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CNS Drugs > Drug Replacement For Dopamine > Flashcards

Drug Replacement For Dopamine Flashcards

1
Q

Dopamine replacement and MOA

A

levadopa + carbidopa (best used both)
MOA: converts into dopamine and activates dopamine recepters
DOC

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2
Q

Dopamine agonist and MOA

A

Premipexole, rapinirole, bromocriptine
MOA activates DA receptors
Second DOC and if px develops tolerance to levadopa

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3
Q

COMT inhibitors and MOA

A

Entacapone tolcapone
MOA inhibits breakdown of levadopa
Best used with levadopa

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4
Q

Dopamine releasers and MOA

A

Amantadine
MOA promotes release of dopamine
Not DOA

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5
Q

MAO-B inhibitors and MOA

A

Selegiline rasagiline

MOA inhibits breakdown of dopamine

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CNS Drugs (3 decks)

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