drugs Flashcards
Salbutamol indicators
Asthma, severe anaphylaxis, COPD
Salbutamol patho
Stimulates beta adrenergic cells to relax the smooth muscle and open up the airways
Ipratropium bromide indicators
Respiratory distress, bronchospasm, exacerbation of COPD
Ipratropium bromide patho
Causes bronchodilation by blocking cholinergic receptors, which causes a decrease in contraction of the smooth muscles
Dexamethasone indicators
Bronchospasm, moderate-severe croup, exacerbation of COPD, adult stridor
Dexamethasone patho
Relieves inflammatory reactions by suppressing mediators
Adrenaline indicators
Cardiac arrest, inadequate perfusion, bradycardia with poor perfusion, anaphylaxis, severe asthma, croup
Adrenaline contraindicators
Hypovolaemic shock
Adrenaline patho
Alpha and beta adrenergic stimulant which means it causes a sympathetic NS response including vasoconstriction and an increase in heart rate
GTN indicators
Chest pain with ACS, acute LVF, hypertension ACS, autonomic dysreflexia, preterm labour
GTN contraindicators
- Hypersensitivity
- Systolic BP <110 mmHg tablet
- Systolic BP <90 mmHg patch
- Sex performance drugs (viagra, levitra, cilias)
- Heart rate >150bpm
- Bradycardia <50bpm
- VT
- Inferior STEMI BP <160bpm
- Right ventricular MI
GTN patho
Causes dilation of the veins, causing pooling in the veins which reduces the amount of venous return to the heart. This reduces preload. Also causes dilation of the arteries, reducing arterial pressure and therefore afterload. Preload is the hearts opening and filling, afterload is the force of contraction
Aspirin indicators
ACS
Aspirin contraindicators
Hypersensitivity, active bleeding peptic ulcers, bleeding disorders, suspected dissecting aortic aneurysm, chest pain associated with psychostimulants
Aspirin patho
Anticoagulant, thins the blood and makes it less sticky. Prevents clots from growing bigger, minimises platelet formation.
Midazolam indicators
- Status epilepticus
- sedation to maintain intubation
- sedation to facilitate intubation
- sedation to facilitate synchronised cardioversion
- sedation to facilitate transthoracic pacing
6 sedation in the agitated patient - sedation in psychostimulant OD
Midazolam patho
CNS depressant, increases the release of GABA
Salbutamol presentation
5mg in 2.5mL