Antidotes Flashcards

1
Q

acetaminophen

A

N-acetylcysteine (acts as a reducing agent; provides sulfhydryl group to enhance non-toxic sulfation elimination)

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2
Q

AChE inhibitors (organophosphates = insecticides)

A

atropine > pralidoxime

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3
Q

amphetamines

A

ammonium chloride (acidify urine)

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4
Q

antimuscarinic, anticholinergic agents (i.e., atropine)

A

physostigmine, control hyperthermia

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5
Q

benzodiazepines

A

flumazenil

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6
Q

beta-blockers

A

glucagon

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7
Q

carbon monoxide

A

100% oxygen, hyperbaric oxygen

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8
Q

copper, arsenic, gold

A

penicillamine

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9
Q

cyanide

A

nitrite + thiosulfate, hydroxocobalamin (B12)

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10
Q

digitalis (digoxin)

A

anti-dig Fab fragments

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11
Q

heparin

A

protamine sulfate

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12
Q

iron

A

deFEroxamine, deFErasirox

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13
Q

lead

A

EDTA, dimercaprol, succimer, penicillamine

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14
Q

mercury, arsenic, gold

A

dimercaprol, succimer

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15
Q

methanol (wood alcohol), ethylene glycol (antifreeze)

A

fomepizole > ethanol, dialysis

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16
Q

methemoglobin

A

METHylene blue, vitamin C

17
Q

opioids

A

naloxone, naltrexone

18
Q

salicylates

A

sodium bicarbonate (alkalinize urine), dialysis

19
Q

tricyclic antidepressants

A

sodium bicarbonate (plasma alkalinization)

20
Q

tPA, streptokinase, urokinase

A

aminocaproic acid

21
Q

warfarin

A

vitamin K (delayed effect), fresh frozen plasma (immediate)

22
Q

rat poison

A

fresh frozen plasma, vitamin K