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Anesthesia-RAJ > Drugs > Flashcards

Drugs Flashcards

1
Q

When a lower dose of atropine is given what happens?

A

A transient decrease in sinus rate and slowing of AV nodal conduction (AV blockade) can occur.

Response is due to blockade of presynaptic muscarinic blockade that normally inhibits ACh release. Once post synaptic muscarinic blockade is established, paradoxical increase in vagal tone resolves

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2
Q

Anticholinergics are called —–, because they block the effects of the parasympathetic nervous system.

A

Parasympatholytics

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3
Q

Atropine IV & IM

  1. Onset?
  2. Peak effect?
  3. An HR increase of 30-40% for how long?
A
  1. 1 min, 5 min
  2. 5 min, 10-20min
  3. 30min
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4
Q
  1. Approximately what percentage of diazepam is protein bound?
  2. Midazolam?
A
  1. 90%

2. > 95%

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5
Q

Midazolam IM

1. Onset?

A
  1. 15min
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6
Q

How is etomidate metabolized?

A

Rapidly hydrolyzed by the liver and excreted in the urine

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7
Q

True or False. Does etomidate change the BP, heart rate, or myocardial performance?

A

False

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8
Q

Acute hemolysis can be caused by what induction agent?

A

Etomidate

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9
Q

What drug inhibits adrenal steroidogenesis- suppressing the usual increase in plasma cortisol observed during surgery?

A

Etomidate

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10
Q

What induction drug can suppress adrenal function for up to 3 hours?

A

Etomidate

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11
Q
  1. Approximately what percentage of diazepam is protein bound?
  2. Midazolam?
A
  1. 90%

2. > 95%

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12
Q

Midazolam IM

1. Onset?

A
  1. 15min
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13
Q

How is etomidate metabolized?

A

Rapidly hydrolyzed by the liver and excreted in the urine

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14
Q

True or False. Does etomidate change the BP, heart rate, or myocardial performance?

A

False

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15
Q

Acute hemolysis can be caused by what induction agent?

A

Etomidate

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16
Q

What drug inhibits adrenal steroidogenesis- suppressing the usual increase in plasma cortisol observed during surgery?

A

Etomidate

17
Q

What induction drug can suppress adrenal function for up to 3 hours?

A

Etomidate

Anesthesia-RAJ (6 decks)

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