Drug List 5 Flashcards
Aminosteril® 5%
Amino acid
Parenteral nutrition
Solution (Infusion)
MOA: provide nutrition into the body by supplying needed amino acid
CI: amino acid metabolism problems
PC: Sulfite allergy
ADR: unexplained weight gain
Amphotret®
Amphotericin B
Invasive fungal infection (Candidiasis)
lyophilized powder (Intravenous)
MOA: Binds to ergosterol causing intracellular leakage
CI: Hypersensitivity
PC: not be used to treat noninvasive forms of fungal disease
ADR: multiple organ failure
Marcaine®
Bupivacaine
Labor pain
Solution, Liposomal suspension (Intraspinal)
MOA: Binds to Sodium channels to block sodium influx to nerve cells, blocking nerve impulse
CI: —
PC: convulsions due to systemic toxicity
ADR: convulsions
Sandimmune®
Cyclosporine
Immunosuppression in organ transplant
Capsule, Solution (Oral)
Emulsion (Ophthalmic)
MOA: Inhibits the production and release of interleukin II
CI: Rheumatoid arthritis
PC: Renal impairment
ADR: hepatitis
Dextran 70
RescueFlow®
hypovolemic shock
Solution (infusion)
MOA: nonprotein colloid and plasma volume expander, It reduces blood viscosity and has antiplatelet effect
CI: bleeding disorders
PC: hemorrhage
ADR: Severe anaphylactic reactions
Epogen®
Epoetin α
chronic kidney disease
Solution (IV, SC)
MOA: same actions as endogenous erythropoietin which maintain a healthy amount of red blood cells
CI: hypertension
PC: increase the risk of Cardiovascular events
ADR: transient ischemic attack,
Lanexat®
Flumazenil
Benzodiazepine poisoning
Solution (Intravenous)
MOA: Competitive inhibitor of GABA
CI: —
PC: Benzodiazepine reversal may result in seizures.
ADR: Abnormal hearing
Pedia-lax®
Chewable tab: Magnesium Hydroxide
Supp: Liquid Glycerin
Oral Soln: docusate Na
Enema: Saline
Constipation (OTC)
Hepabig®
Hepatitis B Immunoglobulin
prophylaxis to hepatitis B
Solution (Intramuscular)
MOA: passive immunization for individuals exposed to the hepatitis B virus by binding to the surface antigen
CI: Allergy
PC: coagulation disorders
ADR: Tremor and hypotension
Heparin
Hepastar 5000®
thromboembolic disorders
Solution (IV, SC)
MOA: enhancing the inhibition rate of clotting proteases, antithrombin III
CI: —
PC: Hemorrhage may occur
ADR: —
Venofer®
Iron sucrose
iron-deficiency anemia
Solution (Intravenous)
MOA: iron is incorporated into hemoglobin to mature into red blood
CI: Iron overload
PC: only be administered
when personnel immediately available
ADR: severe hypotension.
Forane®
Isoflurane
Induction of general anesthesia
Solution (Inhalation)
MOA: halogenated methyl ester that
produces profound respiratory depression and alter activity of neuronal ion channels
CI: history of hepatitis
PC: Increased intracranial pressure
ADR: —
Keppra®
Levetiracetam
Epilepsy
Tablet, Solution (Oral)
Solution (IV)
MOA: facilitation of GABA-ergic inhibitory transmission by displacing negative modulators
CI: Hypersensitivity
PC: pre-existing cardiac disease
ADR: Suicidal ideation
Lipidem®
Atorvastatin
Hyperlipidemia
Tablet (Oral)
MOA: selective, competitive inhibitor of HMG-CoA reductase preventing convertion to mevalonate, limiting cholesterol biosynthesis.
CI: Active liver disease,
PC: Liver dysfunction
ADR: pancreatitis
Gelofusine®
Succinylated gelatin
hypovolemia
Solution (Intravenous)
MOA: colloidal plasma substitutes that exert osmotic pressure to
maintain circulatory volume.
CI: Hypervolemia;
PC: Renal insufficiency
ADR: hypertension,
Nubain®
Nalbuphine
Severe pain (DD - Sched 4)
Solution (IV, IM, SC)
MOA: Binds to opiate receptors to produce analgesic effects
CI: bronchial asthma
PC: respiratory depression
ADR: bradycardia
Zofran®
Ondansetron
nausea and vomiting in chemotherapy
Solution (IV, IM)
MOA: selective 5-HT3 receptor inhibitor blocking its effect on vagal afferent nerves
CI: use of apomorphine
PC: gastric distention.
ADR: Abdominal pain
Diprivan®
Propofol
Induction of general anesthesia;
Emulsion (Intravenous)
MOA: GABA inhibitorand associated with minimal respiratory depression
CI: Hypersensitivity to eggs
PC: Lipid disorders
ADR: Myoclonus
Herceptin®
Trastuzumab
breast cancer
lyophilized powder, Solution (IV, SC)
MOA: monoclonal antibody that binds with HER-2 protein and inhibiting proliferation of cells
CI: Hypersensitivity to Chinese
hamster ovary (CHO) cell proteins
PC: Hazardous agent
ADR: blood coagulation disorder
Vastarel® MR
Trimetazidine
Stable angina
Tablet (Oral)
MOA: A fatty acid oxidation (pFOX) inhibitor that alters metabolism to
maintain intracellular ATP levels in ischemic regions
CI: Parkinson disease;
PC: Renal impairment
ADR: Parkinsonian symptoms
