drugs for heart failure

Question 1

increases contractility

Answer 1

digoxin
dobutamine
milrinone

Question 2

reduces preload

Answer 2

diuretics
vasodilators
ace inhibitors

Question 3

MOA of class IA drugs

Answer 3

binds to activated sodium channels and blocks the flow of sodium ions into the cardiac myocyte (prolongs action potential)

Question 4

MOA of Class IB drugs

Answer 4

binds to both activated and inactivated sodium channels and blocks the flow of sodium ions in the cardiac myocyte (shortens action potential)

Question 5

MOA of Class IC drugs

Answer 5

binds to activated sodium channels and blocks the flow of sodium ions into the cardiac myocyte (no effect on action potential)

Question 6

MOA of class II

Answer 6

blocks beta adrenergic receptors

Question 7

MOA of class III

Answer 7

binds to potassium channels and blocks the flow of K in the myocyte (prolongs action potential)

Question 8

MOA of Class IV

Answer 8

blocks voltage gated calcium channels thereby blocking the flow of calcium into the cell