Drugs

Question 1

What is the adult dose of Hydrocortisone?

Answer 1

100mg

Question 2

How much water for injection should the Hydrocortisone carried by WMAS be diluted in?

Answer 2

Up to 2 ml

Question 3

What are the indications for hydrocortisone

Answer 3

Severe life threatening asthma

Acute exacerbation of COPD

Adrenal crisis (Addisons)

Prevention of adrenal crisis in a patient who has suffered traumatic injury and is also on a programme of long term steroid therapy

Pregnant women with known diagnosis of Addisons who are in active labour.

Question 4

What is the repeat dose for hydrocortisone?

Answer 4

None

Hydrocortisone is a single 100mg dose

Question 5

What drug can we give for Cocaine toxicity and what are the indications?

Answer 5

Diazepam

Known cocaine use with chest pain, severe Hypertension (>220 systolic >140 diastolic) or convulsions

Question 6

Adult dose of salbutamol (neb)

Answer 6

5mg in 2.5ml

Repeat every 5 minutes as required

Question 7

Adult dose Ipratropium Bromide (neb)

Answer 7

500mcg in 2ml (no repeat dose)

Question 8

Adult dose of Magnesium Sulphite

Answer 8

2mg (No repeat dose)

Question 9

Adult Dose of Hydrocortisone (Asthma and COPD exacerbation)

Answer 9

100mg in 2ml of H2O (No repeat dose)

Question 10

IV Paracetamol 12yo- Adult (more than 50kg) dose

Answer 10

1g in 100ml

Question 11

PO Paracetamol for Pt weighing less than 50kg

Answer 11

750mg

Question 12

What is the dose for GTN for a suspected ACS patient?

Answer 12

400-800micrograms (mcg) every 5-10 minutes with NO maximum dose.

In ?ACS Sys BP > 90mmHg

Question 13

What is the Adult Dose of Morphine Sulphate?

Answer 13

10mg,

5 minute interval,

repeat dose 10mg,

Maximum dose 20mg

Question 14

What is the Adult dose of Aspirin for a suspected ACS patient?

Answer 14

300mg

Question 15

Can you administer aspirin to a Patient who is <16 YO?

Answer 15

No as there is a risk of Reyes disease.

Question 16

When should adrenaline 1 in 10,000 be given in cardiac arrest? (Adult)

Answer 16

Non shockable rhythm- administer 1mg (10ml) as soon as IV access achieved

Shockable rhythm - after the 3rd and 5th shock followed by every alternative shock.

Question 17

Diazepam indications

Answer 17

Active convulsions, seizures lasting >5minutes, Eclamptic pregnant mothers with seizures lasting >2-3 minutes. Cocaine toxicity (with chest pain and severe hypertension/ seizures)

Question 18

Diazepam (IV/IO) dose

Answer 18

10mg in 2ml

Question 19

Diazepam (IV/IO) interval and repeat dose

Answer 19

10 minutes

10mg in 2ml

Question 20

Diazepam Max Dose (IV/IO)

Answer 20

20mg

Question 21

Diazepam Actions

Answer 21

Diazepam binds to the benzodiazepine receptors on the chloride channels in the membrane of neurones causing the channel to open allowing chloride ions to enter (Cl-). The refractory period of the neurone is increased) causes the neurone to be unable to reach threshold potential inhibiting signals.

Question 22

What is Atropine Sulphate used to treat?

Answer 22

Absolute bradycardia and AV block

Question 23

Actions of Atropine Sulphate

Answer 23

Atropine is an acetylcholine antagonist that prevents action potentials crossing synaptic clefts in the vagus nerve reversing vagal overdrive, allowing the SA node to produce an intrinsic depolarising rate. Also increases conductivity of the AV node in AV block.

Question 24

What is the Dose of Atropine Sulphate

Answer 24

600Mcg in 1ml

Question 25

What is the dosage interval in Atropine Sulphate?

Answer 25

3-5 minutes

Question 26

What is the Max dose of Atropine Sulphate?

Answer 26

3Mg