Drug Side Effects (DIT Pharm 11) Flashcards

1
Q

Flushing

A

Vancomycin
Niacin
Adenosine
Dihydropyridine Ca channel blockers

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2
Q

Coronary vasospasm

A

cocaine
amphetamines
triptans
ergotamine

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3
Q

Dilated cardiomyopathy

A

Doxorubicin

Daunorubicin

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4
Q

Torsades de Pointes

A
Potassium Channel blockers
Sodium channel blockers
Macrolides
Haloperidol
Chloroquine
Protease inhibitors
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5
Q

Thrombocytopenia

A

Heparin

Cimetidine

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6
Q

Agranulocytosis

A

3 C’s: clozapine, carbamazepine, colchicine
Anti-thyroid: propyltiouracil, methimazole
and dapsone

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7
Q

Aplastic Anemia

A
chloramphenicol
benzene
NSAIDs
PTU
methimazole
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8
Q

Gray Baby syndrome

A

chlorampenicol

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9
Q

Hemolysis in G6PD deficiency

A
Isoniazid
sulfonamides
primaquine
ASA (high dose) 
Ibuprofen
nitrofurantoin
dapsone
fava beans
naphthalene
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10
Q

Thrombosis

A

oral contraceptives

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11
Q

Pulmonary fibrosis

A

bleomycin
busulfan
amiodarone

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12
Q

cough

A

ACE inhibitors

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13
Q

pseudomembranous colitis

A

clindamycin

amoxicillin/ampicillin

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14
Q

Hepatic necrosis

A

halothane
APAP
valproic acid
amanita phalloides

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15
Q

Hepatitis

A

isoniazid

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16
Q

tertiary adrenal insufficiency

A

corticosteroid withdrawal

17
Q

Gynecomastia

A
STACKED:
spironolactone
THC (marijuana)
Alcohol (chronic)
Cimetidine
Ketoconazole
Estrogens
Digoxin
18
Q

Hot flashes

A

tamoxifen and clomiphene (SERMs)

19
Q

Hypothyroidism

A

Amiodarone
lithium
sulfonamides

20
Q

Gout

A

diuretics (loop and thiazides)
niacin
cyclosporine
pyrazinamide

21
Q

Gingival hyperplasia

A

phenytoin

verapamil

22
Q

Osteoporosis

A

Corticosteroids

heparin

23
Q

Photosensitivity

A

SAT for photo
Sulfonamides
Amiodarone
Tetracyclines

24
Q

Stevens-Johnson Syndrome

A
Steve Jobs made APPLE PCS
Allopurinol
Phenytoin
Penicillin
Lamotrigine
Ethosuximide

Phenobarbital
Carbamazepine
Sulfa drugs

25
Q

Drug Induced Lupus

A
SHIPP
Sulfonamides
Hydralazine
Isoniazid
Phenytoin
Procainamide
26
Q

Tendinitis/Cartilage damage

A

fluoroquinolones

27
Q

Interstitial nephritis

A

NSAIDs
furosemide
Antibx

28
Q

Diabetes insipidis

A

lithium

demeclocycline

29
Q

Fanconi Syndrome

A

expired tetracycline

heavy metals and Wilson dz also

30
Q

Hemorrhagic cystitis

A

cyclophosphamide

ifosfamide

31
Q

Parkinson-like syndrome

A

Metaclopramide
Antipsychotics
reserpine

32
Q

Cinchonism- dizziness, headaches, vision changes, tinnitus

A

quinidine and quinine

33
Q

Seizures

A
Buproprion
imipenem/cilastatin
isoniazid
tramadol
metoclopramide
Benzodiazepine/alcohol withdrawal
34
Q

Tardive dyskinesia

A

antipsychotics

metoclopramide

35
Q

Disulfiram-like reaction

A
Metronidazole
certain cephalosporins
procarbazine
First-generation sulfonylureas
disulfiram
36
Q

nephrotoxicity and neurotoxicity

A

aminoglycosides
cisplatin
polymixins

37
Q

nephrotoxicity and ototoxicity

A

aminoglycosides
vancomycin
loop diuretics
cisplatin

38
Q

anticholinergic effects

A

atropine
TCAs
H1 blockers
low-potency neuroleptics

39
Q

Bonus: which drug needs follow-up checks of PFTs, LFTs, and TFTs?

A

amiodarone