Drugs

Question 1

sildenafil

Answer 1

Viagra

PDE5 inhibitor= inhibits the degradation of cGMP

Question 2

tadalafil

Answer 2

Cialis

PDE5 inhibitor

Question 3

vardenafil

Answer 3

Levitra

PDE5 inhibitor

Question 4

clomiphene citrate

Answer 4

Clomid, Serophene
nonsteroidal estrogen receptor modulator; blocks feedback inhibition of hypothalamus
used for infertility in anovulatory women
clomiphene failure= no pregnancy w/in 6 cycles

Question 5

letrozole

Answer 5

Femara

aromatase inhibitor= decrease in estrogen results in increase in release of FSH and LH

Question 6

Gonadotropin therapy examples

Answer 6

Repronex, Menopur, Bravelle, Gonal-f, Follistim AQ, Luveris

Question 7

gonadorelin

Answer 7

Lutrepulse
synthetic GnRH
matches more closely to natural system with minimal monitoring but it is expensive

Question 8

GnRH agonists

Answer 8

“-relin”
longer half lives than native GnRH
reduce # of oocytes released prematurely
TAKES A FEW WEEKS TO TAKE EFFECT

Question 9

GnRH antagonists

Answer 9

“-relix”
prevent premature LH surge
DO NOT have initial flare stage

Question 10

hCG brand names

Answer 10

Pregnyl, Novarel, Ovidrel

useful as ADDITIVE therapy

Question 11

Dopamine agonists

Answer 11

bromocriptine, cabergoline

used in hyperprolactinemia

Question 12

Divigel administration

Answer 12

left or right upper thigh

Question 13

EstroGel administration

Answer 13

arm

allow to dry for up to 5 min before dressing

Question 14

Elestrin administration

Answer 14

upper arm and shoulder

Question 15

Estrasorb adminstration

Answer 15

on each leg (thigh and calf)

excess material should be rubbed into the buttocks

Question 16

Evamist administration

Answer 16

inner forearm