Drugs

Question 1

Growth Hormone Mechanism

Answer 1

• binds to membrane receptor
• activates cytoplasmic tyrosine kinase (JAK2) which phosphorylates several protein involved in signaling pathways leading to different effects in different specific cell types
• anabolic and growth-promoting effects are mediated though IGF-1 and IGF-2

Question 2

Samatropin

Answer 2

-all growth hormone that is identical with hGh

Question 3

corticotropin

Answer 3

• ACTH

- stimulates adrenal gland hormone production (esp cortisol)

Question 4

Octreotide

Answer 4

• treatment growth hormone excess

- for gigantism and acromegaly

Question 5

Carbergoline

Answer 5

-dopamine receptor agonist to decrease prolactin

Question 6

Menotropin

Answer 6

• urine from postmenopausal women that contains FSH and LH
• IM administration
• used in women for the treatment of infertility

Question 7

Ganirelix

Answer 7

• decapeptide GnRh receptor antagonists
• used in in vitro fertilization
• delay premature LH surge
• delays ovulation to allow collection of ova (controlled ovarian hyperstimulation) follows FSH therapy

Question 8

Cetrorelix

Answer 8

• decapeptide GnRh receptor antagonists
• used in in vitro fertilization
• delay premature LH surge
• delays ovulation to allow collection of ova (controlled ovarian hyperstimulation) follows FSH therapy