Drug Mechanism Of Action

Question 1

Acyclovir

Valacyclovir

Answer 1

Metabolized to acyclovir triphosphate,

which inhibits viral DNA Polymerase

Question 2

Amantadine

Answer 2

Blockage of the M2 protein ion channel and it’s ability to modulate intracellular pH

Question 3

Cidofovir

Answer 3

Inhibition of viral DNA polymerase

Question 4

Famciclovir

Penciclovir

Answer 4

Metabolized to penciclovir triphosphate, which Inhibits viral DNA polymerase

Question 5

Foscarnet

Answer 5

Inhibition of viral DNA polymerase and Reverse Transcriptase at pyrophosphate- binding site

Question 6

Ganciclovir

Answer 6

Inhibits viral DNA polymerase

Question 7

Interferon-a

Answer 7

Induction of cellular enzymes that interfere with viral protein synthesis.

Question 8

Lamivudin

Answer 8

Inhibition of viral DNA polymerase and Reverse Transcriptase

Question 9

Oseltamivir

Answer 9

Inhibition of viral neuramidase

Question 10

Ribavirin

Answer 10

Interference with viral messenger RNA

Question 11

Rimantadine

Answer 11

Blockage of the M2 protein ion channel and it’s ability to modulate intracellular pH

Question 12

Vidarabine

Answer 12

Inhibits viral DNA synthesis

Question 13

Zanamivir

Answer 13

Inhibition of viral neuramidase