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PHARM 1 Self > DRUG1USE > Flashcards

DRUG1USE Flashcards

1
Q

-Cimetidine (OAT)

A

Increase circulating drug level

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2
Q

-Proadifen (OCT)

A

Increase circulating drug level

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3
Q

-Probenecid

A

Increase circulating drug level

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4
Q
  • Ethanol
A

Decrease circulating drug level

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5
Q
  • Phenobarbital
A

Decrease circulating drug level

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6
Q

Bethanechol

A

Stimulate smooth muscle post-operatively – increased GI motility, sphincters relax, stimulate secretions

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7
Q

Carbachol

A

Wide-angle glaucoma (constrict ciliary muscle)

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8
Q

Methacholine

A

Slow heart in severe tachycardia

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9
Q

Pilocarpine

A

Glaucoma (short term treatment of acute angle-closure), treat dry mouth

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10
Q

Ambenonium

A

Myasthenia gravis

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11
Q

Edrophonium

A

Myasthenia gravis, ileus, arrhythmias, reversal of neuromuscular blockade (short)

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12
Q

Neostigmine

A

Myasthenia gravis (reference therapeutic agent), ileus, reversal of neuromuscular blockade (long)

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13
Q

Physostigmine

A

Glaucoma – given for short term treatment of acute angle-closure

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14
Q

Pyridostigmine

A

Myasthenia gravis

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15
Q
  • Diisopropyl-fluorophosphate
A

None

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16
Q
  • Echothiopate
A

Echothiopate for glaucoma

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17
Q
  • Carbaryl
A

None

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18
Q
  • Malathion
A

Lice

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19
Q
  • Parathion
A

None

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20
Q
  • Tetraethyl-pyrophosphate
A

None

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21
Q
  • Sarin
A

none

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22
Q
  • Soman
A

none

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23
Q

Pralidoxime

A

Step 2 following OP intoxication

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24
Q

Atropine

A

OP and cholinergic agonist toxicity, elicit tachycardia following brady from MI, anti-parkinson, relieves urinary incontinence, mydriasis (7-10 days), anti-motion sickness

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25
Q

Homatropine

A

Mostly used for eye effects (topical agent) – mydriasis (1-3 days)

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26
Q

Scopolamine

A

Anti-motion sickness, amnesia (pre-anesthetic), mydriasis (3-7 days), induction of amnesia

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27
Q

Methscopolamine

A

Mostly GI diseases

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28
Q

Trihexyphenidyl

A

Decrease uncoordinated movement and excess salivation for parkinsons

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29
Q

Tropicamide

A

Mostly used as topical ocular treatment – mydriasis (6 hours)

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30
Q

Cyclopentolate

A

Mydriasis – 1 day

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31
Q

Ipratropium

A

Topical - minimizes mucociliary clearance issues (pts with airway problems – COPD)

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32
Q

Tiotropium

A

Topical - targets bronchodilation and minimizes mucociliary clearance issues

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33
Q
  • Darifenacin
A

Urinary urgency, bladder spasms

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34
Q
  • Solifenacin
A

Urinary urgency, bladder spasms

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35
Q
  • Tolterodine
A

Urinary urgency, bladder spasms

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36
Q

Mecamylamine

A

Improve absorption from GI tract (oral – 12 hours), adjunct therapy for hypertension and peripheral vascular disease

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37
Q

Trimethaphan

A

IV infusion use (lasts minutes), adjunct therapy for hypertension and peripheral vascular disease, short-acting IV to minimize blood loss in surgery

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38
Q

Succinylcholine

A

Muscle relaxation for surgery, tracheal intubation, control of ventilation, convulsions

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39
Q

Curare

A

Muscle relaxation for surgery, tracheal intubation, control of ventilation, convulsions

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40
Q

Atracurium

A

Muscle relaxation for surgery, tracheal intubation, control of ventilation, convulsions

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41
Q

Cisatracurium

A

Muscle relaxation for surgery, tracheal intubation, control of ventilation, convulsions

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42
Q

Mivacurium

A

Muscle relaxation for surgery, tracheal intubation, control of ventilation, convulsions

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43
Q

Pancuronium

A

Muscle relaxation for surgery, tracheal intubation, control of ventilation, convulsions

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44
Q

Vecuronium

A

Muscle relaxation for surgery, tracheal intubation, control of ventilation, convulsions

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45
Q

Metaraminol

A

Vasopressor (hypotension – not shock)

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46
Q

Methoxamine

A

hypertension?

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47
Q

Phenylephrine

A

Nasal decongestant, vasopressor, mydriatic, overcome hypotension, local vasoconstrictor

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48
Q
  • a-methyldopa
A

Can be used for hypertension

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49
Q
  • Clonidine
A

Can be used for hypertension

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50
Q
  • Guanabenz
A

Can be used for hypertension

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51
Q

Amphetamine

A

Vasopressor

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52
Q

Ephedrine

A

Vasopressor, mydriatic, nasal decongestant, CNS stimulant, chronic orthostatic hypotension, stress incontinence

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53
Q

Dipivefrin

A

Open angle glaucoma

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54
Q

Epinephrine

A

Anaphylactic shock, severe allergic reactions, open glaucoma, slow profuse bleeding, increase systolic BP (B1/A1 effects), heart block/cardiac arrest

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55
Q

Norepinephrine

A

Vasopressor (shock) (IV only)

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56
Q

Dobutamine

A

Congestive heart failure, cardiogenic shock following MI

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57
Q

Isoproterenol

A

AV block, asthma – increase in cardiac output and decreased MAP with vasodilation

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58
Q

Albuterol

A

Bronchial asthma

59
Q

Metaproterenol

A

Vasopressor (hypotension – not shock), bronchial asthma

60
Q

Terbutaline

A

Asthma, relax pregnant uterus

61
Q

Bromocriptine

A

Anti-parkinson agent with CNS effects

62
Q

Dopamine

A

Vasopressor, very effective for shock, cardiogenic shock following MI

63
Q

Doxazosin

A

Urinary obstruction

64
Q

Prazosin

A

Hypertension – oral – 12 hours – urinary obstruction

65
Q
  • Tamsulosin
A

Urinary obstruction

66
Q
  • Terazosin
A

Urinary obstruction

67
Q

Phenoxy-benzamine

A

Lasts about 24 hours – oral or IV – pheochromocytoma (management of hypertension post-op)

68
Q

Phentolamine

A

Pheochromocytoma – preoperative management of hypertension/ inoperative or metastatic tumors

69
Q

Labetalol

A

Anti-hypertensive

70
Q

Atenolol

A

Effective anti-hypertensive w/o constriction of bronchial smooth muscle (asthma)

71
Q

Betaxolol

A

Effective anti-hypertensive w/o constriction of bronchial smooth muscle (asthma), open glaucoma

72
Q

Metoprolol

A

Effective anti-hypertensive w/o constriction of bronchial smooth muscle (asthma)

73
Q

Nadolol

A

Antihypertensive

74
Q
  • Carteolol
A

Open angle glaucoma

75
Q
  • Levobunolol
A

Open angle glaucoma

76
Q
  • Metipranolol
A

Open angle glaucoma

77
Q

Pindolol

A

Antihypertensive

78
Q

Propranolol

A

Antihypertensive, anti-arrhythmic, angina pectoris, migraines, prophylactics to prevent MI

79
Q

Timolol

A

Prophylactics to prevent MI, antihypertensive, angina pectoris, decrease IOP (glaucoma)

80
Q

a-methyldopa

A

Antihypertensive agent

81
Q

Guanethidine

A

Orally effective hypertensive agent

82
Q

Reserpine

A

Very potent, orally effective, long duration

83
Q
  • Cocaine
A

Hemostasis during surgery

84
Q
  • DMI (desmethyl-imipramine)
A

Hemostasis during surgery

85
Q

Tyramine

A

Vasopressor (shock or hypotension)

86
Q

Pseudoephedrine

A

Nasal congestion

87
Q
  • Acetazolamide
A

Decrease aqueous humor production – open angle glaucoma

88
Q

-Dichlorphenamide

A

Decrease aqueous humor production – open angle glaucoma

89
Q
  • Dorzolamide
A

Decrease aqueous humor production – open angle glaucoma

90
Q

Botulinum Toxin A

A

Blepharospasm (eyelid problem) and squinting (extraocular muscles)

91
Q

Azathioprine

A

Renal and other tissue transplantation, auto-immune disease

92
Q

Cyclophosphamide

A

Auto-immune diseases and bone marrow transplant

93
Q

Leflunomide

A

Rheumatoid arthritis (drug of choice), some auto-immune

94
Q

Methotrexate

A

Rheumatoid arthritis (drug of choice), some auto-immune

95
Q

Mycophenolate mofetil

A

Solid organ transplant, some auto-immune disease

96
Q

Prednisone

A

First-line for solid organ and hematopoietic stem cell transplant, management of various immune-disorders

97
Q

Sirolimus

A

Preserve solid organ transplants, steroid-resistant graft-versus-host disease in hematopoietic stem cell transplants

98
Q

Cyclosporine

A

Kidney, liver, and cardiac transplants – autoimmune disorders and inflammatory diseases (often combined with another drug)

99
Q

Tacrolimus (FK506)

A

Kidney, liver, and cardiac transplants – autoimmune disorders and inflammatory diseases (often combined with another drug)

100
Q

Anti-T cell globulin

A

Prolonged T cell depletion (more than 1 year) – late rejection as lymphoid system recovers

101
Q

Alemtuzumab

A

Produces prolonged depletion of T cell and other cells of immune system (1 year)

102
Q

Basiliximab

A

Depletes only antigen-activated T cells so reduced incidence of infection and malignancy

103
Q

Rh (D) immune globulin

A

Rh hemolytic disease

104
Q

Belatacept

A

Kidney transplantation to prevent rejection

105
Q

Interleukin-2

A

Metastatic melanoma and renal cell carcinoma

106
Q

IFN-y

A

Increase inflammatory response

107
Q

BCG

A

Cancer therapies

108
Q

Cetirizine

A

Allergic rhinitis

109
Q

Cyclizine

A

Motion sickness

110
Q

Dimenhydrinate

A

Allergic rhinitis, motion sickness

111
Q

Diphenhydramine

A

Motion sickness, allergic rhinitis

112
Q

Fexofenadine

A

Allergic rhinitis

113
Q

Loratadine

A

Allergic rhinitis

114
Q

Promethazine

A

Motion sickness

115
Q

Adalimumab

A

Parenteral only – rheumatoid arthritis and Crohn’s disease

116
Q

Etanercept

A

Parenteral only – rheumatoid arthritis and Crohn’s disease

117
Q

Infliximab

A

Parenteral only – rheumatoid arthritis and Crohn’s disease

118
Q

Anakinra

A

Rheumatoid arthritis (short ½ life, daily injection)

119
Q

Tofacitnib

A

Rheumatoid arthritis (oral – 5mg bid)

120
Q

Aspirin

A

OTC analgesic, antipyretic, cardiovascular prophylaxis, anti-inflammatory

121
Q

Diclofenac

A

Rx arthritis/anti-inflammatory

122
Q

Diclofenac w/ misoprostol

A

Rx arthritis/anti-inflammatory

123
Q

Ibuprofen

A

OTC analgesic, antipyretic, anti-inflammatory

124
Q

Indomethacin

A

Rx arthritis/anti-inflammatory

125
Q

Ketorolac

A

Post-surgical analgesic

126
Q

Naproxen

A

OTC analgesic, antipyretic, Rx anti-inflammatory

127
Q

Acetaminophen

A

Analgesic and antipyretic effects (not anti-inflamm)

128
Q

Celecoxib

A

Anti-inflammatory, antipyretic, analgesic – osteoarthritis and rheumatoid

129
Q

Rofecoxib

A

Anti-inflammatory, antipyretic, analgesic – osteoarthritis and rheumatoid

130
Q

Albuterol

A

Inhaled form – short term relief of asthma

131
Q

Salmeterol w/ fluticasone

A

Inhaled form but longer acting relief of asthma

132
Q

-Beclomethasone

A

Aerosol inhalation for asthma

133
Q
  • Budesonide
A

Aerosol inhalation for asthma

134
Q
  • Fluticasone
A

Aerosol inhalation for asthma

135
Q
  • Triamclinolone
A

Aerosol inhalation for asthma

136
Q

Prednisone

A

Oral – intermediate term relief, reduction in inflammation and hyper-responsiveness to control asthma

137
Q
  • Montelukast
A

Oral administration – can reduce corticosteroid dosage for asthma

138
Q
  • Zafirlukast
A

Oral administration – can reduce corticosteroid dosage for asthma

139
Q

Zileuton

A

Oral administration – asthma

140
Q
  • Cromolyn
A

Inhaled aerosol – effective prophylactically for asthma

141
Q
  • Nedocromil
A

Inhaled aerosol – effective prophylactically for asthma

142
Q

Ipratropium

A

Inhalation – useful for asthma patients intolerant of B2 agonists

143
Q

Theophylline

A

Long-term maintenance – oral therapy of asthma

PHARM 1 Self (6 decks)

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