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Pharm > Drug reactions > Flashcards

Drug reactions Flashcards

1
Q

Coronary vasospasm

A

cocaine, sumatriptan, ergot alkaloids

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2
Q

Cutaneous flushing

A

Vancomycin, Adenosine, Niacin, Ca channel blockers “VANC”

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3
Q

Dilated cardiomyopathy

A

Doxorubicin (adriamycin), daunorubicin

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4
Q

Torsades de pointes

A

Class III (sotalol) & class IA (quinidine) antiarrythmics

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5
Q

Agranulocytosis

A

Clozapine, Carbamazepine, Colchicine, Propylthiouracil, Methimazole, Dapsone

“Agranulocytosis Could Certainly Cause Pretty Major Damage”

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6
Q

Aplastic anemia

A

Chloramphenicol, benzene, NSAIDs, propylthiouracil, methimazole

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7
Q

Direct Coobs (+) hemolytic anemia

A

Methyldopa, penicillin

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8
Q

Gray baby syndrome

A

chloramphenicol

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9
Q

Hemolysis in GSPD deficient

A

Isoniazid, Sulfonamides, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin

“Hemolysis IS PAIN”

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10
Q

Megaloblastic anemia

A

Phenytoin, Methotrexate, Sulfa drugs

“PMS”

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11
Q

Thrombotic complications

A

OCPs (eg-estrogens)

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12
Q

Cough

A

ACEIs

ARBs -> no cough

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13
Q

Pulmonary fibrosis

A

Methotrexate, Cyclophosphamide, BLeomycin, Amiodarone, Busulfan
“an MC BlABs”

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14
Q

Acute cholestatic hepatitis, jaundice

A

Erythromycin

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15
Q

Focal to massive hepatic necrosis

A

Halothane, Amanita phalloides, Valproic acid, Acetaminophen

“liver HAVAc”

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16
Q

Hepatitis

A

INH = directly hepatotoxic

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17
Q

Pseudomembranous colitis

A

Clindmycin, ampicillin

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18
Q

Adrenocortical insufficiency

A

Glucocorticoid withdrawal (HPA suppression)

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19
Q

Gynecomastia

A

Spironolactone, Digitalis, Cimetidine, Alcohol (chronic), Ketoconazole

“Some Drugs Create Awkward Knockers”

20
Q

Hot flashes

A

tamoxifen, clomiphene

21
Q

Hyperglycemia

A

Niacin, tacrolimus, protease inhibitors, HCTZ, corticosteroids

22
Q

Hypothyroid

A

Lithium, amiodarone, sulfonamides

23
Q

Fat redistribution

A

glucocorticoids, protease inhibitors

24
Q

Gingival hyperplasia

A

Phenytoin, verapamil

25
Q

Gout

A

Furosemide, thiazides, niacin, cyclosporines

26
Q

Myopathies

A

Fibrates, Niacin, Colchicine, Hydroxychloroquine, IFN-a, Penicillamine, Statins, Glucocorticoids

“Fish N CHIPS Give you myopathies”

27
Q

Osteoporosis

A

Corticosteroids, heparin

28
Q

Photosensitivity

A

Sulfonamides, Amiodarone, Tetracycline

“SAT for a photo”

29
Q

Rash (Stevens-Johnson Syndrome)

A

Penicillin, Ethosuximide, Carbamazepine, Sulfa drugs, Lamotrigine, Allopurinol, Phenytoin, Phenobarbitol

“Rash after a PEC SLAPP”

30
Q

SLE-like syndrome

A

Hydralazine, INH, Procainamide, Phenytoin

“It’s not HIPP to have lupus”

31
Q

Teeth (kids)

A

Tetracyclines

32
Q

Tendonitis, tendon rupture, cartilage damage

A

Fluoroquinolones

33
Q

Diabetes insipidus

A

Lithium, demeclocycline

34
Q

Fanconi’s syndrome

A

expired tetracycline

35
Q

Hemorrhagic cystitis

A

Cyclophosphamide, ifosfamide (prevent with mesna)

36
Q

Interstitial nephritis

A

Methicillin, NSAIDs, furosemide

37
Q

SIADH

A

carbamazepine, cyclophosphamide

38
Q

Cinchonism

A

Quinidine, quinine

39
Q

Parkinson-like syndrome

A

Antipsychotics, reserpine, metoclopramide

40
Q

Seizure

A

Isoniazid, Bupropion, Imipenem/cilastatin, Tramadol, Enflurane, Metoclopromide

“with seizures, I BITE My tongue”

41
Q

Tardive dyskinesia

A

antipsychotics

42
Q

Antimuscarinic

A

Atropine, TCAs, H1-blockers, neuroleptics

43
Q

Disulfiram-like rxn

A

Metronidazole, some cephalosporins, procarbazine, 1st gen sulfonylureas

44
Q

Nephrotoxicity

A

Aminoglycosides, vancomycin, loop diuretics, cisplatin

45
Q

P450 Inducers

A 
Modafinil
Barbituates
St. John's wort
Phenytoin
Rifampin
Griseofulvin
Carbamazepine
Chronic Alcohol

“Momma Barb Steals Phen-phen and Refuses Greasy Carbs Chronically”

46
Q

P450 Inhibitors

A 
Macrolides
Amiodarone
Grapefruit juice
Isoniazid
Cimetidine
Ritonavir
Acute alcohol
Ciprofloxacin
Ketoconazole
Sulfonamides
Gemfibrozil
Quinidine

“MAGIC RACKS in GQ”

Pharm (14 decks)

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