Drugs Flashcards
Ferrous sulfate
Used to treat iron deficiency anemia
What are is the most common and the dangerous side effect of metformin? Contraindications?
Diarrhea is most common. Lactic acidosis. Contradicted in renal disease.
Dexlansoprazole (Dexilant)
PPI, often used as second line
Common side effects of SSRIs & SNRIs?
Headaches. Sleep disturbances–drowsiness and, less frequently, insomnia, and gastrointestinal problems such as nausea and diarrhea.
They can also cause hyponatremia, due to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH); serotonin syndrome, and an increased risk of gastrointestinal bleeding.
Fluoxetine (Prozac)
Unusually long half life (two to four days), so effects can last for weeks after discontinuation. Most problematic (but uncommon) side effects include agitation, motor restlessness, decreased libido in women, and insomnia.
Sertraline (Zoloft)
In addition to being a frequently used SSRI in pregnancy and breastfeeding, approved specifically for obsessive-compulsive, panic, and posttraumatic stress disorders.
More gastrointestinal side effects than the other SSRIs.
Paroxetine (Paxil)
Strong antianxiety effects.
Best studied SSRI in children.
Side effects can include significant weight gain, impotence, sedation, and constipation.
Due to its short half-life, paroxetine is most likely of all the SSRIs to cause antidepressant discontinuation syndrome
Fluvoxamine (Luvox)
Particularly useful in obsessive-compulsive disorder.
Greater frequency of emesis compared to other SSRIs.
Escitalopram (Lexapro)
Approved specifically for Generalized Anxiety Disorder.
Overall, fewer side effects than citalopram.
Treatment for uncomplicated cystitis?
Bactrim (TMP-SMX) 3 days
PrEP (Truvada)
tenofovir 300/ emtricitibine 200 once daily. Pre-exposure prophylaxis. Can reduce kidney function –> check twice a year
Testosterone therapy?
Should be IM or transdermal. DO NOT give oral testosterone, this increases risk of liver cancer
