Autonomics Flashcards
Sympathetic receptors
alpha & Beta
Sympathetic receptors
alpha & Beta
alpha1
G-protein class/Fx
q
increase vascular smooth mm contraction, increase pupillary dilator mm contraction (mydriasis), increased intestinal & bladder sphincter mm contraction
alpha2
G-protein class/Fx
i
decreased sympathetic outflow, decreased insulin release, decreased lipolysis, increased PLT aggregation
Beta1
G-protein class/Fx
s
increased heart rate, increased contractility, increased renin release, increased lipolysis
Beta2
G-protein class/Fx
Vasodilation, bronchodilation, increased HR, increased contractility, increased lipolysis, increased insulin release, decreased uterine tone (tocolysis), ciliary m relaxation, increased aqueous humor production
Parasympathetic receptors
M1, M2, M3
M1
G-protein class/Fx
q
CNS, enteric nervous system
M2
G-protein class/Fx
i
decreased HR & contractility of atria
Dopamine receptors
D1, D2
Dopamine receptors
D1, D2
alpha1
G-protein class/Fx
q
increase vascular smooth mm contraction, increase pupillary dilator mm contraction (mydriasis), increased intestinal & bladder sphincter mm contraction
alpha2
G-protein class/Fx
i
decreased sympathetic outflow, decreased insulin release, decreased lipolysis, increased PLT aggregation
Beta1
G-protein class/Fx
s
increased heart rate, increased contractility, increased renin release, increased lipolysis
Beta2
G-protein class/Fx
Vasodilation, bronchodilation, increased HR, increased contractility, increased lipolysis, increased insulin release, decreased uterine tone (tocolysis), ciliary m relaxation, increased aqueous humor production