Drugs and Their Targets Flashcards

1
Q

Stage 1 alanine racemases

-(Cell Wall)

A
  • cycloserine
  • Enolpyruvate transferase
  • Fosfomycin
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2
Q

Stage 2 D-ala-D-ala pentapeptides

-(Cell Wall)

A
  • vancomycin
  • bactoprenol lipid carrier
  • bacitracin
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3
Q

Stage 3 transpeptidases

-(Cell Wall)

A
  • penicillins
  • cephalosporins
  • monobactams
  • carbapenems
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4
Q

Membrane component targets

-(Cell Membrane)

A
  • Daptomycin

- Polymixin B

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5
Q

DNA gyrase

-(Synthesis/Metabolism of nucleic acids)

A

-Fluoroquinolones

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6
Q

RNA polymerase

-(Synthesis/Metabolism of nucleic acids)

A

-Rifampin

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7
Q

DNA

-(Synthesis/Metabolism of nucleic acids)

A
  • Metronidazole

- Nitrofurantoin

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8
Q

30S Ribosome
-(Inhibiting/modifying
Protein Synthesis)

A
  • Aminoglycosides

- Tetracyclines

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9
Q

50S Ribosome
-(Inhibiting/modifying
Protein Synthesis)

A
  • Clindamycin
  • Macrolides
  • Chloramphenicol
  • Streptogramins
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10
Q

Isloeucyl-tRNA-synthetase
-(Inhibiting/modifying
Protein Synthesis)

A

-Mupirocin

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11
Q

Dihydropteroate Synthase -(Modification of metabolism; folate)

A

-Sulfonamides

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12
Q

Dihydrofolate Reductase

-(Modification of metabolism; folate)

A

-Trimethoprim

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