Drug Side Effects Flashcards
Levodopa
Dyskinesia
On-off effect
Palpitations
Postural hypotension
Drowsiness
Psychosis
Anorexia
Less effective with time
Rifampicin
Orange secretions
Thrombocytopenia
Nausea & vomiting
CYP inducer
Isoniazid
Peripheral neuropathy (give pyridoxine (B6))
Hepatitis
Agranulocytosis
CYP inhibitor
Pyrazinamide
Gout
Ethambutamol
Visual impairment
Methotrexate
Myelosuppression
Cirrhosis
Pneumonitis
Sulfasalazine
Rash
Oligospermia
Heinz body anaemia
Interstitial lung disease
Insomnia
Stomatitis
Tinnitus
Facial oedema
Seizure
Vasculitis
Vertigo
Leflunomide
Liver damage
Interstitial lung disease
Hypertension
Hydroxychloroquine
Retinopathy
Corneal deposits
Prednisolone
Cushing’s
Osteoporosis
Impaired glucose tolerance
Hypertension
Cataract
Metformin
GI upset
Lactic acidosis
Sulphonylureas
Hypoglycaemia
Increased appetite -> weight gain
SIADH
Cholestasis
Glitazones
Fluid retention
Weight gain
Liver dysfunction
Fractures
Gliptins
Pancreatitis
Retinoids
Teratogenicity - females should use 2 forms of contraception
Dry skin/eyes/lips/mouth - most common
Low mood
Raised triglycerides
Hair thinning
Nose bleeds
Intracranial hypertension (do not give with TCAs)
Photosensitivity