drugs as treatment of SZ Flashcards
what do antagonist drugs do
target transmitters - dopamine and glutamate
what’s a typical psychotic drug
well established drug
bad side affects
what’s an atypical drug
new drug
fewer side effects
example of an atypical drug
clozapine
example of a typical drug
eg Haldol
how long does it take for the drug to reduce positive symptoms
2 weeks
not as good for negative
what type of drug has less risk of Tardive disconisia
atypical
what is Tardive disconisia
innovatory body movements
lots of side affects for drugs
sex drive loss
what did Meltzer do
481SZ randomly assigned to 2 groups either given placebo or atypical antipsychotic drug
Well established drug gave significant improvements versus placebo
what did Guo find
he tested 1113 chines on 7 different psychotic drugs.
No drug was more effective than the other.
what did Hartling do
-meta análisis
-Halopedriol better for positive symptoms
-Olanzapine better for negative
how are drugs ethical
more ethical that sterilisation, suggested by Winston church hill
how are drugs unethical
unpleasant side affects, some may even need their own drugs to treat it
eg clozapine can affect white blood cells so need a blood test every other week
how is drug theory reductionist
ignores CBT
