Drugs for HTN

Question 1

Contraindications for BB’s in HTN?

Answer 1

dyslipidemia
asthma
diabetics (mask hypoglycemic events)

Question 2

Hypertensives with angina can use

Answer 2

CCBs

BBs

Question 3

Hypertensives with DM should use

Answer 3

ACEIs

ARBs

Question 4

Hypertensives with HF should use

Answer 4

ACEIs
ARBs
BBs

Question 5

Post-MI hypertensives should use

Answer 5

BBs

Question 6

Hypertensives with BPH should use

Answer 6

non-uroselective alpha 1 blockers

Question 7

Hypertensives with dyslipidemia should use

Answer 7

Alpha blockers
CCBs
ACEIs/ARBs

Question 8

Hypertensives with dyslipidemia should avoid

Answer 8

BBs

Thiazides

Question 9

Hypertensives with DM should avoid

Answer 9

BBs

Question 10

Direct vasodilator mainly on arterioloes

Answer 10

hydralazine

Question 11

Hydralazine dose should be adjusted in fast acetylator how?

Answer 11

Because of greater first pass effect, there will be more metabolism, lower bioavailability, less anti-HTN –> INCREASE DOSE

Question 12

Drug-induced SLE caused by what vasodilator?

Answer 12

hydralazine

Question 13

Pregnancy + HTN

Answer 13

methyldopa
hydralazine
labetalol

Question 14

DIrect vasodilator on both arterioles and venules

Answer 14

nitroprusside

Question 15

Direct vasodilator working through ATP-dependent K+ Channels causing increased K efflux –> hyperpolarization of smooth ms –> arteriolar dilation

Answer 15

minoxidil

Question 16

direct vasodilator contraindicated in diabetics

Answer 16

minoxidil

decreases insulin release

Question 17

direct vasodilator with cyanide toxicity

Answer 17

nitroprusside

Question 18

antidotes for cyanide toxicity caused by nitroprusside

Answer 18

Na thisulfate

hydroxocobalamin

Question 19

cardio drugs that causes drug-induced SLE in slow acetylators

Answer 19

hydralazine (direct vasodilator through cGMP)

procainamide (Class IA antiarrhythmic)