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Infectious diseases > Drugs > Flashcards

Drugs Flashcards

1
Q

Giardiasis

A

metronidazole

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2
Q

Legionnaires’ disease

A

erythromycin

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3
Q

skin infection - Staphylococcus aureus

A

flucloxacillin

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4
Q

Quinolones MOA

A

inhibit bacterial DNA gyrase, inhibits replication and ability to repair DNA

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5
Q

What are the side effects of quinolones?

A

rash
nausea
dizziness
headache
seizures

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6
Q

Give 2 examples of quinolones?

A

Ciprofloxacin
Levofloxacin

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7
Q

Rifamycins MOA

A

Inhibits bacterial
RNA polymerase, so RNA
transcription is prevented

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8
Q

What are the side effects of Rifamycins?

A

nausea
P450 enzyme induction (
increased drug free periods: oral contraceptives, warfarin,
phenytoin, etc.)
orange tears
sweat
urine

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9
Q

Give 2 examples of Rifamycins

A

rifamycin
rifampicin

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10
Q

Sulphonamide MOA

A

Doesn’t kill bacteria but stops replication and growth

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11
Q

What are the side effects of sulphonamide?

A

Lethargy
Anorexia
Nausea

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12
Q

Give 2 examples of Sulphonamide

A

sulfamethoxazole
trimethoprim

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13
Q

5-Nitroimidazoles MOA

A

nitro group is reduced to produce chemically reactive intermediates that inhibit DNA synthesis as well as damage existing DNA.

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14
Q

What are the side effects of 5-Nitroimidazoles?

A

Dry mouth
Vomiting

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15
Q

Give 2 examples of 5-Nitroimidazoles

A

metronidazole
tinidazole

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Infectious diseases (11 decks)

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