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First Aid Pharm Chapter > Drug reactions > Flashcards

Drug reactions Flashcards

1
Q

coronary vasospasm

A

cocaine, sumatriptan, ergot alkaloids

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2
Q

cutaneous flushing

A

Vancomycin, Adenosine, Niacin, Calcium channel blockers (VANC)

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3
Q

dilated cardiomyopathy

A

anthracyclines (e.g., doxorubicin, daunorubicin); prevent with dexrazoxane

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4
Q

torsades de pointes

A

class III (e.g., sotalol) and class IA (e.g., quinidine) antiarrhythmics, macrolide antibiotics, antipsychotics, tricyclic antidepressants

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5
Q

hot flashes

A

tamoxifen, clomiphene

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6
Q

hyperglycemia

A

Tacrolimus, Protease inhibitors, Niacin, HCTZ, Corticosteroids (Taking Pills Necessitates Having Blood Checked)

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7
Q

hyperthyroidism

A

lithium, amiodarone, sulfonamides

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8
Q

acute cholestatic heptatitis, jaundice

A

erythromycin

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9
Q

diarrhea

A

Metformin, Erythromycin, Colchicine, Orlistate, Acarbose (Might Excite Colon On Accident)

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10
Q

focal to massive hepatic necrosis

A

Halothane, Amanita phalloides (death cap mushroom), Valproic acid, Acetaminophen (liver “HAVAc”)

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11
Q

hepatitis

A

rifampin, isoniazid, pyrazinamide, statins, fibrates

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12
Q

pancreatitis

A

Didanosine, Corticosteroids, Alcohol, Valproic acid, Azathioprine, Diuretics (furosemide, HCTZ) (Drugs Causing A Violent Abdominal Distress)

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13
Q

pseudomembranous colitis

A

clindamycin, ampicillin, cephalosporins

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14
Q

agranulocytosis

A

Ganciclovir, Clozapine, Carbamazepine, Colchicine, Methimazole, Propylthiouracil (Gangs CCCrush Myeloblasts and Promyelocytes)

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15
Q

aplastic anemia

A

Carbamazepine, Methimazole, NSAIDs, Benzene, Chloramphenicol, Prophylthiouracil (Can’t Make New Blood cells Properly)

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16
Q

direct coombs-positive hemolytic anemia

A

methydopa, penicillin

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17
Q

grey baby syndrome

A

chloramphenicol

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18
Q

hemolysis in G6PD deficiency

A

Isoniazid, Sulfonamides, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin (hemolysis IS D PAIN)

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19
Q

megaloblastic anemia

A

Phenytoin, Methotrexate, Sulfa drugs (having a BLAST with PMS)

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20
Q

thrombocytopenia

A

heparin

21
Q

thrombotic complications

A

OCPs, hormone replacement therapy

22
Q

fat redistribution

A

Protease Inhibitors, Glucocorticoids (fat PIG)

23
Q

gingival hyperplasia

A

phenytoin, calcium channel blockers, cyclosporine

24
Q

hyperuricemia/gout

A

Pyrazinamide, Thiazides, Furoseomide, Niacin, Cyclosporine (Painful Tophi and Feet Need Care)

25
Q

myopathy

A

fibrates, niacin, colchicine, hydroxychloroquine, interferon-alpha, penicillamine, statins, glucocorticoids

26
Q

osteoporosis

A

corticosteroids, heparin

27
Q

photosensitivity

A

Sulfonamides, Amiodarone, Tetracyclines, 5-FU (SAT For photo)

28
Q

rash (Stevens-Johnson syndrome)

A

anti-epileptic drugs (especially lamotrigine), allopurinol, sulfa drugs, penicillin (Steven Johnson has epileptic allergy to sulfa drugs and penicillin)

29
Q

SLE-like syndrome

A

Sulfa drugs, Hydralazine, Isoniazid, Procainamide, Phenytoin, Etanercept (having lupus is SHIPP-E)

30
Q

teeth discoloration

A

tetracyclines

31
Q

tendonitis, tendon rupture, and cartilage damage

A

fluoroquinolones (-oxacin)

32
Q

cinchoism (flushed and sweaty skin, tinnitus, blurred vision, impaired hearing, confusion, high-frequency hearing loss, headache, abdominal pain, rashes, vertigo, dizziness, dysphoria, nausea, vomiting and diarrhea)

A

quinidine, quinine

33
Q

Parkinson-like syndrome

A

Antipsychotics, Reserpine, Metoclopramide (coghweel rigidity of ARM)

34
Q

seizures

A

Isoniazid (vitamin B6 deficiency), Bupropion, Imipenem/cilastatin, Enflurane (with seizures, I BItE my tongue)

35
Q

tardive dyskinesia (involuntary facial/tongue movements)

A

antipsychotics, metoclopramide

36
Q

diabetes insipidus

A

lithium, demeclocycline

37
Q

Fanconi syndrome (disease of the proximal renal tubules in which glucose, amino acids, uric acid, phosphate and bicarbonate are passed into the urine, instead of being reabsorbed)

A

expired tetracycline

38
Q

hemorrhagic cystitis

A

cyclophosphamide, ifosfamide (chemotherapeutics); prevent by coadministering with mesna

39
Q

interstitial nephritis

A

methicillin, NSAIDs, furosemide

40
Q

SIADH

A

Carbamazepine, Cyclophosphamide, SSRIs (Can’t Concentrate Serum Sodium)

41
Q

dry cough

A

ACE inhibitors

42
Q

pulmonary fibrosis

A

Bleomycin, Amiodarone, Busulfan, Methotrexate (Breathing Air Badly from Medications)

43
Q

antimuscarinic

A

atropine, tricyclic antidepressants, H1-blockers, antipsychotics

44
Q

disulfiram-like reaction

A

metronidazole, certain cephalosporins, griseofulvin, procarbazine, 1st-generation sulfonylureas

45
Q

nephrotoxicity/ototoxicity

A

aminoglycosides, vancomycin, loop diuretics, cisplatin (cisplatin toxicity may respond to amifostine)

46
Q

cytochrome P450 inducers

A

Chronic alcohol use, St John’s wort, Phenytoin, Phenobarbital, Nevirapine, Rifampin, Griseofulvin, Carbamazapine (Chronic alcoholics Steal Phen-Phen and Never Refuse Greasy Carbs)

47
Q

cytochrome 450 substrates

A

Anti-epileptics, Theophylline, Warfarin, OCPs (Always Think When Outdoors)

48
Q

cytochrome P450 inhibitors

A

Acute alcohol abuse, Ritonavir, Amiodarone, Cimetidine, Ketoconazole, Sulfonamides, Isoniazid (INH), Grapefruit juice, Quinidine, Macrolides (except azithromycin) (AAA RACKS IN GQ Magazine)

First Aid Pharm Chapter (2 decks)

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