Drug Side Effects (DIT Pharm 11)

Question 1

Flushing

Answer 1

Vancomycin
Niacin
Adenosine
Dihydropyridine Ca channel blockers

Question 2

Coronary vasospasm

Answer 2

cocaine
amphetamines
triptans
ergotamine

Question 3

Dilated cardiomyopathy

Answer 3

Doxorubicin

Daunorubicin

Question 4

Torsades de Pointes

Answer 4

Potassium Channel blockers
Sodium channel blockers
Macrolides
Haloperidol
Chloroquine
Protease inhibitors

Question 5

Thrombocytopenia

Answer 5

Heparin

Cimetidine

Question 6

Agranulocytosis

Answer 6

3 C’s: clozapine, carbamazepine, colchicine
Anti-thyroid: propyltiouracil, methimazole
and dapsone

Question 7

Aplastic Anemia

Answer 7

chloramphenicol
benzene
NSAIDs
PTU
methimazole

Question 8

Gray Baby syndrome

Answer 8

chlorampenicol

Question 9

Hemolysis in G6PD deficiency

Answer 9

Isoniazid
sulfonamides
primaquine
ASA (high dose) 
Ibuprofen
nitrofurantoin
dapsone
fava beans
naphthalene

Question 10

Thrombosis

Answer 10

oral contraceptives

Question 11

Pulmonary fibrosis

Answer 11

bleomycin
busulfan
amiodarone

Question 12

cough

Answer 12

ACE inhibitors

Question 13

pseudomembranous colitis

Answer 13

clindamycin

amoxicillin/ampicillin

Question 14

Hepatic necrosis

Answer 14

halothane
APAP
valproic acid
amanita phalloides

Question 15

Hepatitis

Answer 15

isoniazid

Question 16

tertiary adrenal insufficiency

Answer 16

corticosteroid withdrawal

Question 17

Gynecomastia

Answer 17

STACKED:
spironolactone
THC (marijuana)
Alcohol (chronic)
Cimetidine
Ketoconazole
Estrogens
Digoxin

Question 18

Hot flashes

Answer 18

tamoxifen and clomiphene (SERMs)

Question 19

Hypothyroidism

Answer 19

Amiodarone
lithium
sulfonamides

Question 20

Gout

Answer 20

diuretics (loop and thiazides)
niacin
cyclosporine
pyrazinamide

Question 21

Gingival hyperplasia

Answer 21

phenytoin

verapamil

Question 22

Osteoporosis

Answer 22

Corticosteroids

heparin

Question 23

Photosensitivity

Answer 23

SAT for photo
Sulfonamides
Amiodarone
Tetracyclines

Question 24

Stevens-Johnson Syndrome

Answer 24

Steve Jobs made APPLE PCS
Allopurinol
Phenytoin
Penicillin
Lamotrigine
Ethosuximide

Phenobarbital
Carbamazepine
Sulfa drugs

Question 25

Drug Induced Lupus

Answer 25

SHIPP
Sulfonamides
Hydralazine
Isoniazid
Phenytoin
Procainamide

Question 26

Tendinitis/Cartilage damage

Answer 26

fluoroquinolones

Question 27

Interstitial nephritis

Answer 27

NSAIDs
furosemide
Antibx

Question 28

Diabetes insipidis

Answer 28

lithium

demeclocycline

Question 29

Fanconi Syndrome

Answer 29

expired tetracycline

heavy metals and Wilson dz also

Question 30

Hemorrhagic cystitis

Answer 30

cyclophosphamide

ifosfamide

Question 31

Parkinson-like syndrome

Answer 31

Metaclopramide
Antipsychotics
reserpine

Question 32

Cinchonism- dizziness, headaches, vision changes, tinnitus

Answer 32

quinidine and quinine

Question 33

Seizures

Answer 33

Buproprion
imipenem/cilastatin
isoniazid
tramadol
metoclopramide
Benzodiazepine/alcohol withdrawal

Question 34

Tardive dyskinesia

Answer 34

antipsychotics

metoclopramide

Question 35

Disulfiram-like reaction

Answer 35

Metronidazole
certain cephalosporins
procarbazine
First-generation sulfonylureas
disulfiram

Question 36

nephrotoxicity and neurotoxicity

Answer 36

aminoglycosides
cisplatin
polymixins

Question 37

nephrotoxicity and ototoxicity

Answer 37

aminoglycosides
vancomycin
loop diuretics
cisplatin

Question 38

anticholinergic effects

Answer 38

atropine
TCAs
H1 blockers
low-potency neuroleptics

Question 39

Bonus: which drug needs follow-up checks of PFTs, LFTs, and TFTs?

Answer 39

amiodarone