Drugs For Arrythmia

Question 0

DOC for ventricular arrythmia post myocardial infarction

Answer 0

Class IB (ex lidocaine)

Question 1

Drug class of lidocaine

Answer 1

Class 1B antiarrythmia

Question 2

Antiarrthmic class of propranolol

Answer 2

Class 2

Question 3

Toxicity of tocainide (class 1B)

Answer 3

Agranulocytosis

Question 4

Drug class of flecainide

Answer 4

Class 1C antiarrythmia

Question 5

Antiarrythmic that produces lupus like syndrome

Answer 5

Procainamide

Question 7

Class 2 acts on what phase of cardiac action potential

Answer 7

Phase 4

Question 8

Antiarrthmic class of amiodarone

Answer 8

Class 3

Question 9

Drug class of verapamil

Answer 9

Class 4

Question 10

Treatment of class IA overdose

Answer 10

Sodium lactate (to reverse drug induced arrythmia)

Question 11

Most efficacious but most toxic of all antiarrythmics

Answer 11

Amiodarone

Question 11

Manifestations of amiodarone toxicity

Answer 11

Pulmonary fibrosis, parethesia, tremors, thyroid dysfunction, corneal deposits, skin deposits

Question 13

Effects of class 1 antiarrthymics on action potential duration

Answer 13

IA: prolongs AP duration; IB:shortens; IC: no effect

Question 16

Antiarrthmic class of dofetilide

Answer 16

Class 3

Question 16

Antiarrythmic use after MI

Answer 16

Procainamide

Question 17

Antiarrythmic also use as anti malarial drug

Answer 17

Quinidine

Question 18

Antiarrthymics use for thyrotoxicosis

Answer 18

Class 2 (propranolol, metoprolol, timolol)

Question 19

Antiarrythmic that can produce cinchonism (headache, vertigo, tinnitus)

Answer 19

Quinidine

Question 20

MOA of class IA Antiarrythmics

Answer 20

Block Na+ channels, slowed conduction velocity and pacemaker activity

Question 21

Drug class of propafenone

Answer 21

Class 1C antiarrythmia

Question 21

MOA group IB Antiarrythmics

Answer 21

Reduces AP duration, selectively affects ischemic or depolarized purkinje, no effect on K+ pump

Question 22

Drug class for disopyramide

Answer 22

Class 1A antiarrythmia

Question 23

Least cardiotoxic among conventional antiarrythmics

Answer 23

Lidocaine

Question 24

Drugs that can cause agranulocytosis

Answer 24

Clozapine, co-tri, colchicine, aminopyrine, phenylbutazone, PTU, indomethacin, tocainide

Question 25

Antiarrthmic class of diltiazem

Answer 25

Class 4

Question 26

MOA of class 3 antiarrythmics

Answer 26

Prolongation of AP duration, block of K channels

Question 27

Drugs use for refractory arrythmias

Answer 27

Flecainide

Question 29

Drug class of quinidine

Answer 29

Class 1A antiarrythmia, anti malaria

Question 29

Drug use for digoxin induced arrythmia

Answer 29

Lidocaine

Question 30

Class IA acts on what phase of cardiac action potential

Answer 30

Phase 0

Question 30

DOC for paroxysmal SVT

Answer 30

Adenosine

Question 31

MOA of class 2 antiarrthymics

Answer 31

Beta adrenoceptor blocker, reduces both Na & Ca currents, slows pacemaker activity

Question 32

Drug class of procainamide

Answer 32

Class 1A antiarrythmia

Question 32

Antiarrthymic use for SVT

Answer 32

Esmolol (shortest acting beta blockers)

Question 34

Class 3 acts on what phase of cardiac action potential

Answer 34

Phase 3

Question 34

antiarrythmics that produces torsades de pointes

Answer 34

Class 3 (ECG: increase in QT interval)

Question 35

Antiarrythmics contraindicated for post MI

Answer 35

Class IC (propafenone, encainide, moricizine)

Question 37

Summary of effects on AP duration

Answer 37

1A:prolongs, 1B:shortens, 1C:no effect, 2:no effect, 3: prolongs, 4:no effect

Question 38

antiarrythmics use for tx and prophylaxis of atrial fibrillation

Answer 38

Class 3 (dofetilide, ibutilide)