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Pharmacodynamics > Drugs > Flashcards

Drugs Flashcards

1
Q

Cetirizine

A

H1 receptor antagonist
Receptors: skin, blood vessels, CNS, bronchi
used to reverse or prevent itching, vasodilation, nausea, and bronchoconstriction

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2
Q

Promethiazine

A

H1 receptor antagonist
Receptors: skin, blood vessels, CNS, bronchi
used to reverse or prevent itching, vasodilation, nausea, and bronchoconstriction

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3
Q

Ranitidine

A

H2 receptor antagonists
Receptors located in parietal cells of stomach
Reduce gastric acid secretion

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4
Q

Sumatriptan

A

5-HT 1B and 1D agonist
Receptors: cerebral blood vessels
prevent dilation of cerebral blood vessels in treatment or prevention of migraine

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5
Q

Ondansetron

A

5-HT3 antagonists
Receptor: stomach and chemoreceptor trigger zone
treat or prevent nausea/emesis during chemotherapy

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6
Q

Salbutamol

A

Selective B2- receptor

Bronchodilation

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7
Q

Beta-blockers

A

Prevent beta1-receptors on the heart from being overly stimulated by endogenous adrenaline and noradrenaline

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8
Q

Naloxone

A

Competitive Opioid antagonist

Displaces the opioid at the opioid receptors and reverse the effects

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9
Q

Buprenorphine

A

Analgesia - opioid receptors
Partial agonist - has a ceiling effect
Difficult to overdose on

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10
Q

Morphine

A

‘gold standard’
opioid agonist
Range of dose forms

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11
Q

codeine

A

opioid agonists

analgesia, cough suppression, anti-diarrhoeal agent

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12
Q

methadone

A

opioid agonist

long half-life

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13
Q

fentanyl

A

analgesia - acute pain
opioid agonist
fast onset, very potent

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14
Q

Naloxone

A

Competitive opioid antagonist

reversal of opioid overdose

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15
Q

Tramadol

A

weak opioid agonist
inhibits noradrenaline reuptake and stimulation of seretonin release
less constipation and resp effects

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16
Q

furosemide

A

loop diuretic
reduces sodium reabsorption
risk of hypokalaemia

17
Q

bendrofluazide

A

thiazide diuretic

hypokalaemia, increase glucose and uric acid

18
Q

Amiloride

A

potassium sparing diuretic
hyperkalaemia
caution with ACE inhibitors + other drugs that retain potassium

19
Q

felodipine

A

CCB
block calcium channel inhibiting or reducing smooth muscle contraction in the heart and blood vessels
vasodilation
Angina and HTN

20
Q

amlodopine

A

CCB
block calcium channel inhibiting or reducing smooth muscle contraction in the heart and blood vessels
vasodilation
Angina and HTN

21
Q

Verapamil

A

CCB
block calcium channel inhibiting or reducing smooth muscle contraction in the heart and blood vessels
vasodilation, reduce myocardial activity
Angina and HTN

22
Q

Penicllin

A

Beta-lactam ring
Cell wall inhibitor - prevent transpeptidation by inhibiting the enzymes that cause peptidoglycan units to cross-link in the cell wall matrix

Pharmacodynamics (9 decks)

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