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Brain and Behavior Part 2 > Drugs > Flashcards

Drugs Flashcards

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The Brain flashcards
1
Q

alpha methyldopa

A

inhibits laad to prevent dopa–> dopamine

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2
Q

carbidopa

A

inhibits laad in periphery to prevent dopa –> dopamine in tx of parkinson’s

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3
Q

bromocriptine

A

d2 agonist for parkinson’s

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4
Q

disulfuram

A

inhibits dopamine beta hydroxylase to prevent dopamine –> NE

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5
Q

reserpine

A

blocks catecholamine reuptake into vesicles via VMAT

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6
Q

bretylium

A

NE release inhibitor –> Vfib

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7
Q

guanethidine

A

NE release inhibitor –> degradation of nerve endings ->htn

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8
Q

selegiline

A

MAOBI –> parkinson’s

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9
Q

phenelzine

A

MAOA/B–> hepatotoxic

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10
Q

clorgyline

A

MAOAI

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11
Q

Deprenyl

A

MAOBI

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12
Q

cocaine

A

NE reuptake inhibitor

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13
Q

imipramine

A

TCA

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14
Q

dopamine

A

inotropic tx of shock

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15
Q

dobutamine

A

inotropic tx of chf

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16
Q

amphetamines

A

increases DA and NE release and blocks reuptake, alpha methyl group to resist MAO degradation

17
Q

fenfluramine

A

SERT inhibitor and VMAT inhibitor and serotonin releasing agent

18
Q

SSRI

A

SERT inhibitor for depression and anxiety: fluoxetine, sertraline, paroxetine, fluvoxamine, citalopram; few side effects except serotonin syndrome

19
Q

MDMA

A

reverses SERT to increase synaptic serotonin –> releaser

20
Q

busiprone

A

serotonin1a partial agonist for anxiety

21
Q

sumaptriptan

A

migraines via 5ht1d/f

22
Q

MAOI

A

tx of depression, causes serotonin syndrome

23
Q

methylphenidate

A

ritalin, blocks reuptake of DA and NE in ADHD

24
Q

atomoxetine

A

NE reuptake blocker and increases DA // non stimulant (for those with stimulant side effects)

25
Q

anxiety disorder tx

A

cbt w/extinction training, benzos (specific and social phobia), ssri’s, snri’s, atypicals, tca’s, maois

26
Q

potent D2 receptor antagonists

A

first gen haloperidol and 2nd gen risperidone, lurasidone, and aripiprazole

27
Q

weak D2 receptor antagonists

A

clozapine

28
Q

2nd generation antipsychotics receptors affected

A

D2 and 5HT2a

29
Q

SNRIs

A

venlafaxine, duloxetine, etc. blocks both serotonin and ne; side effects include serotonin symptoms + htn, tachycardai

30
Q

bupropion

A

NDRI (used for nicotine), cause insomnia, anxiety, agitation, anorexia, headache

Brain and Behavior Part 2 (6 decks)

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