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PHARM 1 Self > CLASS1Drugs > Flashcards

CLASS1Drugs Flashcards

1
Q

-Cimetidine (OAT)

A

Drug metabolism inhibitor

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2
Q

-Proadifen (OCT)

A

Drug metabolism inhibitor

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3
Q

-Probenecid

A

Drug metabolism inhibitor

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4
Q
  • Ethanol
A

Drug metabolism activators

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5
Q
  • Phenobarbital
A

Drug metabolism activators

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6
Q

Bethanechol

A

Cholinergic agonist – synthetic choline ester

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7
Q

Carbachol

A

Cholinergic agonist – synthetic choline ester

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8
Q

Methacholine

A

Cholinergic agonist – synthetic choline ester

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9
Q

Pilocarpine

A

Cholinergic agonist – natural alkaloid

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10
Q

Ambenonium

A

Competitive cholinesterase inhibitor - carbamate

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11
Q

Edrophonium

A

Competitive cholinesterase inhibitor - simple alcohol with quartenary ammonium

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12
Q

Neostigmine

A

Competitive cholinesterase inhibitor – carbamate with quartenary ammonium

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13
Q

Physostigmine

A

Competitive cholinesterase inhibitor – carbamate with tertiary amine

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14
Q

Pyridostigmine

A

Competitive cholinesterase inhibitor - carbamate

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15
Q
  • Diisopropyl-fluorophosphate
A

Noncompetitive cholinesterase inhibitor – OP insecticie

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16
Q
  • Echothiopate
A

Noncompetitive cholinesterase inhibitor – OP insecticie

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17
Q
  • Carbaryl
A

Noncompetitive cholinesterase inhibitor – OP insecticie

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18
Q
  • Malathion
A

Noncompetitive cholinesterase inhibitor – OP insecticie

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19
Q
  • Parathion
A

Noncompetitive cholinesterase inhibitor – OP insecticie

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20
Q
  • Tetraethyl-pyrophosphate
A

Noncompetitive cholinesterase inhibitor – OP insecticie

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21
Q
  • Sarin
A

Noncompetitive cholinesterase inhibitor – nerve gas

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22
Q
  • Soman
A

Noncompetitive cholinesterase inhibitor – nerve gas

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23
Q

Pralidoxime

A

AchE reactivator – cholinesterase inhibitor

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24
Q

Atropine

A

Cholinergic antagonist – highly muscarinic selective (low potency at nicotinic), no M subtype selectivity – 3 amine

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25
Q

Homatropine

A

Cholinergic antagonist – muscarinic selective – 3 amine

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26
Q

Scopolamine

A

Cholinergic antagonist – very muscarinic selective – 3 amine

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27
Q

Methscopolamine

A

Cholinergic antagonist – muscarinic selective – 4 ammonium

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28
Q

Trihexyphenidyl

A

Cholinergic antagonist – muscarinic selective – 3 amine

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29
Q

Tropicamide

A

Cholinergic antagonist – muscarinic selective – 3 amine

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30
Q

Cyclopentolate

A

Cholinergic antagonist – muscarinic selective

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31
Q

Ipratropium

A

Cholinergic antagonist – muscarinic selective – 4 ammonium

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32
Q

Tiotropium

A

Cholinergic antagonist – muscarinic selective

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33
Q
  • Darifenacin
A

Cholinergic antagonist – M3 selective

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34
Q
  • Solifenacin
A

Cholinergic antagonist – M3 selective

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35
Q
  • Tolterodine
A

Cholinergic antagonist – M3 selective

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36
Q

Mecamylamine

A

Cholinergic antagonist – nicotinic selective – 2 amine – nondepolarizing competitive antagonists

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37
Q

Trimethaphan

A

Cholinergic antagonist – nicotinic selective – sulfonium- nondepolarizing competitive antagonists

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38
Q

Succinylcholine

A

Cholinergic antagonist – depolarizing, noncompetitive receptor agonist for ACh action

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39
Q

Curare

A

Cholinergic antagonist – non-depolarizing – long acting, benzylisoquinoline

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40
Q

Atracurium

A

Cholinergic antagonist – non-depolarizing

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41
Q

Cisatracurium

A

Cholinergic antagonist – non-depolarizing – intermediate length, benzylisoquinoline

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42
Q

Mivacurium

A

Cholinergic antagonist – non-depolarizing – short acting, benzylisoquinoline

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43
Q

Pancuronium

A

Cholinergic antagonist – non-depolarizing – long acting, ammonio steroid

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44
Q

Vecuronium

A

Cholinergic antagonist – non-depolarizing – intermediate length, ammonio steroid

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45
Q

Metaraminol

A

Adrenergic agonist – a1 selective (a1&raquo_space; a2)

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46
Q

Methoxamine

A

Adrenergic agonist – a1 selective

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47
Q

Phenylephrine

A

Adrenergic agonist – a1 selective (a1 = a2)

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48
Q
  • a-methyldopa
A

Adrenergic agonist – a2 selective

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49
Q
  • Clonidine
A

Adrenergic agonist – a2 selective

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50
Q
  • Guanabenz
A

Adrenergic agonist – a2 selective

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51
Q

Amphetamine

A

Adrenergic agonist – mixed a/b,

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52
Q

Ephedrine

A

Adrenergic agonist – mixed a/b, NE releasing agent

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53
Q

Dipivefrin

A

Adrenrgic agonist – mixed a/b NE releasing agent

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54
Q

Epinephrine

A

Adrenergic agonist – mixed a/b – a1 = a2, B1 = B2

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55
Q

Norepinephrine

A

Adrenergic agonist – mixed a/b – a1 = a2, B1»B2

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56
Q

Dobutamine

A

Adrenergic agonist – B1 selective

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57
Q

Isoproterenol

A

Adrenergic agonist – B non-selective

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58
Q

Albuterol

A

Adrenergic agonist – B2 selective

59
Q

Metaproterenol

A

Adrenergic agonist – B2 selective

60
Q

Terbutaline

A

Adrenergic agonist – B2 selective

61
Q

Bromocriptine

A

Adrenergic agonist – dopamine (D2)

62
Q

Dopamine

A

Adrenergic agonist – dopamine, D1 = D2

63
Q

Doxazosin

A

Adrenergic antagonist – a1 selective&raquo_space;» a2

64
Q

Prazosin

A

Adrenergic antagonist – a1 selective&raquo_space;» a2

65
Q
  • Tamsulosin
A

Adrenergic antagonist – a1 selective&raquo_space;» a2

66
Q
  • Terazosin
A

Adrenergic antagonist – a1 selective&raquo_space;» a2

67
Q

Phenoxy-benzamine

A

Adrenergic antagonist – a non-selective a1 > a2

68
Q

Phentolamine

A

Adrenergic antagonist – a non-selective a1 = a2

69
Q

Labetalol

A

Adrenergic antagonist – mixed a/b – B1 = B2 > a1 > a2

70
Q

Atenolol

A

Adrenergic antagonist – B1 selective&raquo_space;» B2

71
Q

Betaxolol

A

Adrenergic antagonist – B1 selective&raquo_space;» B2

72
Q

Metoprolol

A

Adrenergic antagonist – B1 selective&raquo_space;» B2

73
Q

Nadolol

A

Adrenergic antagonist – B nonselective B1 = B2

74
Q
  • Carteolol
A

Adrenergic antagonist – B nonselective

75
Q
  • Levobunolol
A

Adrenergic antagonist – B nonselective

76
Q
  • Metipranolol
A

Adrenergic antagonist – B nonselective

77
Q

Pindolol

A

Adrenergic antagonist – B nonselective B1 = B2

78
Q

Propranolol

A

Adrenergic antagonist – B nonselective B1 = B2

79
Q

Timolol

A

Adrenergic antagonist – B nonselective B1 = B2

80
Q

a-methyldopa

A

False transmitter

81
Q

Guanethidine

A

Synaptic vesicle depletion and membrane depolarization

82
Q

Reserpine

A

Synaptic vesicle depletion (pre-junctional)

83
Q
  • Cocaine
A

Amine I transport inhibitor

84
Q
  • DMI (desmethyl-imipramine)
A

Amine I transport inhibitor

85
Q

Tyramine

A

NE releasing agent

86
Q

Pseudoephedrine

A

NE releasing agent

87
Q
  • Acetazolamide
A

Carbonic anhydrase inhibitor

88
Q

-Dichlorphenamide

A

Carbonic anhydrase inhibitor

89
Q
  • Dorzolamide
A

Carbonic anhydrase inhibitor

90
Q

Botulinum Toxin A

A

Misc. ophthalmology

91
Q

Azathioprine

A

General growth inhibitor

92
Q

Cyclophosphamide

A

General growth inhibitor

93
Q

Leflunomide

A

General growth inhibitor

94
Q

Methotrexate

A

General growth inhibitor

95
Q

Mycophenolate mofetil

A

General growth inhibitor

96
Q

Prednisone

A

Glucocorticoid

97
Q

Sirolimus

A

mTOR inhibitor

98
Q

Cyclosporine

A

Calcineurin inhibitor

99
Q

Tacrolimus (FK506)

A

Calcineurin inhibitor

100
Q

Anti-T cell globulin

A

Antibodies and fusion proteins

101
Q

Alemtuzumab

A

Antibodies and fusion proteins

102
Q

Basiliximab

A

Antibodies and fusion proteins

103
Q

Rh (D) immune globulin

A

Antibodies and fusion proteins

104
Q

Belatacept

A

Antibodies and fusion proteins

105
Q

Interleukin-2

A

Cyokine

106
Q

IFN-y

A

Cytokine

107
Q

BCG

A

Adjuvant

108
Q

Cetirizine

A

H1 antihist – 2nd generation

109
Q

Cyclizine

A

H1 antihist – 1st generation

110
Q

Dimenhydrinate

A

H1 antihist – 1st generation

111
Q

Diphenhydramine

A

H1 antihist – 1st generation

112
Q

Fexofenadine

A

H1 antihist – 2nd generation

113
Q

Loratadine

A

H1 antihist– 2nd generation

114
Q

Promethazine

A

H1 antihist – 1st generation

115
Q

Adalimumab

A

Anti-TNFa agents

116
Q

Etanercept

A

Anti-TNFa agents

117
Q

Infliximab

A

Anti-TNFa agents

118
Q

Anakinra

A

Anti-IL1 agents

119
Q

Tofacitnib

A

Jak kinase inhibitors

120
Q

Aspirin

A

Nonselective COX inhibitors

121
Q

Diclofenac

A

Nonselective COX inhibitors

122
Q

Diclofenac w/ misoprostol

A

Nonselective COX inhibitors

123
Q

Ibuprofen

A

Nonselective COX inhibitors

124
Q

Indomethacin

A

Nonselective COX inhibitors

125
Q

Ketorolac

A

Nonselective COX inhibitors

126
Q

Naproxen

A

Nonselective COX inhibitors

127
Q

Acetaminophen

A

Nonselective COX inhibitors

128
Q

Celecoxib

A

COX-2 selective inhibitors

129
Q

Rofecoxib

A

COX-2 selective inhibitors

130
Q

Albuterol

A

B2 adrenergic agonist

131
Q

Salmeterol w/ fluticasone

A

B2 adrenergic agonist

132
Q

-Beclomethasone

A

Corticosteroid

133
Q
  • Budesonide
A

Corticosteroid

134
Q
  • Fluticasone
A

Corticosteroid

135
Q
  • Triamclinolone
A

Corticosteroid

136
Q

Prednisone

A

Corticosteroid

137
Q
  • Montelukast
A

Leukotriene modulator

138
Q
  • Zafirlukast
A

Leukotriene modulator

139
Q

Zileuton

A

Leukotriene modulator

140
Q
  • Cromolyn
A

Degranulation inhibitor

141
Q
  • Nedocromil
A

Degranulation inhibitor

142
Q

Ipratropium

A

Muscarinic cholinergic antagonist

143
Q

Theophylline

A

Miscellaneous asthma

PHARM 1 Self (6 decks)

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