drug specific info Flashcards
nicotine ROA
smoking (cigarettes), mucous membrane (pipe tobacco, cigars etc)
nicotine action in brain
acts on receptors, agonist of acetlycholine
, stimulates CNS
nicotine psychoactive effects
arousal, enhanced mood, increased attention
nicotine half life/ metabolism
2-3 hrs
nicotine tolerance
quickly for nausea vomiting and dysphoria
nicotine withdrawal
restlessness, irritability, drowsiness, weight gain (intense 24-48 hrs but diminishes over few weeks
alcohol ROA
mouth, stomach, intestines
alcohol action in brain
acts on cell membrane, CNS depressant
alcohol psychoative effects
depends on prior psych state and situ of alcohol consumption
alcohol half life
NA, depends on weight, height, indiv diff etc, food and beverage intake
alcohol tolerance
amount of liver enzyme increases
alcohol withdrawal
nausea, vomiting, tremors, lasts several days
opioids ROA
intravenous injection, smoking and vapour
opioids action in brain
binds to opioid receptors and promotes release of dopamine
opioids psychoative effects
euphoria
opioids half life
3-6 hrs
opioids tolerance
euphoria quickly but others slow e.g constipation and pin point pupils
opioids withdrawal
at height after 2 days, then wears off, very unpleasant but not life threatening e.g sweating, vomiting and chills
cocaine ROA
injection, intranasal, smoking, vapour
cocaine action in brain
facilitates release of monoamines and blocks reuptake
cocaine psychoative effects
arousal, reduced fatigue, pos mood
cocaine half life
1 hr
amphetamine = 12-13 hrs
cocaine tolerance
fever, monoamine transporters and receptors
cocaine withdrawal
within 24 hrs of last dose, lasts 3-4 weeks, depression, disturbed sleep, anxiety
