Drugs Flashcards

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1
Q

Intoxication of what cause vertical AND horizontal nystagmus?

Treat how?

A

PCP

Haldol to subdue
Acidify urine to inc excretion

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2
Q

What are the MAO-Is?

can cause what?

A

Phenylzine
Tranylcypromine
Selegeline

HTN crisis when mixed w/red wine and cheese

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3
Q

Tell-tale symptom of opiate withdrawal?

A

Yawning

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4
Q

What is in a B52 shot?

A

Benadryl
Haldol
Ativan

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5
Q

What are the potent typical antipsychotic?

Weaker?

A

Haloperidol > fluphenazine

Thioridazine, Chlorpromazine

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6
Q

Blocking dopamine in the nigrostriatal tract causes what?

A

Parkinsonism and EPS

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7
Q

What does Buproprion treat?

A

Smoking cessation
Depression
Prevents weight gain

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8
Q

What are examples of acute dystonia?

A

Involuntary muscle contraction

Torticollis, oculogyric crisis, hand wringing

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10
Q

Serotonin Syndrome has what key feature?

A

Hyperreflexia

Myoclonus

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11
Q

+ symptoms of antipsychotics d/t what pathology’s?

A

Mesolimbic D2C receptors (dopamine)

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12
Q

How to treat TCA overdose?

A

Sodium bicarbonate

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13
Q

Dilated pupils, psychosis and tachycardia indicates what intoxication?

A

Cocaine

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14
Q

What drug has symptoms of Flashbacks?

A

LSD

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15
Q
  • symptoms of anti-psychotics has what pathophys?
A

5-HT1 serotonin

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18
Q

Neuroleptic malignant hyperthermia has what key feature?

A

Muscle rigidity

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20
Q

Pt that has been taking benzo’s for awhile and suddenly presents w/seizures after not taking it for 3-4 days, what is going on?

A

Withdrawal

21
Q

What are the 1st symptoms of alcohol withdrawal?

When do they occur?

A

Diastolic HTN and tachycardia

48-72 hours since last drink

22
Q

SE of Trazadone?

A

Sleep aid, priapism

23
Q

What meds treat public speaking anxiety?

A

Propanolol
Nadolol
Atenolol

25
Q

What antipsychotic causes increased weight gain and diabetes?

A

Olanzapine

26
Q

Quetiapine SEs?

A

Weight gain
QTc prolongation
Somnolence

27
Q

What are the symptoms of opiate withdrawal?

A

Pain
N/V/D
Irritable, runny nose

28
Q

Valproate has what SE?

A

Spina bifida
Pancreatitis
Dec platelets
Agranulocytosis

29
Q

TCA side effects?

A

Convulsions —> seizures (antagonize GABAa)
Coma
Cardiac —> Block fast Na Channels causes QRS and QT prolongation

29
Q

What is akathisia?

Treat how?

A

Subjective feeling of restless or urge to move

Decrease dose, benztropine

30
Q

Atypical anti-psychotics have what major side effect?

A

QTc prolongation

EPS

31
Q

What are the SSRIs?

Side effects?

A

Escitalopram
Sertraline
Fluoxetine
Paroxetine

Dec Libido
Delayed Ejaculation
Serotonin syndrome

32
Q

What are the TCAs?

Used to treat what most often?

A

“Tryptilines”
Imipramine
Desipramine
Doxepin

Enuresis and Neuropathic pain

33
Q

What is in a coma cocktail?

A

DON’T get blackout

D50
Oxygen
Naloxone
Thiamine

35
Q

SE of Mirtazapine?

A

Appetite —> especially geriatrics

35
Q

MOA of atypical antipsychotics?

A

Block Serotonin receptors (5HT1)