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Pharmacology I Exam #2 > Drug Names > Flashcards

Drug Names Flashcards

1
Q

What are the four classes of Beta-Lactam anitbiotics? What do these inhibit?

A

Inhibitors of Cell Wall Synthesis (ICWS)

  1. Penicillins
  2. Cephalosporins
  3. Monobactams
  4. Carbapenems
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2
Q

What are the other three classes of ICWS (NOT Beta-Lactam anitbiotics)? How is each administered?

A
  • Vancomycin (IM, oral)
  • Fosfomycin (oral)
  • Bacitracin (topical)
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3
Q

What are the two important Natural Penicillins?

A
  • Penicillin G

- Penicillin V

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4
Q

What are the three important Penicillinase-Resistant Penicillins?

A
  • Nafcillin
  • Dicloxacillin
  • Oxacillin
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5
Q

What are the two Extended Spectrum Penicillins?

A
  • Ampicillin

- Amoxicillin

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6
Q

What are the two Antipseudomonal Penicillins?

A
  • Piperacillin

- Ticarcillin

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7
Q

What is the primary toxicity concern with Pencillins?

A

Allergy

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8
Q

What are the two first generation Cephalosporins?

A
  • Cefazolin

- Cephalexin

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9
Q

What is the brand name for Cefazolin? How is it administered?

A

Cefazolin = Ancef
- IM, IV

First generation Cephalosporins

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10
Q

What is the brand name for Cephalexin? How is it administered?

A

Cephalexin = Keflex
- Oral

First generation Cephalosporins

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11
Q

What are the three second generation Cephalosporins?

A
  • Cefuroxime
  • Cefaclor
  • Cefprozil
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12
Q

What is the brand name for Cefuroxime? How is it administered?

A

Cefuroxime = Zinacef
- IM, IV

Second generation Cephalosporins

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13
Q

What is the brand name for Cefaclor? How is it administered?

A

Cefaclor = Ceclor
- Oral

Second generation Cephalosporins

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14
Q

What is the brand name for Cefprozil? How is it administered?

A

Cefprozil = Cefzil
- Oral

Second generation Cephalosporins

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15
Q

What are the four third generation Cephalosporins?

A
  • Ceftriaxone
  • Cefixime
  • Cefotaxime Sodium
  • Ceftazadime
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16
Q

What is the brand name for Ceftriaxone? How is it administered?

A

Ceftriaxone = Rocephin
- IM, IV

Third generation Cephalosporins

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17
Q

What is the brand name for Cefixime? How is it administered?

A

Cefixime = Suprax
- Oral

Third generation Cephalosporins

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18
Q

What is the brand name for Cefotaxime Sodium? How is it administered?

A

Cefotaxime Sodium = Claforan
- IM, IV

Third generation Cephalosporins

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19
Q

What is the brand name for Ceftazadime? How is it administered?

A

Ceftazadime = Fortaz
- IM, IV

Third generation Cephalosporins

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20
Q

What is the one fourth generation Cephalosporins?

A

Cefepime

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21
Q

What is the brand name for Cefepime? How is it administered?

A

Cefepime = Maxipime
- IV

Fourth generation Cephalosporins

22
Q

What is the one fifth generation Cephalosporins?

A

Ceftaroline

23
Q

What is the brand name for Ceftaroline? How is it administered?

A

Ceftaroline = Teflaro
- IV

Fifth generation Cephalosporins

24
Q

What is the one Monobactam antibiotic? What does this inhibit?

A

Aztreonam

ICWS

25
What is the brand name for Aztreonam? How is it administered?
Aztreonam = Azactam - IM, inhalation Monobactam antibiotic
26
What are the two important Carbapenem antibiotics? What do these inhibit?
- Imipinem; Cilastatin - Meropenem ICWS
27
What is the brand name for Imipinem; Cilastatin? How is it administered?
Imipinem; Cilastatin - IV Carbapenem antibiotic
28
What is the brand name for Meropenem? How is it administered?
Meropenem = Merrem - IV Carbapenem antibiotic
29
What do Cephalosporins inhibit?
ICWS
30
What are the three Macrolides? How is each administered? What do these inhibit?
- Erythromycin (oral, IV) - Azithromycin (oral, IV) - Clarithromycin (oral) IPS
31
What is the one important Ketolides? What does this inhibit?
Telithromycin (Ketek) IPS
32
What are the two Streptogramins? How should they be used? What do these inhibit?
- Dalfopristin - Quinupristin ALWAYS USE TOGETHER (Synercid) IPS
33
What is the one Oxazolidinones? What does this inhibit?
Linezolid IPS
34
Which two drug classes inhibit 30s ribosomal subunits? What type of functional inhibition is this?
IPS by inhibiting 30s ribosomal subunits - Aminoglycosides - Tetracyclines
35
What are the five Aminoglycosides? How is each administered?
- Streptomycin (IM, IV) - Gentamycin (IM, IV, topical) - Tobramycin (IM, IV, topical) - Amikacin (IM, IV) - Neomycin (oral, topical)
36
What are the three Broad Spectrum Antibiotics that IPS?
- Chloramphenicol - Tetracyclines - Glycylcyclines
37
What are the three Tetracyclines? How is each administered? What do they inhibit?
- Doxycycline (oral) - Tetracycline (oral, topical) - Minocycline (oral) IPS via inhibition of 30s ribosomal subunit
38
What is the one Glycylcyclines? How is it administered?
Tigecycline (IV)
39
What are the six Fluoroquinolones? What do they inhibit?
- Ciprofloxacin - Ofloxacin - Levofloxacin - Moxifloxacin - Gatifloxacin - Gemifloxacin Inhibit DNA gyrase (inhibit DNA replication)
40
What is the brand name for Ciprofloxacin?
Ciprofloxacin = Cipro Fluoroquinolones
41
What is the brand name for Ofloxacin?
Ofloxacin = Floxin Fluoroquinolones
42
What is the brand name for Levofloxacin?
Levofloxacin = Levaquin Fluoroquinolones
43
What are the two exclusive UTI antibiotics? How is each administered?
- Nitrofurantoin (oral) | - Methenamine (oral)
44
What is the brand name for Nitrofurantoin?
Nitrofurantoin = Furadantin Exclusive UTI antibiotic
45
What are the three Sulfonamides? What do these inhibit?
- Sulfamethoxazole + Trimethoprim - Sulfasalazine - Silver Sulfadiazine Inhibit PABA
46
What is the brand name for Sulfamethoxazole + Trimethoprim? What is another name for this drug?
Sulfamethoxazole + Trimethoprim = Bactrim = Co-trimoxazole Sulfonamides
47
What does Clindamycin inhibit? How is it administered?
IPS | - Oral, parenteral, topical
48
What is the MOA for Daptomycin?
Binds to cell membrane and causes a rapid depolarization of membrane potential - Loss of MP leads to inhibition of protein, DNA and RNA synthesis = cell death
49
What does Mupirocin inhibit?
Inhibits protein and RNA synthesis
50
What is the brand name for Mupirocin? How is it administered?
Mupirocin = Bactroban | - IV
51
What are the two Polypeptide antibiotics?
- Polymyxin B | - Colistin
52
What is the MOA for Polypeptide antibiotics?
Binds to cell membrane phospholipids (lipid A of endotoxin) | - Polypeptide antibiotics are Polymyxin B and Colistin

Pharmacology I Exam #2 (5 decks)

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