Drugs Flashcards
Intoxication of what cause vertical AND horizontal nystagmus?
Treat how?
PCP
Haldol to subdue
Acidify urine to inc excretion
What are the MAO-Is?
can cause what?
Phenylzine
Tranylcypromine
Selegeline
HTN crisis when mixed w/red wine and cheese
Tell-tale symptom of opiate withdrawal?
Yawning
What is in a B52 shot?
Benadryl
Haldol
Ativan
What are the potent typical antipsychotic?
Weaker?
Haloperidol > fluphenazine
Thioridazine, Chlorpromazine
Blocking dopamine in the nigrostriatal tract causes what?
Parkinsonism and EPS
What does Buproprion treat?
Smoking cessation
Depression
Prevents weight gain
What are examples of acute dystonia?
Involuntary muscle contraction
Torticollis, oculogyric crisis, hand wringing
Serotonin Syndrome has what key feature?
Hyperreflexia
Myoclonus
+ symptoms of antipsychotics d/t what pathology’s?
Mesolimbic D2C receptors (dopamine)
How to treat TCA overdose?
Sodium bicarbonate
Dilated pupils, psychosis and tachycardia indicates what intoxication?
Cocaine
What drug has symptoms of Flashbacks?
LSD
- symptoms of anti-psychotics has what pathophys?
5-HT1 serotonin
Neuroleptic malignant hyperthermia has what key feature?
Muscle rigidity
Pt that has been taking benzo’s for awhile and suddenly presents w/seizures after not taking it for 3-4 days, what is going on?
Withdrawal
What are the 1st symptoms of alcohol withdrawal?
When do they occur?
Diastolic HTN and tachycardia
48-72 hours since last drink
SE of Trazadone?
Sleep aid, priapism
What meds treat public speaking anxiety?
Propanolol
Nadolol
Atenolol
What antipsychotic causes increased weight gain and diabetes?
Olanzapine
Quetiapine SEs?
Weight gain
QTc prolongation
Somnolence
What are the symptoms of opiate withdrawal?
Pain
N/V/D
Irritable, runny nose
Valproate has what SE?
Spina bifida
Pancreatitis
Dec platelets
Agranulocytosis
TCA side effects?
Convulsions —> seizures (antagonize GABAa)
Coma
Cardiac —> Block fast Na Channels causes QRS and QT prolongation
What is akathisia?
Treat how?
Subjective feeling of restless or urge to move
Decrease dose, benztropine
Atypical anti-psychotics have what major side effect?
QTc prolongation
EPS
What are the SSRIs?
Side effects?
Escitalopram
Sertraline
Fluoxetine
Paroxetine
Dec Libido
Delayed Ejaculation
Serotonin syndrome
What are the TCAs?
Used to treat what most often?
“Tryptilines”
Imipramine
Desipramine
Doxepin
Enuresis and Neuropathic pain
What is in a coma cocktail?
DON’T get blackout
D50
Oxygen
Naloxone
Thiamine
SE of Mirtazapine?
Appetite —> especially geriatrics
MOA of atypical antipsychotics?
Block Serotonin receptors (5HT1)