel L type Ca+ channels (vascular>cardiac)
113
Drug class of minoxidil
Vasodilator
114
MOA of parenteral vasodilator
Relaxes venous arteriolar smooth muscle, activation of guanyly cyclase (release of NO)
115
Antihypertensive drugs: cough & angioedema as side effect
ACE inhibitor ("pril" family)
116
BP range of stage 1 HPN according to JNC7
140-159/90-99
117
Toxicities of nerve terminal blocker
Suicidal ideation, severe psyche depression
118
Antihypertensive contraindicated in asthmatics
Adrenergic antagonist (propranolol, timolol, carvedilol)
119
BP range of stage 2 HPN according to JNC7
>160/>100
120
Drug class of Aliskerin
Renin antagonist
121
Adrenergic blocker that is most selective for prostatic smooth muscle
Tamsulosin
122
Antihypertensive drugs that candelap progression of diabetic nephropathy
ACE inhibitor, ARB
123
Antihypertensive drugs that mask symptoms of hypoglycemia in diabetics
Adrenergic antagonist (ex. Propranolo, timolol, labetalol)
124
Antihypertensive drugs that are use for angina
dihydropyridine CCB (ex. nifedipine, nicardipine)
125
MOA of ARB
Blocks AT1 receptors in vascular smooth muscle and adrenal cortex
126
Treatment for malignat HPN
Vasodilators (nitroprusside, fenoldopam) with diuretics (furosemid) and beta blockers
127
Drug class of amyl nitrite
Ultra short acting nitrate
128
Drug class of nitroglycerin, ISDN, ISMN
Short acting nitrate
129
Drug class of captopril, enalapril
ACE inhibitor
130
Disease cause by occupational exposure to nitrates
Monday disease
131
Antihypertensive drug use for reynaud's phenomenon
Diltiazem
132
1st line drug for angina
Nitroglycerin
133
Antihypertensive drugs use for angina prophylaxis
Beta blockers
134
Treatment for cyanide poisoning
Inhaled amyl nitrite + IV sodium nitrite + IV sodium thiosulfate
135
Drug class of diltiazem
Calcium channel blocker (non dihydropyridine)
136
MOA of ACE inhibitors
Inhibits ACE to convert angiotensin I to angiotensin II. Decrease aldosterone secretion
137
Meds that causes drug induced lupus
Hydralazine, isoniazid, procainamide, penicillamine
138
Toxicities of non dihydropyridine CCB (verapamil, diltiazem)
Gingival hyperplasia, AV block
140
Antihypertensive drugs that causes hypertrichosis
Oral vasodilator (minoxidil)
142
MOA of renin antagonist
Inhibits renin to convrt angiotensinogen to angiotensin I
144
1st line drugs for hypertension
Thiazide diuretic
145
Effects of loop diuretics
Dehydration, hypokalemia, ototoxicity, hyperuricemia
147
Effects of clonidine
Rebound hypertension, sedation
148
Blood pressure goal in hypertensive patients with chronic kidney disease?
< 130/80

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