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Pharmacognosy > Drugs For Diabetes > Flashcards

Drugs For Diabetes Flashcards

1
Q

Pre diabetic conditions

A

Sugar level in fasting is 100-125 and random level below 200

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2
Q

Type 1 diabetes

A

Destruction of beta cells of pancreas

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3
Q

Type 2

A

Insulin resistance

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4
Q

Diabetes symptoms

A

Polydepsia
Polyurea
Poly phagia
Dry mouth fatigue
Ketoacidosis

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5
Q

4 drugs used for diabetes

A

GYMNEMA
SYZYGIUM
AZADIRACHTA
MOMORDICA

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6
Q

GYMNEMA sn

A

GYMNEMA Sylvestre

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7
Q

GYMNEMA local name

A

Asclepiadaeae

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8
Q

GYMNEMA ln.

A

Gurmar

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9
Q

GYMNEMA cons.

A

Gymnemic acid
Gymnemoside
Gymnemo saponins
Tannins and mucilins…

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10
Q

Moa of GYMNEMA

A

Increase insulin secretion from pancreas
Inhibition of hormones that increases glucose form liver…

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11
Q

ADRs of GYMNEMA

A

There may be some hypoglycemia

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12
Q

Uses of GYMNEMA

A

Diabetes
Hepatic disorders
Gastric disorders

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13
Q

SYZYGIUM SN

A

SYZYGIUM Jambolanum

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14
Q

SYZYGIUM LN

A

Jamun

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15
Q

SYZYGIUM fam.

A

Myrtaceae

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16
Q

SYZYGIUM con.

A

Jamboline, Vit B. Vit C glycosides, kaemferol..

17
Q

Jamboline glycosides MOA

A

Increase insulin secretion
Block reductase enzyme

18
Q

Alkaloid jambocine and glycosides gamboline MOAs

A

Inhibition of starch conversion to sugar

19
Q

Uses of SYZYGIUM

A

Diabetes
Diarrhea
Gastric problems
Bronchitis

20
Q

AZADIRACHTA SN

A

Melia AZADIRACHTA

21
Q

LN of AZADIRACHTA

A

Neem

22
Q

AZADIRACHTA class

A

Meliaceae

23
Q

AZADIRACHTA cons.

A

Azadirachtine…

24
Q

MOA of AZADIRACHTA

A

Regeneration of beta cells
Decrease in glycosidic activity
Inhibition of serotonin effect on insulin

25
Q

ADRs.

A

Maybe the loss of fertility in men
Severe reaction in children
Vomiting, diarrhea , loss of consciousness and even death

26
Q

Uses of AZADIRACHTA

A

Use in diabetes
Sedative and anthalmentic..

27
Q

MOMORDICA

A

MOMORDICA charantia

28
Q

Local name of MOMORDICA

A

Karela

29
Q

MOMORDICA family

A

Cucurbitaceae

30
Q

Constituents of MOMORDICA

A

Charantin,
Cucurbitacin
B- carotene
Lectin…

31
Q

MOA of MOMORDICA
Role of charantin and lectin

A

Charantin increases insulin sensitivity
Lectin has insulin like activity

32
Q

Uses of MOMORDICA

A

Antidiabetic
Stomachic
Gout
Ulcer
Anthelmintic

33
Q

ADRs of MOMORDICA

A

Diarrhea
Hypoglycemia
Fever

Pharmacognosy (6 decks)

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