Drug Interactions with Receptors and Ion Channels Flashcards

1
Q

Adenosine

A

Adenosine R agonist

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2
Q

Atropine

A

Non-selective muscarinic cholinergic R antagonist

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3
Q

Bay K 8644

A

Calcium agonist

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4
Q

Benzilylcholine mustard

A

Non-selective irreversible muscarinic cholinergic R antagonist

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5
Q

Benzocaine

A

Voltage-gated Na+ channel blocker

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6
Q

α-bungarotoxin

A

Irreversible, selective for NMJ, competitive nicotinic acetylcholine R antagonist

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7
Q

Cholera toxin

A

αs subunit GTPase activity inhibitor

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8
Q

Diltiazem

A

Myocyte voltage-gated calcium channel blocker

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9
Q

D-tubocurarine

A

Non-selective nicotinic cholinergic R antagonist

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10
Q

Ethinylestradiol

A

Oestrogen R agonist

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11
Q

Glibenclamide

A

Sulphonylurea R agonist

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12
Q

Isoprenaline

A

Non-selective β-adrenoceptor agonist

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13
Q

Lidocaine/lignocaine

A

Na+ channel block

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14
Q

Minoxidil

A

K+ (ATP) channel opener

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15
Q

Nicorandil

A

K+ (ATP) channel opener

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16
Q

Nifedipine

A

L-type Ca2+ channel blocker

17
Q

Norethisterone

A

Progesterone R agonist

18
Q

Pertussis toxin

A

αi subunit inhibitor

19
Q

Prednisolone

A

Short acting lucocorticoid R agonist

20
Q

Quinidine

A

Na+, Ca2+, K+ channels blocker

21
Q

Spironolactone

A

Competitive • aldosterone/mineralocorticoid R antagonist

22
Q

Tamoxifen

A

Oestrogen R antagonist

23
Q

Tetrodotoxin

A

Na+ channel blocker

24
Q

Tyrphostins

A

Tyrosine kinase inhibitor

25
Q

Verapamil

A

Myocyte Ca2+ channel blocker