all Flashcards
asthma patho
Allergen is inhaled and causes an inflammatory response in the lower airways. Mast cells release histamine which causes bronchoconstriction, mucosal oedema.
asthma signs/symptoms
SOB, increased WOB, cough, wheeze, accessory muscle use
asthma drugs used
Salbutamol, ipratropium bromide, dexamethasone, adrenaline
asthma tx adult mild/moderate
Salbutamol in pMDI + spacer, 4-12 doses, 4 breaths per dose, repeat 20 minutes.
asthma tx adult severe
Salbutamol 10mg (5mL) nebulised, ipratropium bromide 500mcg (2mL) nebulised. Repeat salbutamol 5mg (2.5mL) every 5 minutes.
Dexamethasone 8mg IV/oral
Adrenaline 500mcg IM, repeat 5-10 minute intervals, max 1.5mg (3 doses)
COPD patho
Group of respiratory disorders characterised by increased mucous production and secretion, airway inflammation and reduced lung elasticity. Irreversible and progressive.
Chronic bronchitis - obstructed airflow due to increased mucous production/secretion and inflamed bronchioles due to exposure to irritants.
Emphysema - permanent enlargement of the airways and damaged alveolar walls due to toxins inhaled, reduced area for gas exchange.
COPD signs/symptoms
Productive cough, SOB, increased WOB, sputum increase
COPD drugs used
Oxygen therapy, salbutamol, ipratropium bromide, dexamethasone
COPD treatment
Salbutamol 10mg + Ipratropium bromide 500mcg nebulised
Dexamethasone 8mg IV/oral
Oxygen therapy, nasal prongs
asthma tx paed mild/moderate
Salbutamol pMDI + spacer, 4 breaths each dose, repeat at 20 minutes
6+ = 4-12 doses
1-5 = 2-6 doses
asthma tx paed severe
Salbutamol nebulised, repeat at 20min intervals
2-4 = 2.5mg (1.25mL)
5-11 = 2.5-5mg (1.25-2.5mL)
Ipratropium bromide 250mcg (1mL) nebulised
asthma tx paed critical
Salbutamol nebulised 10mg (5mL)
Ipratropium bromide nebulised 250mcg (1mL)
Adrenaline 10mcg/kg IM, repeat at 5-10mins, max 3 doses
Dexamethasone 600mcg/kg oral (max 12mg)
APO patho
When the left ventricular muscle weakens or fails, there’s a reduction in cardiac output. Causes back flow into the pulmonary arteries and capillaries. Due to the pressure difference, fluid moves into the pulmonary interstitial space and the alveolar.
APO signs/symptoms
Crackles, pink sputum, SOB, feelings of drowning, chest pain
APO drugs used
GTN, CPAP, furosemide
APO treatment
GTN 50mg patch, GTN 600mcg every 5 minutes (300mcg if elderly/frail)
CPAP
ACS patho
When an artery is blocked causing the heart muscle to become ishcaemic and weaken/breakdown.
Unstable angina vs normal angina
Unstable is constant with no relief, lasts longer than 10 minutes
STEMI vs NSTEMI/UA
STEMI is when there is complete occlusion, NSTEMI is when there is partial occlusion
ACS drugs used
GTN, aspirin, anti-nausea
ACS treatment (normal)
Aspirin 300mg
GTN 50mg patch
GTN 600mcg every 5 minutes (300mcg for elderly and frail)