Drug toxicity and Antidotes Flashcards by Louis Andres | Brainscape

Q

Acetaminophen

A

N-acetylcysteine (replenishes glutathione)

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Q

Acetylcholinesterase inhibitors, organophosphates

A

Atropine + pralidoxime

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Q

Amphetamines (basic)

A

Ammonium chloride (NH4Cl, acidify urine)

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Q

Antimuscarinic, anticholinergic agents

A

Physostigmine salicylate,Control hyperthermia

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Q

Benzodiazepines

A

Flumazenil

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Q

B-Blockers

A

Glucagon

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Q

Carbon monoxide

A

100% O2, hyperbaric O2

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Q

Copper, arsenic, gold

A

Penicillamine

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Q

Cyanide

A

Nitrite + Thiosulfate, hydroxocobalamine

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Q

Digitalis

A

Anti-dig Fab fragments

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Q

Heparin

A

Protamine sulfate

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Q

Iron

A

Deferoxamine, deferasirox

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Q

Lead

A

EDTA, dimercaprol, succimer, penicillamine

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Q

Mercury, arsenic, gold

A

Dimercaprol (BAL), succimer

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Q

Methanol, ethylene glycol (antifreeze)

A

Fomepizole > ethanol, dialysis

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Q

Methemoglobin

A

Methylene blue, vitamin C

Q

Opioids

A

Naloxone

Q

Salicylates

A

Sodium bicarbonate (NaHCO3, alkalanize urine), dialysis

Q

Tricyclic antidepressants

A

Sodium bicarbonate (NaHCO3, plasma alkalinization)

Q

tPA, streptokinase, urokinase

A

Aminocaproic acid

Q

Warfarin

A

Vitamin K, plasma (if active bleeding)