Common Teratogens (c/o Topnotch) Flashcards
1
Q
ACE inhibitors
A
Fetal renal damage
2
Q
Antiepileptic drugs (Carbamazepine)
A
Neural tube defects
3
Q
Phenytoin
A
Fetal hydantoin syndrome
4
Q
Oral hypoglycemic agents
A
Neonatal hypoglycemia
5
Q
Diethystilbestrol (DES)
A
Vaginal clear cell adenoCA
6
Q
Ethanol
A
Fetal alcoholic syndrome
7
Q
Lithium
A
Ebstein’s anomaly
8
Q
Isotretinoin
A
Craniofacial malformation
9
Q
Iodide
A
Congenital hypothyroidism
10
Q
Misoprostol
A
Moebius sequence
11
Q
Penicillamine
A
Cutis laxa
12
Q
Thalidomide
A
Phocomelia
13
Q
Smoking
A
IUGR
14
Q
Tetracycline
A
Teeth discoloration
15
Q
Streptomycin
A
Ototoxicity
16
Q
Methimazole
A
Aplasia cutis congenita
17
Q
Sulfonamides
A
Kernicterus
18
Q
Fluoroquinolone
A
Cartilage damage
19
Q
Warfarin
1st Trimester
2nd Trimester
3rd Trimester
A
1st Trimester - Chondrodysplasia
2nd Trimester - CNS malformations
3rd Trimester - Bleeding diatheses
