Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Vitamins > Drugs > Flashcards

Drugs Flashcards

1
Q

Oxacillin, Nafcillin, dicloxacillin

A

Penicillinase resistant penicillins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Piperacillin

A

beta lactamase, use for pseudomonas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

cefazolin, cephalexin

A

1st gen cephalosporins, use for protus, e coli, klepsiella

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

cefoxitin, cefaclor

A

2nd gen cephalosporins, use for Haemophilus, Enterobacter, Neisseria, Klebsiella, Serratia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Ceftriaxone

A

3rd gen cephalosporin, use for meningitis and gonorrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Cefepime

A

4rth gen cephalosporin, use for psuedomonas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

aztreonam

A

betalactamase resistant, no cross allergeicity with penicillins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Gentamicin, neomycin, Streptomycin

A

Aminoglycosides,
Bind to 30s and inhibit formation of initiation complex and mRNA misreading.
Ineffective against anaerobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Tetracycline, doxycycline

A

Tetracyclines

Bind to 30s and prevent attachment of tRNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Azithromycin, clarithromycin, erythromycin

A

macrolides

Bind to 50s and block translocation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Cloramphenicol

A

Block peptidyltransferase at 50s
Serious infections only
Causes aplastic anemia and grey baby syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Ciprofloxacin

A

Fluoroquinolones
Inhibit DNA gyrase
can cause tendon rupture, damages cartilage in fetus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Clindamycin

A

Blocks peptide transfer at 50s

treats anaerobes above the diaphragm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Metronidazole

A

Forms free radicals to damage DNA
Treats anaerobs below diaphragm
Disulfiram like reaction with alcohol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Isoniazid

A

blocks synthesis of mycolic acids

neurotoxic, hepatotoxic, can induce B6 deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Rifampin

A

inhibis DNA dependent RNA polymerase

Orange fluids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

pyrazinamide

A

Acidifies intracellular environment of TB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Ethambutol

A

decreases carbohydrate polymerization of cell wall

red green colorblind

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Amphotericin B

A

Binds ergosterol to form membrane pores

nephrotoxicity, arrhythmias, anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Azoles

A

inhibity fungal sterol synthesis by inhibiting P450

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Terbinafine

A

inhibits squalene epoxidase, use for dermatophytoses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Oseltamivir

A

Inhibits influenxa neuraminidase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

ribaviren

A

Inhibits Guanine synthesisby inhibiting inosine monophosphate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Acyclovir, Famciclovir, valayclovir

A

Guanosine analog, chain termination

Needs to be phosphorilated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Ganciclovir

A

Guanosine analog, inhibits viral DNA polymerase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Foscarnet

A

Viral DNA polymerase inhibitor

does not need to be phosphorilated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Protease inhibitors

A

Block pol gene and the cleaving of polypeptide

causes hyperglycmia

28
Q

NRTIs

A

Competitively inhibit nucleotide binding to reverse transcriptase
Cause bone marros suppression

29
Q

Efavirenz, nevirapine, delavirdine

A

NNRTIs
Bind to reverse transcriptase at allosteric site.
Causes rashes and hepatotoxicity

30
Q

Raltegravir

A

Integrase inhibitor

Causes hypercholesterolemia

31
Q

Enfuvirtide

A

Fusion inhibitor, binds to gp41

32
Q

Cyclosporine

A

Calcineurin inhibitor, prevents IL2 transcription

33
Q

Tacrolimus

A

Calcineurin inhibitor, binds FK506, prevents IL2 transcription

34
Q

Sirolimus

A

Blocks IL2 signal transduction

35
Q

Bethanechol

A

Cholinomimetic, urinary retention

36
Q

Carbachol

A

Cholinomimetic,

37
Q

Neostigmine

A

cholinesterase inhibitor

reverses neuromuscular junction blockade

38
Q

Pyridostigmine

A

anticholinesterase

myasthenia gravis

39
Q

Physostigmine

A

Anticholinesterase

Treats atropine overdose

40
Q

Atropine

A

muscarinic antagonist

treats bradycardia

41
Q

Epinephrine

A

Beta more than alpha

42
Q

Norepinephrine

A

Alpha1 > Alpha2 > Beta1

43
Q

Phenylephrine

A

Alpha 1 and 2

44
Q

Isoproterenol

A

Beta 1 and 2

45
Q

Phenoxybenzamine

A

Irreversible alpha blocker

46
Q

Phentolamine

A

Reversible alpha blocker, give to patients on MAO inhibitors who eat tyramine

47
Q

Prazosin, terazosin, doxazosin, tamulosin

A

alpha 1 blockers

48
Q

Mirtazapine

A

Alpha 2 blocker

49
Q

Carvedilol, labetalol

A

nonselective alpha and beta antagonists

50
Q

Statins

A

Lower cholesterol, inhibits HMG CoA

51
Q

Niacin

A

Inhibits lipolysis in adipose tissue, reduces hepatic VLDL synthesis
causes itching and gout

52
Q

Bile acid resins

A

prevent reabsorption of bile acids

increases Trigs, forms gallstones

53
Q

Ezetimibe

A

Cholesterol absorption blocker

54
Q

Fibrates

A

Upregulate LPL causing TG clearance
Activates PPAR alpha to induce HDL
Causes gallstones

55
Q

Metformin

A

acts on liver pushing towards glycolysis

Lactic acidosis

56
Q

Sulfonylureas

A

close K channel to depolarize cell, triggering insulin release via Ca influx

57
Q

Glitazone

A

Increae peripheral insulin sensitivity by binding to PPAR gamma

58
Q

Cilostazol, dipyridamole

A

PDE III inhibitor, inhibits platelet aggregation and causes vasodilation

59
Q

Bisphosphonates

A

Bind to hydroxyapatite in bone inhibiting osteoclasts

60
Q

Sumatriptan

A

Blocks 5 HT to inhibit CN V prophylaxis for migranes

61
Q

Lithium

A

Mood stabilizer

Terratigin, hypothyroidism,

62
Q

Mannitol

A

osmotic diuretic

causes pulmonary edema

63
Q

Furosimide

A

Block Na/K/2Cl pump

causes ototoxicity, hypokalemia, nephritis and gout

64
Q

HCTZ

A

Inhhibits NaCl reabsorption

hypokalemic metabolic acidosis, hyponatremia, hyper everything else

65
Q

Montelukast, zafirlukast

A

Blocks leukotriene receptor

66
Q

Zileuton

A

blocks 5 lipoxygenase

Vitamins (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions