Drugs for GI Disorders Flashcards
What is the therapeutic outcome of histamine-2 receptor antagonists?
inhibits acid secretion by blocking release of HCl
USED TO TREAT PEPTIC ULCERS, GERD, AND H. PYLORI ULCERS
What would be another treatment along with histamine-2 receptor antagonists for h. pylori ulcers?
antibiotic therapy
h. pylori is a bacteria that is naturally found in the stomach that can erode the stomach lining and cause ulcers
Can histamine-2 receptor blockers be bought OTC?
YES YES YES
What is an adverse effect of histamine-2 receptor antagonists?
CNS - lethargy, depression, confusion
Who should not take histamine-2 antagonists?
older adults
When are the CNS effects of histamine-2 receptor antagonists more common?
In older adults with kidney or liver dysfunction
Should antacids be taken at the same time as histamine-2 receptor antagonists?
NO NO NO (decreases absorption)
What are some patient teaching points to promote the healing of ulcers?
no smoking
no NSAIDS (these can cause ulcers)
adequate rest and reduction of stress (promotes healing)
eat meals regularly (decreases accumulation of gastric acid)
avoid alcohol (can irritate GI tract and promote ulcers)
What is the therapeutic outcome of proton pump inhibitor?
reduces gastric acid secretion
Do proton pump inhibitors have many side effects?
NO NO NO
can cause osteoperosis with long term use
What are some key patient teaching points for administration proton pump inhibitor capsules (prilosec)?
teach them not to crush, chew, or open capsule
take in the morning before eating
How long should ulcers be treated?
4-6 weeks
When giving protonix (IV), what should the nurse monitor for?
erythema and inflammation at IV site, can be irritating to veins.
What is the therapeutic outcome of mucosal protectants?
acidic environment turns sucralfate into thick substance that will coat and protect the ulcer.
Are there many side effects for mucosal protectants?
NO NO NO
if constipation does occur increase fiber and fluids