Drugs and Their Targets Flashcards
Stage 1 alanine racemases
-(Cell Wall)
- cycloserine
- Enolpyruvate transferase
- Fosfomycin
Stage 2 D-ala-D-ala pentapeptides
-(Cell Wall)
- vancomycin
- bactoprenol lipid carrier
- bacitracin
Stage 3 transpeptidases
-(Cell Wall)
- penicillins
- cephalosporins
- monobactams
- carbapenems
Membrane component targets
-(Cell Membrane)
- Daptomycin
- Polymixin B
DNA gyrase
-(Synthesis/Metabolism of nucleic acids)
-Fluoroquinolones
RNA polymerase
-(Synthesis/Metabolism of nucleic acids)
-Rifampin
DNA
-(Synthesis/Metabolism of nucleic acids)
- Metronidazole
- Nitrofurantoin
30S Ribosome
-(Inhibiting/modifying
Protein Synthesis)
- Aminoglycosides
- Tetracyclines
50S Ribosome
-(Inhibiting/modifying
Protein Synthesis)
- Clindamycin
- Macrolides
- Chloramphenicol
- Streptogramins
Isloeucyl-tRNA-synthetase
-(Inhibiting/modifying
Protein Synthesis)
-Mupirocin
Dihydropteroate Synthase -(Modification of metabolism; folate)
-Sulfonamides
Dihydrofolate Reductase
-(Modification of metabolism; folate)
-Trimethoprim