DRUG OF ABUSE Flashcards
1
Q
TLC
(Thin Layer Chromatography)
sensitivity
A
0.2-5
2
Q
- Uses enzyme-labeled drugs that compete with the drug in the sample
A
EMIT
2
Q
EIA sensitivity
A
0.025-5
2
Q
- Separates bound drugs from unbound drugs
A
ELISA
2
Q
GC sensitivity
A
0.01-10
2
Q
HPLC sensitivity
A
0.02-10
2
Q
GCMS sensitivity
A
0.001-5
3
Q
- More rapid than RIA
A
EMIT
3
Q
law for drig testing
A
- Comprehensive Dangerous Drugs Act of 2002 (R.A. 9165)
3
Q
- Fluorescent product
A
Umbelliferone
3
Q
- Drug binds to a fluorogenic substrate
A
Fluorescence Immunoassay
3
Q
- Serum is incubated with an antibody and a radiolabeled drug, competing for antibody binding sites.
A
RIA
3
Q
- Uses specific antibodies bound to a solid-state carrier
A
ELISA
3
Q
two fractions of RIA
A
1) Free fraction (unbound drug)
2) Antibody-bound drug
3
Q
- Adsorption of drug to a solid support and elution by means of a mobile and liquid phase
A
chromatography
3
Q
screening for drug identification
A
TLC
4
Q
for confirmatory drug ID
A
GCMS
4
Q
- Urine sample adjusted to ph 8.5
A
TLC
4
Q
ensure privacy protection, tamper prevention, and legal compliance
A
confidentiality
4
Q
- Have a high potential for abuse and addiction
A
1) Opiates and narcotic drugs
4
Q
- Drugs are separated on the basis of their ability to dissolve in the solvent system and its strength of interaction with the support phase
A
TLC
4
Q
- Most specific and sensitive, making it the gold standard
A
GCMS
4
Q
first stool produced by newborns
A
meconium
4
Q
- Color reactions are then used to locate and identify the specific substance
A
TLC
4
samples to detect chronic or long-term drug use
hair and nails
4
* Includes opioids
Opiates and narcotic drugs
4
Maintain specimen integrity, accountability, and detailed records of specimen handlers.
chain of custody
5
* Comprises drugs or medications primarily used for pain relief, including painkillers and analgesics
Opiates and narcotic drugs
5
tentative identification of drugs
Spectrophotometric
6
* Can significantly affect mental states
3) Hallucinogens
6
* Increase central nervous system (CNS) activity, enhancing mental and physical energy.
2) Stimulants
6
* Examples: cocaine, methamphetamine, prescription stimulants (e.g., fentanyl).
2) Stimulants
6
* Alter perceptions, thoughts, and feelings, often causing visual or auditory hallucinations
3) Hallucinogens
7
* Decrease CNS activity, leading to relaxation, drowsiness, and reduced inhibition.
4) Depressants, hypnotics and tranquilizers
7
* Often used to enhance social experiences
5) Club drugs
8
* Alter perceptions and increase energy, enhancing enjoyment of social activities
5) Club drugs
9
* Examples: Ecstasy, GHB (gamma-hydroxybutyrate).
5) Club drugs
10
* Enhance strength, endurance, and recovery
6) Athletic performance enhancers
11
primary active drug in opium
* Morphine
11
Can increase liver and pancreatic enzyme
* Morphine
11
2nd most abundant component; strong painkiller and cough suppressant
* Codeine
11
streetname of codeine
schoolboy
11
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