drugs

Question 1

rompun

Answer 1

xylazine hydrochloride
stimulates alpha 2 adrenergic receptors
best effect 15-20 mins, duration of analgesia 15-30mins
causes drop in BP + temp
if overdose = respiratory and circulatory depression
contraindication = exhaustion, liver/kidney damage, stress
antidote = anti sedan

Question 2

xylazine HCL injection

Answer 2

• for use in cervidae: fallow deer, mule deer
• sedative, analgesic and muscle relaxant
• 10-15 mins IM in horses and cervidae within 3-5 mins
• 1-2 hrs and analgesic 15-30mins
• xylazineHCL, decreases HR
• side effects: muscle tremors, bradycardia
• precautions: depressed respiration, heart disease… shock
• don’t use in conjunction with transuqilisers
• if animal has been underused, advisable to wait 1hr before readminsteration
• shouldn’t be used on domestic food-producing animals

Question 3

ketamine hydrochloride

Answer 3

• rapid acting dissociative drug
• profound analgesia
• respiratory distress
• contraindications: ketamine hydrochloride

Question 4

zoletil

Answer 4

• solid analgesia and rapid cataleptic anaesthesia, sedation
• induction: 3-5 min and full action 10-15min
• hypersalivation, hypertension
• combine with atropine sulphate, rompun
• contraindication: damage to heart and respiratory system
• antidote: flumazenil, antisisedan

Question 5

domosedan

Answer 5

• IM, IV slow
• agonist of alpha two adrenergic receptor
• slows heart rate
• induction 2-19min, full action 15-30min
• hyperglycaemia and frequent urination with IV
• avoid contact with skin and MM, starve animals 12 hrs prior to administration
• antidote: at overdose, atropine

Question 6

domitor

Answer 6

• IM, SC, IV
• alpha2 adrenergic receptor
• 15-30 min
• causes bradycardia, bradypnea, AV block
• combine: pre med: thiopentone
• contraindication: pregnant,y sympathomimetics
• antidotes: antisedane

Question 7

sedaline

Answer 7

• IM, IV, SC
• fast - IM, SC, 15-20 mins small animals
• 30-60min large
• IV 5 min small
• sedation for 6-12 hrs, calming
• consciousness remains preserved
• bradypnea, tachycardia, hypotension
• contraindications: severe anaemia, shock

Question 8

antisedan

Answer 8

• promotes release of noradrenaline, rapid resorption of IM - full action 10-15 min
• application 15-60min after domitor
• after domitor, transient hypertension
• overdose: reversible hyperactivity
• contraindication: cachexia