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AKT > Drug Side Effects > Flashcards

Drug Side Effects Flashcards

1
Q

Levodopa

A

Dyskinesia
On-off effect
Palpitations
Postural hypotension
Drowsiness
Psychosis
Anorexia
Less effective with time

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2
Q

Rifampicin

A

Orange secretions
Thrombocytopenia
Nausea & vomiting
CYP inducer

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3
Q

Isoniazid

A

Peripheral neuropathy (give pyridoxine (B6))
Hepatitis
Agranulocytosis
CYP inhibitor

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4
Q

Pyrazinamide

A

Gout

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5
Q

Ethambutamol

A

Visual impairment

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6
Q

Methotrexate

A

Myelosuppression
Cirrhosis
Pneumonitis

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7
Q

Sulfasalazine

A

Rash
Oligospermia
Heinz body anaemia
Interstitial lung disease
Insomnia
Stomatitis
Tinnitus
Facial oedema
Seizure
Vasculitis
Vertigo

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8
Q

Leflunomide

A

Liver damage
Interstitial lung disease
Hypertension

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9
Q

Hydroxychloroquine

A

Retinopathy
Corneal deposits

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10
Q

Prednisolone

A

Cushing’s
Osteoporosis
Impaired glucose tolerance
Hypertension
Cataract

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11
Q

Metformin

A

GI upset
Lactic acidosis

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12
Q

Sulphonylureas

A

Hypoglycaemia
Increased appetite -> weight gain
SIADH
Cholestasis

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13
Q

Glitazones

A

Fluid retention
Weight gain
Liver dysfunction
Fractures

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14
Q

Gliptins

A

Pancreatitis

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15
Q

Retinoids

A

Teratogenicity - females should use 2 forms of contraception
Dry skin/eyes/lips/mouth - most common
Low mood
Raised triglycerides
Hair thinning
Nose bleeds
Intracranial hypertension (do not give with TCAs)
Photosensitivity

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16
Q

Thiazide diuretics (common)

A

Common:
Hypochloraemic alkalosis
Nausea
Constipation
Diarrhoea
Dizziness
Gout
Hyponatraemia
Hypokalaemia
Hypercalcaemia
Headache
Urticaria

17
Q

Thiazide diuretics (uncommon)

A

Uncommon:
Agranulocytosis
Aplastic anaemia
Leukopenia
Pancreatitis
Photosensitivity
Thrombocytopenia

18
Q

Ciclosporin

A

Gingival hyperplasia
Eye inflammation
Hyperglycaemia
Hyperlipidaemia
Hypertension
Gout
Gynaecomastia
Haemolytic anaemia
Intracranial hypertension
Leukopenia
Pancreatitis

19
Q

Phenytoin

A

Agranulocytosis
C+N+V
Confusion
Gingival hyperplasia
Hair changes
Headache
Movement disorders
Polyarteritis nodosa
Severe cutaneous adverse reaction
SLE
Vertigo

20
Q

Amiodarone

A

Thyroid dysfunction
Corneal deposits
Photosensitivity
Pulmonary fibrosis/pneumonitis
Liver fibrosis/hepatitis
Slate grey appearance
Peripheral neuropathy
Constipation
Altered taste
Bradycardia
Thrombophlebitis

AKT (7 decks)

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