Drugs

Question 1

Acetazolamide

Answer 1

Inhibit carbonic anhydrase.

Used to treat:
Glaucoma
Edema from HF
Epilepsies

Question 2

Timolol

Answer 2

Non-selective Beta blocker.
Beta-1 in heart, Beta-2 in the vascular and bronchial muscle.

Treats:
Increased Intraocular pressure

Question 3

Mannitol

Answer 3

Sugar alcohol.
Osomotic Diuresis.

Question 4

Propofol

Answer 4

General anesthesia and sedation.
Positive modulation of GABA.

Also used for seizures over 5mins.

Question 5

Donepezil

Answer 5

Acetylcholinesterase inhibitor.

Treats:
Dementia.

Question 6

Suxamethonium

Succinylcholine

Answer 6

Found on post-synaptic cholinergic receptors.
Prolonging membrane depolarization.

Skeletal muscle relaxation.
used in surgery/tracheal intubation.

Question 7

Isoflurane

Answer 7

Decreases gap junction opening times and increasing the closing time, reducing conductance.

Inhaled general anesthetic for surgery.

Question 8

Atracurium

Answer 8

Neuromuscular block.
Relaxes muscles during mechanical ventilation.

Competively blocks cholinergic receptors.

Question 9

Fentanyl

Answer 9

Mu opioid receptor agonist.

Question 10

Phenobarbital

Answer 10

Act on GABAA receptors, increasing synaptic inhibition.

Question 11

Sodium Valproate

Answer 11

Inhibits succinic semialdehyde dehydrogenase, increases succinic semialdehyde which inhibits GABA metabolism.

Used:
Seziures.
Prophylaxis migraine.
Biopolar disorder.

Question 12

Lithium

Answer 12

Stimulates NMDA receptor.

Mood stablizer.

Bipolar disorder.
Depression.

Question 13

Diazepam

Answer 13

Increases inhibitory effects of GABA on various regions of body.

Anxiety.
Alcohol withdraw.
Refractory Epilepsy (refractory = non responsive to treatment).

Question 14

Lamotrigine

Answer 14

Voltage-sensitive sodium channels, thereby modulating release of excitatory neurotransmitters.

Seizures.

Question 15

Carbamazepine

Answer 15

Anti Convulsant.
Inhibits sodium channel firing.

Trigeminal neuralgia.

Question 16

Phenytoin

Answer 16

Prophylaxis Anti convulsant.
Non-specific sodium channel blocker.

Epilepsy.

Question 17

Gabapentin

Answer 17

a1g2 subunit on voltage gated CALCIUM channels.

Peripheral neuropathic pain.
Postherpetic neuralgia.
Partial-onset seizure.

Question 18

Azathioprine

Answer 18

Immunosuppresant.
Inhibition of purine synthesis & B/T cells.

Renal transplant rejection.
Rheumatoid Arthrtitis.
Crohns Disease.