Drugs Flashcards

1
Q

Define Psychoactive Drugs

A

Drugs or other substances that act upon the Central Nervous System and effect brain functions including – perception, moods, thinking and behavior are altered

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2
Q

What are the legal psychoactive drugs?

A

Caffeine: Found in coffee, tea, and energy drinks, it’s a widely consumed stimulant.

Nicotine: Present in tobacco products, though its use is heavily regulated.

Alcohol: A depressant that’s legal for adults over 21.

Cannabis: Legal for medical or recreational use in many states, though still federally restricted.

Kratom: A plant-based substance legal in some states, often used for its stimulant or sedative effects.

Kava: A root-based drink known for its calming effects, legal in most places.

Dextromethorphan: Found in cough syrups, it can have psychoactive effects in high doses.

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3
Q

What are examples of psychoactive drugs?

A

Psychoactive drugs are substances that affect the brain and alter mood, perception, or behavior. Examples include:

Caffeine: Found in coffee, tea, and energy drinks.

Alcohol: A depressant widely consumed in beverages.

Nicotine: Present in tobacco products.

Cannabis: Used recreationally or medicinally in many places.

Antidepressants: Like SSRIs, prescribed for mental health conditions.

Stimulants: Such as amphetamines, often used to treat ADHD.

Hallucinogens: Like LSD or psilocybin (magic mushrooms).

Opioids: Such as morphine or codeine, used for pain relief.

Some are legal and regulated, while others are controlled or illegal.

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4
Q

What are some effects of psychoactive drugs?

A

Psychoactive drugs interact with the brain and central nervous system to alter mood, perception, cognition, and behavior. Here’s a general overview of their effects:

  • Stimulants (e.g., caffeine, nicotine, amphetamines): Increase alertness, energy, and focus. They can also elevate heart rate and blood pressure.
  • Depressants (e.g., alcohol, benzodiazepines): Slow down brain activity, leading to relaxation, reduced anxiety, and drowsiness. Overuse can impair coordination and judgment.
  • Opioids (e.g., morphine, oxycodone): Relieve pain and induce euphoria, but carry a high risk of dependence and respiratory depression.
  • Hallucinogens/ psychedelics (e.g., LSD, psilocybin): Distort perception and can cause vivid visual and auditory hallucinations. They might also lead to changes in thought patterns or emotions.
  • Cannabis: Can produce relaxation, mild euphoria, and altered sensory perception. Some users may experience paranoia or anxiety.
  • Antidepressants or mood stabilizers: Aim to improve mood and emotional balance for those with specific mental health conditions. They usually have subtler, long-term effects.

These effects can vary based on the substance, dosage, individual physiology, and environment.

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5
Q

What are Hallucinogens?

A

Drugs that alter perceptions of the external environment and inner awareness – induce sensory and perceptual distortions; skewed sense of time. Do not appear to have the same potential for abuse as other drugs

They distort perceptions, alter mood and thinking

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6
Q

List some Hallucinogens

A

Marijuana

LSD (lysergic acid diethylamide): SA agonist

Mescaline: SA agonist

PCP (Phencyclidine) : aka angle dust

Ketamine : (anesthetic for animals)

Plant base: Peyote, Psilocybin

MDMA (Ectasy)

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7
Q

What are the effects of using LSD (lysergic acid diethylamide)

A

LSD can produce psychotic reactions, especially in people who are psychologically unstable.

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8
Q

Who discovered LSD (lysergic acid diethylamide)

A

Albert Hofmann, a Swiss chemist

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9
Q

What did Hofmann’s team do?

A
  • Hofmann’s team isolated, named and synthesized the principal psychedelic mushroom compounds psilocybin and psilocin.
  • The first to synthesize, ingest, and learn of the psychedelic effects of lysergic acid diethylamide (LSD).
  • He spent years investigatingLSD’s hallucinogenic propertiesin the belief that the drug would one day be useful in the therapeutic treatment of schizophrenics and other psychiatric patients.
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10
Q

What are the effects of alcohol and other depressants

A
  • Suppress or decrease central nervous system activity– slow down the body’s physiological and mental processes
  • Approximately 16 million Americans are physically dependent upon or abuse alcohol
  • These drugs serve as agonists of the GABA neurotransmitter system, has a quieting effect on the brain
  • These types of drugs are often prescribed to treat Anxiety, muscle spasms, seizures, and insomnia
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11
Q

Name some depressants

A

Alcohol
Barbiturates
Benzodiazepines
Inhalants
Tranquilizers

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12
Q

What does alcohol cause?

A
  • Feelings of Euphoria
  • Feelings of sedation
  • Decrease reaction
  • Lowers alertness
  • Loss of balance/coordination
  • Reduces behavioral control
  • Fetal alcohol spectrum syndrome
  • Fetal alcohol syndrome
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13
Q

What do stimulants do?

A

Excite or increase overall levels of neural activity and speed up physiological and mental processes

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14
Q

Name some stimulants

A
  • Caffeine
  • Nicotine
  • Amphetamines (Adderall, Dexedrine)
  • Methamphetamines
  • Cocaine
  • Methcathinones
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15
Q

What do stimulants do?

A
  • Euphoria (euphoric high)
  • Feeling of intense pleasure
  • Feeling alert

Repeated use = adverse effects:
* Anxiety, headaches, insomnia
* Nausea, hallucinations, paranoia
* Elevated heart rate and blood pressure
* Altered brain functions
* Many of these drugs act as agonists of the DA neurotransmitter system; blocking the reuptake in the neuronal synapse (cocaine) and or/stimulating its release (amphetamines)

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16
Q

What are the effects of caffeine

A
  • Most commonly used stimulant
  • High levels: insomnia, agitation, muscle twitching, nausea, arrhythmia, death
17
Q

*

What are the effects of nicotine?

A
  • Legal use of nicotine generates many more deaths and much more public health spending than all other drugs combined (including alcohol).
  • Highly addictive
  • Increased heart disease, stroke, varied cancers
  • Used widely and publicly contributes to the impression that it is not really a drug.
  • Agonizes Ach and other neurotransmitter systems.
18
Q

What are Opioids?

A
  • Analgesic properties to relieve pain, suppress cough; produce feelings of euphoria
  • Drugs/narcotics that suppress pain and response to stimulation and mimic the brain’s endorphins
19
Q

Name the differnt types of Opioids

A
  • Opium (Natural Opioid)
  • Synthetic:
    Methadone
    Fentanyl
  • Semi- Synthetic Opioids:
    Morphine
    Heroin (euphoria to agitation)
    Codeine
    Hydrocodone
    Oxycodone
20
Q

What is the major issues with psychoactive drugs?

A

Some psychoactive drugs are highly addictive - psychological and physical

21
Q

What is Drug Abuse?

A

Inappropriate recurrent use of a drug or drugs that results in physical, mental, emotional or social impairment – creates a disruption in academic, social, or occupational functioning and/or create legal or psychological problems

22
Q

What is a Psychological dependence and addiction?

A

An emotional need that is independent of physical need; often feel they cannot function without continued use to relieve stress, for example.

23
Q

What are the effects of Physical dependence and addiction?

A

Changes in normal body functions that occur after repeated use. User will experience withdrawal from the drug upon cessation of use.

24
Q

What is Tolerance?

A

Tolerance is linked to physiological dependence; reduced effectiveness after repeated use

25
Define **Addiction**
Addiction is compulsive drug craving and use, and when using a drug becomes the most important activity in the user’s life despite adverse consequences; body becomes dependent on the drug and goes through withdrawal when the body lacks the drug.
26
What is **Withdrawal Syndrome**?
Elimination or decrease use of an addictive drug lead to **Withdrawal syndrome** – negative symptoms when drug is discontinued – can range from mildly unpleasant to life-threatening (elimination or decreased use of an addictive drug)
27
What is **Substance Abuse Disorder** ?
**Substance abuse disorder** is the use of a prescribed medication beyond the original intent – and continued use despite adverse consequences – physical and psychological dependence
28
How do addictive drugs affect the brain?
* Almost all euphoric drugs work through the dopamine system * If a drug produces euphoria, it has the potential to be abused * Heroine, cocaine, amphetamines, alcohol and nicotine – all affect levels of dopamine
29
What happens to the **brain's dopamine (DA) system** of a person who uses addictive drugs?
* The brain’s dopamine (DA) system adapts to the high levels of dopamine produced by the use of the addictive drug. * Long-term methamphetamine use can produce damage to the brain’s dopamine system, which is associated with memory and motor skill problems, and the frontal lobes, which can lead to impairment in cognitive and social skills. * Agonists of the DA system * Cocaine and Amphetamines block reuptake and stimulate the release of DA
30
What is a psychological effect of the physical changes as a result of addiction to alcohol, heroin, cocaine, or amphetamines?
Positive events in normal life are no longer reinforcing or satisfying
31
What are the effects of drug abuse on the **brain**?
Different abused drugs increase DA levels in the brain’s reward system – initial intoxicating effect. Over time: * the brain adjusts to the effects of drug abuse * causes long-term changes in the brain’s circuitry * number of DA receptors in brain’s reward system reduced.
32
What are the different **influences of drug use**?
**Biological Influences** * Genetic predispositions * Variations in neurotransmitter systems **Psychological Influences** * Lacking sense of purpose * Significant stress * Psychological disorders, such as depression **Social-cultural Influences** * Urban environment * Cultural attitude toward drug use * Peer influences
32
What is **Substance Use Disorder**?
Continued use of drug continues despite significant life disruption. Resulting brain changes may persist after quitting use of the substance (thus, leading to strong cravings when exposed to people and situations that trigger memories of drug use. The severity of substance use disorder varies from mild to severe. Resulting in: * Diminished control * Diminished social control * Hazardous use * Drug action