Drug Side Effects & CIs Flashcards

1
Q

NSAIDs (Aspirin, Diclofenac, Ibuprofen)

A

Gastritis
Bronchospasm
Hypersensitivity

CI:
Ulcer/bleeding
NSAID-induced asthma
Coagulopathy

Avoid in children

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2
Q

Paracetamol

A

Avoid in hepatic inpairment

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3
Q

Opiates (codeins, meptazinol, oxycodone, pethidine, tramadol, morphine)

A
Nausea & vomiting
Constipation
Drowsiness
Hypotension
Resp depression
Dependence

CI:
Acute resp depression
Acute alcoholism

Use with caution in head injury (affect neuro assessment)

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4
Q

Metoclopramide

A

Extrapyramidal SE

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5
Q

Antihistamines (chlorphenamine, cetirizine, levocetirizine, fenofexadine, loratadine)

A
Drowsiness
Urinary retention
Dry mouth
Blurred vision
GI disturbances
Arrhythmias
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6
Q

H2 blockers (cimetidine, ranitidine)

A

GI disturbance
Raised LFTs
May mask symptoms of gastric ca

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7
Q

PPIs (omeprazole, lansoprazole, pantoprazole)

A

GI disturbance
Hypersensitivity
May mask symptoms of gastric ca

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8
Q

Heparins

A
Bleeding
Thrombocytopenia
Hypersensitivity
Hyperkalaemia
Osteoporosis (prolonged use)
CI:
Coagulopathy
Peptic ulcer
Recurrent cerebral bleed
Recent trauma/surgery
Active bleeding
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9
Q

Temazepam

A

Drowsiness

Dependence

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10
Q

Zopiclone

A

Drowsiness
Dependence
Bitter taste
GI disturbances

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11
Q

Haloperidol

A
Extrapyramidal effects
Sedation
Hypotension
Anti-muscarinic effects
Meuroleptic malignant syndrome
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12
Q

Naloxone

A

Tachycardia

Fibrillation

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13
Q

Flumazenil

A

Convulsions
N&V
Flushing

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14
Q

Co-amoxiclav

A

May contribute to C.Diff infection

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15
Q

Gentamicin

A

Oto & nephro-toxicity

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